Gene Information

Name : hasB (MGAS2096_Spy1883)
Accession : YP_601479.1
Strain : Streptococcus pyogenes MGAS2096
Genome accession: NC_008023
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 1841789 - 1842997 bp
Length : 1209 bp
Strand : +
Note : -

DNA sequence :
ATGAAAATAGCAGTTGCTGGATCAGGATATGTTGGATTATCACTAGGAGTTCTTTTATCACTTCAAAACGAAGTCACTAT
TGTTGATATTCTTCCCTCTAAAGTTGATAAGATTAATAATGGCTTATCACCAATTCAAGATGAATATATTGAATATTACT
TAAAAAGTAAGCAATTATCTATTAAAGCAACTTTAGATAGCAAAGCAGCTTATAAAGAAGCGGAACTGGTCATTATTGCC
ACACCTACAAATTACAACAGTAGAATTAATTATTTTGATACACAGCATGTTGAAACAGTTATCAAAGAGGTACTAAGCGT
TAATAGCCATGCAACTCTTATCATCAAATCAACAATTCCAATAGGTTTCATTACTGAAATGAGACAGAAATTCCAAACTG
ATCGTATTATCTTCAGCCCTGAATTTTTAAGAGAGTCTAAAGCTTTATATGACAACTTATATCCAAGCCGAATTATTGTT
TCTTGTGAAGAAAACGATTCTCCAAAAGTAAAGGCAGACGCAGAAAAATTTGCACTTTTATTAAAGTCTGCAGCTAAAAA
AAATAATGTACCAGTACTTATTATGGGAGCTTCAGAAGCTGAAGCAGTAAAACTATTTGCCAATACTTATTTAGCGTTAA
GGGTAGCTTATTTTAATGAGTTAGACACTTACGCAGAATCGAGAAAATTAAATAGTCACATGATTATTCAAGGAATTTCT
CATGATGATCGAATAGGAATGCATTATAATAACCCATCATTTGGTTATGGAGGTTATTGTCTACCTAAAGATACGAAGCA
ATTATTGGCAAATTACAATAATATTCCCCAAACGCTAATTGAAGCTATCGTTTCATCAAATAATGTGCGCAAGTCCTATA
TTGCTAAGCAAATTATCAACGTCTTAGAAGAGCGGGAGTCCCCAGTAAAAGTAGTTGGGGTTTACCGTTTAATTATGAAA
AGTAACTCAGATAATTTTAGAGAAAGTGCTATCAAAGATGTTATTGACATTCTTAAAAGTAAAGACATTAAGATAATTAT
TTATGAGCCAATGTTAAACAAACTTGAATCTGAAGATCAATCTGTACTTGTAAATGATTTAGAGAATTTCAAGAAACAAG
CAAATATTATCGTAACTAATCGCTATGATAATGAATTACAAGATGTTAAAAATAAAGTTTACAGTAGAGATATTTTTAAT
AGAGACTAG

Protein sequence :
MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSIKATLDSKAAYKEAELVIIA
TPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIV
SCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMIIQGIS
HDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLEERESPVKVVGVYRLIMK
SNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFN
RD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 8e-71 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasB YP_601479.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 3e-158 99