Gene Information

Name : lysS (MGAS10270_Spy0488)
Accession : YP_598097.1
Strain : Streptococcus pyogenes MGAS10270
Genome accession: NC_008022
Putative virulence/resistance : Virulence
Product : Lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 476935 - 478440 bp
Length : 1506 bp
Strand : -
Note : -

DNA sequence :
TTGGAGGAAAATATGTCTAATCAACACATCGAAGAATTAAATGACCAACAGATTGTCCGTCGTGAAAAGATGATGGCTCT
GGCTGAACAAGGAATTGATCCTTTCGGTAAACGCTTTGACCGCACAGCCAATTCTGCTGAATTAAAAGAAAAGTATGCTG
ATAAAACAAAAGAAGAATTACATGAGTTAAACGAAACAGCTATTGTTGCTGGCCGCTTGATGACAAAACGTGGCAAAGGT
AAGGTTGGTTTTGCTCATCTTCAAGACCGGGAAGGCCAAATCCAACTTTATGTTCGCAAGGACTCTGTTGGCGAAGACAA
CTATGAAATCTTCAAAAAAGCCGATTTAGGCGACTTTATCGGCGTTGAAGGCGAAGTCATGCGTACAGACATGGGCGAGT
TGTCAATCAAGGCAACCAAGTTGACTCACCTTTCTAAATCACTTCGTCCTCTTCCTGAAAAATTCCACGGATTAACTGAT
ATTGAAACCATTTACCGTAAGCGTCACCTTGATTTAATTTCAAATCGTGAAAGCTTTGACCGCTTCGTGACCCGTTCCAA
AATGATTTCAGAAATCCGTCGTTATTTAGACGGTCTTGATTTCCTAGAAGTAGAAACGCCTGTGCTTCATAACGAAGCTG
GTGGTGCTGCTGCTCGTCCTTTCGTTACTCACCATAATGCTCAAAACATTGACATGGTACTTCGTATCGCAACAGAACTT
CATTTGAAACGTTTGATTGTTGGTGGTATGGAACGTGTCTATGAAATTGGTCGTATCTTCCGTAACGAGGGAATGGATGC
TACTCATAATCCTGAGTTCACTTCTATTGAGGTTTACCAAGCCTATGCAGACTATCTTGATATCATGAACCTGACAGAAG
GCATTATCCAACATGCTGCTAAAGCTGTTAAAGGTGATGGCCCTATTGATTATCAAGGAACCGAAATCCGTATCAATGAA
CCTTTCAAACGTGTTCACATGGTAGATGCTATCAAGGAAGTGACAGGTGTTGATTTCTGGCCTGAAATGACTGTCGAAGA
AGCTATTGCACTTGCCAAAGAAAAACAGGTCCCACTCGAAAAACACTTCACAAGTGTCGGACATATCATCAATGCTTTCT
TCGAGGAATTTGTTGAAGAAACCTTGGTCCAACCAACCTTTGTGTTTGGTCATCCTGTTGAAGTATCGCCTTTGGCTAAG
AAGAATCCAGAAGATACCCGCTTCACCGACCGCTTCGAACTTTTCATCATGACCAAAGAATACGCCAATGCTTTCACAGA
GTTAAATGATCCCATTGACCAATTATCTCGTTTTGAAGCACAAGCACAAGCCAAAGAACTTGGTGATGACGAAGCAACTG
GCATTGACTACGACTTCGTTGAAGCTCTTGAATATGGTATGCCGCCAACCGGTGGACTCGGAATTGGTATTGACCGTCTT
TGCATGTTATTAACAAACACAACAACTATCAGAGATGTGCTTTTATTCCCAACGATGAAACCTTAA

Protein sequence :
MEENMSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAELKEKYADKTKEELHELNETAIVAGRLMTKRGKG
KVGFAHLQDREGQIQLYVRKDSVGEDNYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTD
IETIYRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFVTHHNAQNIDMVLRIATEL
HLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEIRINE
PFKRVHMVDAIKEVTGVDFWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVSPLAK
KNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRL
CMLLTNTTTIRDVLLFPTMKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 9e-106 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_598097.1 Lysyl-tRNA synthetase VFG1668 Protein 5e-106 47