Gene Information

Name : MGAS2096_Spy1540 (MGAS2096_Spy1540)
Accession : YP_601136.2
Strain : Streptococcus pyogenes MGAS2096
Genome accession: NC_008023
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 1484167 - 1485381 bp
Length : 1215 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGAAAATTATTGAAAAATCATCAAAATTAGAACATGTTGCCTATGATATTCGAGGGCCTGTTTTGGATGAAGCTAATCG
CATGATTGCGAGTGGTGAAAAAATTCTGCGTTTAAATACTGGCAATCCTGCTGCCTTTGGTTTTGAAGCACCAGATGAAG
TGATTCGTGATTTAATTGTCAACGCGAGGCTAAGTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCGCGTAAGGCT
ATCATGCAATATTGTCAACTCAAGGGCTTCCCAGATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTT
GATATCCATGTCCCTTCAAGCTTTGCTAGATAATGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGG
CTTGTGTGAGTCTTGGTGGAGGAAAAGCGGTCCATTATCTTTGTGATGAAGAAGCTGGTTGGTATCCTGATATTGCTGAT
ATCAAATCAAAAATCACGAGTCGCACCAAAGCTATTGTGGTCATCAATCCTAATAACCCAACAGGAGCTCTTTATCCTAA
GGAGATTTTAGAAGACATCGTTGCTTTGGCAAGAGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGG
TGATGGATAGTAAAGAGCATATTGCTATTGCAAGTTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGCCTTTCCAAA
TCTCATCGTATTGCTGGTTTTCGTGTTGGATGGATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGG
GTTAAACATGCTTGCCAATATGCGGTTATGCTCCAATGTTTTAGCCCAACAAGTTGTTCAAACTTCCTTAGGAGGTCATC
AATCAGTTGATGCACTGTTACTGCCAGGAGGGCGTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATC
CCTGGCTTATCGGCAGTTAAACCTGAGGCAGGTCTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGA
TGATGAAGAATTTGTCTTACAGTTATTAAAGCAAGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATC
CAGATCACTTCCGTATTGTTTACCTACCAAGTGTAGAAGAATTAGAAGATGTCCAAGAAAAGATTACACGTGTCTTATAC
CAGTATAGACGTTAA

Protein sequence :
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDSKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 4e-117 57
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 4e-117 57
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 4e-117 57
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 4e-117 57