Gene Information

Name : serS (MGAS2096_Spy1510)
Accession : YP_601106.1
Strain : Streptococcus pyogenes MGAS2096
Genome accession: NC_008023
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1457683 - 1458960 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATCTTAAACGTATCCGTACTGATTTTGACACTGTCGCTGCCAAATTAAAAAACCGTGGTGTTTCTGAAGACAC
CCTGACCCATCTTAAAGAACTTGATGAAAAACGTCGTACTCTATTAGTGCAATCAGAAGAATTAAAAGCAGAGCGTAATA
TTGCTTCTGCTGCCATCGCTCAAGCCAAACGTCAAAAAGAAGATGCCACTCAACAAATTGCTGATATGCAAAAAGTCTCT
GCAGATATCAAAACTATTGACAATCAACTAGTAGCTATCGACCAGCAAGTTACTGACATCATCACTGTTTTACCTAATAC
TCCTCACGATTCTGTCCCTGTTGGAGCTGACGAAGAAGACAATGTCGAAATTCGCCGTTGGGGAACGCCTCGTGACTTTA
ACTTCGAAGTTAAGGCTCATTGGGATCTAGGCGAAGATCTTGATATTTTAGACTGGGAACGTGGGGCAAAGGTAACTGGT
GCTCGTTTCTTATTCTATAAAAATCTTGGTGCTCGTTTGGAGCGTGCTCTTTATAACTTCATGCTGGATGAACATATCAA
AGAAGGTTATCAAGAAATCATCACACCTTACATGGTTAACCACGATTCCATGTTTGGTACAGGACAATATCCAAAGTTCA
AAGAGGACACCTTTGAATTAGCAGATACCAACTTTGTCCTGATTCCAACTGCTGAAGTGCCTTTGACCAATTATTACCGT
GGGGAAATCCTAGACGGCAAAGAATTGCCAATTTACTTTACTGCAATGAGCCCATCTTTTCGTTCTGAAGCGGGTTCTGC
GGGTCGTGACACACGTGGCCTTATCCGCCTACACCAATTCCACAAAGTTGAAATGGTTAAATTTGCTAAACCAGAAGAAT
CTTACCAAGAACTAGAAAAAATGACTGCTAATGCTGAAAATATTCTTCAAAAACTTGGTTTGCCATATCGCGTCATTTCC
CTTTGTACTGGCGACATGGGCTTCTCAGCTGCTAAAACCTATGACCTTGAAGTCTGGATTCCTGCACAAAACACCTACCG
TGAAATTTCATCATGTTCAAATACTGAAGATTTCCAAGCACGACGTGCTCAAATCCGTTACCGTGATGAGGCTGACGGTA
AGGTCAAACTTCTCCACACCCTTAATGGGTCAGGACTTGCTGTCGGTCGTACCGTAGCAGCCATTTTAGAAAACTACCAA
AATGAAGATGGTTCTGTTACCATCCCTGAAGTACTCCGCCCTTACATGGGTGGCGAAACCGTCATTTCACCTAAATAA

Protein sequence :
MLDLKRIRTDFDTVAAKLKNRGVSEDTLTHLKELDEKRRTLLVQSEELKAERNIASAAIAQAKRQKEDATQQIADMQKVS
ADIKTIDNQLVAIDQQVTDIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFNFEVKAHWDLGEDLDILDWERGAKVTG
ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELADTNFVLIPTAEVPLTNYYR
GEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVIS
LCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQ
NEDGSVTIPEVLRPYMGGETVISPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-176 83