Gene Information

Name : tkt (MGAS10270_Spy1493)
Accession : YP_599102.3
Strain : Streptococcus pyogenes MGAS10270
Genome accession: NC_008022
Putative virulence/resistance : Unknown
Product : Transketolase
Function : -
COG functional category : -
COG ID : -
EC number : 2.2.1.1
Position : 1438504 - 1440693 bp
Length : 2190 bp
Strand : -
Note : -

DNA sequence :
GTGGCCACTGTGTCAACAGGCTCTCTTATATTCATCGTCAAAAAGAATTCACCAATGATGTCCAAACTAGTTTTTTTCTG
GCAAAATAGAGAAAAAGAATTTAGGGACTTTGGAGGATTTTCTGAAAAAAGCGTCTATTTTTGTGATACAATAGACAATA
GAAAACGTTTAATTTTAGTTGTAATAAACAGAGAGGTTTTACTTATGACATTTGATGCAATTGACCAGTTGGCAGTAAAC
ACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTCTGGACACCCAGGACTTCCAATGGGGGCAGCACCTAT
GGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAACAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCC
TATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACACTTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAG
AACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGTGAACCACACAGACGGTGTCGAAGCAACCACAGGACC
TCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAGAAGCTCATCTAGCAGCTAAATTTAACAAACCAGGCT
TTGACATCGTTGATCACTACACCTTTGCTTTGAATGGTGACGGTGACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGT
ATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGATTCAAACGACATCTCTCTTGATGGTCCAACCTCTAT
GGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTTGGCAACATATCCTTGTGAAAGATGGAAATGATTTAG
AAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAGAAACCAACCATCATCGAAGTCAAAACCATTATTGGT
TTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCCTCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGC
TTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAACAGAGCGCTTTGCTCAAGGTCTTCAAGCGCGTGGTG
AAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATGAAGCAGAATATCCAGAATTAGCAGCAGAATACCAAAAA
GCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGAACTTGGTAGTTCAATGGCGAGTCGTGTATCCAGTCA
ACAAGCCATCCAACAAATTTCAGAACAAGTAGCCTCTTTCTGGGGTGGGTCAGCAGACCTTTCAGCTTCAAACAATACTA
TGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGCCGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATG
GCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGTTTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCT
TCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAGTTTATGTCATGACACATGATTCTATCGCTGTCGGTG
AAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTTCGCTCAATGCCTAACTTGAACGTTATTCGTCCAGCA
GACGGTAACGAAATAAATGCTGCTTGGAAACGTGCCATTGCTGAAACAGATCGCCCAACCATGCTTGTATTGACGCGTCA
AAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATGGTCTTAACAAAGGAGCTTATATCTTGTCAGAAGCCA
AAGGCGACCTTGATGGTATCTTGATTGCAACAGGTTCAGAAGTGAAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCA
GAAGGCATTCATGTGCGTGTCGTATCTATGCCATCACAAAATATCTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCAT
CCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTTCAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAG
GAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGAAATCGTATCTTCGAAGAATATGGTTTCACTGTGGCA
AATGCAACTGAGTTATACAAATCACTCTAA

Protein sequence :
MATVSTGSLIFIVKKNSPMMSKLVFFWQNREKEFRDFGGFSEKSVYFCDTIDNRKRLILVVINREVLLMTFDAIDQLAVN
TVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLK
NFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDGDLMEGVSQEAAS
MAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIG
FGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTERFAQGLQARGEKAEQAWNDLFAAYEAEYPELAAEYQK
AFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEGRNIWFGVREFAM
AAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPA
DGNEINAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGILIATGSEVKLAMDTQEALEA
EGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPGNRIFEEYGFTVA
NATELYKSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-126 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-125 49