Gene Information

Name : nadE (MGAS10750_Spy1466)
Accession : YP_602960.1
Strain : Streptococcus pyogenes MGAS10750
Genome accession: NC_008024
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : -
Position : 1403413 - 1404279 bp
Length : 867 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
TTGATAACATTCGTAAAGATACTCATGGAAAGAGTGAATGACATGACATTACAAGAAGAGATAATTCGACAATTAGGCGT
CAAGGCTAGCATTGATCCACAAGAAGAAATTCGAAAAACCGTTGATTTTTTAAAAGCTTATTTGCGTAAGCACTCATTTT
TAAAAACTTATGTCTTAGGCATTTCGGGAGGTCAGGATTCTACCCTCGCAGGAAAGCTAGCCCAGATGGCCATTGCAGAG
TTACGGGAGGAAGCAAGTGATCAAGCTTACCAATTTATAGCTGTTCGCTTGCCTTATGGGGTTCAGGCTGATGAAGCAGA
TGCGCAAAAAGCCTTGGCTTTTATTGCACCAGATCAGACCCTTACCATTAATATCAAGGCAGCTGTGGACGGTCAAGTAG
AGGCTCTACAAGCAGCAGGCGTTGAGATTTCTGATTTCAATAAAGGTAATATTAAAGCACGTCAGCGAATGATCAGTCAA
TATGCCATTGCTGGCCAAATGGCCGGTGCTGTTATTGGAACGGATCATGCGGCAGAAAACATCACTGGTTTCTTTACTAA
ATTTGGTGATGGTGGAGCAGATATTCTTCCCCTCTTTAGGCTTAACAAACGTCAAGGAAAGGCTCTTTTGAAAGTTTTAG
GAGCAGATGCTGCTTTGTATGAAAAAGTTCCAACTGCTGATTTAGAAGATCAAAAACCAGGCTTGGCTGATGAGGTTGCC
CTAGGGGTGACCTATCAAGACATCGACGACTATTTGGAAGGGAAGCTGATTTCCAAAGTAGCTCAAGCAACTATTGAAAA
ATGGTGGCATAAAGGACAACACAAGCGTCACCTGCCAATCACCATTTTTGATGATTTTTGGAAATAA

Protein sequence :
MITFVKILMERVNDMTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAE
LREEASDQAYQFIAVRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQ
YAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVA
LGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 2e-62 54