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Name : nrdE2 (MGAS10750_Spy1226) Accession : YP_602720.1 Strain : Streptococcus pyogenes MGAS10750 Genome accession: NC_008024 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit alpha Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0209 EC number : - Position : 1171802 - 1173961 bp Length : 2160 bp Strand : + Note : Catalyzes the rate-limiting step in dNTP synthesis DNA sequence : ATGAGTCTCAAAGATCTTGGCGATATTTCATATTTTCGCCTAAATAATGAAATTAACCGTCCTGTTAATGGTAAAATTCC ACTTCATAAAGACAAAGAAGCTTTAAAAGCTTTTTTCGCTGAAAATGTGCTGCCAAACACCATGTCTTTTACTTCCATTA CGGAAAAAATTGAGTATTTAATCTCAAATGATTACATTGAATCAGCTTTTATTCAGAAATACCACCCTGAATTTATTACT GAATTAGCTAGCATAATCAAATCAGAAAATTTTCGCTTTAAATCATTTATGGCAGCCTACAAGTTCTACCAGCAATACGC CTTAAAAACAAATGATGGAGAGCATTATTTAGAAAACCTTGAAGACCGTGTCTTGTTTAATGCTTTGTATTTTGCAGATG GTCAAGAAGACTTAGCAAAAGATTTAGCCGTTGAAATGATTAACCAACGTTACCAACCGGCTACTCCTTCCTTTTTAAAT GCTGGTCGAAGCCGTCGTGGTGAATTGGTCTCTTGTTTCTTGATTCAAGTAACTGATGACATGAATTCTATCGGACGTTC CATTAACTCTGCCTTGCAATTATCCCGTATTGGTGGAGGTGTTGGGATTACCTTGTCTAACCTCCGTGAAGCTGGCGCAC CAATCAAAGGCTATGCTGGTGCAGCCTCAGGAGTTGTTCCTGTTATGAAATTATTTGAAGATAGTTTTTCTTATTCAAAT CAACTTGGGCAACGTCAAGGAGCTGGTGTTGTTTACCTAAATGTTTTTCATCCTGATATCATTGCTTTCTTATCTACTAA AAAAGAAAATGCCGATGAAAAGGTGCGTGTTAAAACCTTGTCACTAGGGATTACCGTTCCTGATAAATTCTACGAATTAG CTCGTAAAAACGAGGACATGTATCTCTTTAGTCCTTACAATGTTGAAAAAGAATATGGCATTCCCTTTAACTATCTCGAC ATTACCAATATGTACGATGAGTTAGTGGCGAACCCTAAAATTACTAAGACTAAAATTAAAGCTCGTGATCTTGAAACAGA GATTTCAAAATTACAACAAGAATCTGGTTACCCTTATATCATCAATATTGATACAGCTAATAAAACTAATCCTATCGATG GAAAAATCATCATGAGCAACTTGTGTTCTGAAATTTTACAAGTTCAAACACCTAGCCTTATCAATGATGCGCAAGAGTTT GTAGAAATGGGAACTGATATTTCATGTAACTTAGGTTCCACTAATATCCTGAACATGATGACCTCACCAGACTTTGGCCG TTCTATTAAGACCATGACACGTGCCCTAACTTTTGTTACTGATTCATCAAGCATTGAAGCTGTTCCAACCATTAAACATG GCAATAGCCAAGCTCATACTTTTGGCCTTGGAGCTATGGGACTACATTCTTACCTTGCTCAACATCATATTGAATATGGC AGTCCAGAATCCATCGAGTTTACTGATATTTACTTTATGCTCCTGAATTATTGGACCTTGGTCGAATCCAATAACATCGC TCGTGAGCGCCAAACTACCTTTGTTGGCTTTGAGAACTCTAAGTACGCTGATGGTAGTTACTTTGATAAATACGTTACAG GACACTTTGTTCCAAAATCTGATTTGGTCAAAAGTCTCTTTAAAGACCATTTTATTCCGCAAGCTTCAGATTGGGAGGCT CTTCGCGACGCCGTTCAAAAAGATGGTCTTTATCATCAAAACCGACTAGCAGTTGCTCCAAATGGCTCTATTTCTTATAT CAATGACTGCTCTGCTTCTATTCACCCAATCACACAACGCATCGAAGAGCGTCAAGAAAAGAAAATTGGTAAAATCTACT ATCCTGCAAATGGTTTGTCTACGGATACCATTCCTTACTATACATCTGCTTACGATATGGACATGCGCAAAGTTATTGAT GTCTATGCCGCTGCGACCGAACATGTGGACCAAGGCTTGTCATTAACTCTATTCCTTCGTAGTGAGTTGCCTATGGAGCT TTATGAGTGGAAAACACAAAGCAAACAAACCACTCGTGATTTATCCATCTTACGAAACTACGCTTTCAATAAAGGCATTA AATCTATCTACTATATCCGTACCTTTACGGATGATGGGGAAGAAGTGGGCGCAAACCAATGTGAATCTTGTGTCATTTAA Protein sequence : MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVLPNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFIT ELASIIKSENFRFKSFMAAYKFYQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYAGAASGVVPVMKLFEDSFSYSN QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLD ITNMYDELVANPKITKTKIKARDLETEISKLQQESGYPYIINIDTANKTNPIDGKIIMSNLCSEILQVQTPSLINDAQEF VEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPTIKHGNSQAHTFGLGAMGLHSYLAQHHIEYG SPESIEFTDIYFMLLNYWTLVESNNIARERQTTFVGFENSKYADGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQASDWEA LRDAVQKDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTIPYYTSAYDMDMRKVID VYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLSILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1481 | YP_001800875.1 | ribonucleotide-diphosphate reductase subunit alpha | Not tested | Not named | Protein | 3e-178 | 51 |
