Gene Information

Name : MGAS10270_Spy0450 (MGAS10270_Spy0450)
Accession : YP_598059.1
Strain : Streptococcus pyogenes MGAS10270
Genome accession: NC_008022
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 446624 - 447781 bp
Length : 1158 bp
Strand : +
Note : -

DNA sequence : 
ATGAAAATTACAGTTGTAGGCATTGGATACGTTGGATTATCGATAGGGCTCCTACTTGCAAAGGAACACGACGTTACCTT
TTTTGATATTGATAATAAAAAAATTGATTTAATAAATAAAAGGCAATCCTCTCTTAAAGAAGCAGCTATAAACAAACTTT
TATGTAAGGCAAAAAATATTAATGCAACTTCTTCTGAAGAATTAGCATATAAGGATGCGACTTTCATAATCTTGTCTTTG
CCAACCAACCTAAAAGTTAATAAGCTTGATACTTCCATTATCGAAATTTCTGTAAGTAATATTTTAAAGATAAACAAAAA
GGCTACAATTGTAATAAAGTCGACAGTTCCAATTGGTTTTACAGAATATTTAAGGAATCGATTTCACTACAACGATATCA
TTTTTTCACCTGAGTTCCTTAGGGAAGGATCAACTATTCATGATCAATTGTATCCTTCGAGAACTATAGTTGGAAATGAA
TCTAGAAATTCTCAATTATTCTTAGACATACTAACAGATATATCGGTTGAAAAAGACTCGCCATCTTTATTAGTTGGCTC
TTCTGAAGCAGAAGCGATAAAGTTATTTTCGAATGCATACTTGGCACAAAAAATTGCTTTTTTTAATGAGTTGGATACGT
TTGCTGAAATGCAAAATTTGGACTCAAAAAAAATTATTGAGGCTATGGGATATGACCAGAGAATAGGAAATTCGCACAAT
AATCCTTCTTTCGGTTTTGGTGGGTACTGTCTTCCTAAGGATATTAAGCAATTAGAGTATCATTTTAAAGAAATTCCAGC
ACCAATTATTACCAGTATAAGTGAGTCTAATTTATTAAGAAAAATTCATATAGCAAAAATGATTTTGAACAGCTCAGCTA
AAACAATAGGAATTTATAGAATTAATTCCAAAAAAGATTCGGATAATTGTAGGGAATCTTCTACAATTGATGTTGCTAAA
CTTCTAAAAAGCAGTGGTAAGGATGTTATCATCTTTGAGCCCTTAATTAACCAAAAAAAGTTTTTGGGGTGCCCTTTAAT
TAATGATTTTAATGAATTTATTAAATATTCGGATATTATAGTTGCCAATAGAATAGATGATGCTCTGAGAAAATGTAATT
CAAAAGTTTTTACACGTGATATTTTTCAGTATGATTAA

Protein sequence : 
MKITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSSLKEAAINKLLCKAKNINATSSEELAYKDATFIILSL
PTNLKVNKLDTSIIEISVSNILKINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNE
SRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNELDTFAEMQNLDSKKIIEAMGYDQRIGNSHN
NPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKMILNSSAKTIGIYRINSKKDSDNCRESSTIDVAK
LLKSSGKDVIIFEPLINQKKFLGCPLINDFNEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 2e-60 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MGAS10270_Spy0450 YP_598059.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 4e-70 45