Gene Information

Name : MGAS10270_Spy1238 (MGAS10270_Spy1238)
Accession : YP_598847.1
Strain : Streptococcus pyogenes MGAS10270
Genome accession: NC_008022
Putative virulence/resistance : Unknown
Product : Lead, cadmium, zinc and mercury transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.-
Position : 1194129 - 1195991 bp
Length : 1863 bp
Strand : -
Note : -

DNA sequence :
ATGACAATCAGACAATGGATGGCAGACCATCTTCATTTAATGGAGACTTTAGCGTGTTTGGTATTAATAATAATTGGCCT
AGCCTTTTTACACTCATTTCCACAAGTGGCTTCCGCTATTTTCATTACAGCCTTCTTGATTGGAGGATATGCGTCTGCAA
AAACGGGTATATTGGATTTGGTGAAGAACAAACACTTGTCAGTGGATATTTTGATGATTTTGGCAGCTATCGGTGCTGGA
ATTATCGGCTATTGGCTGGAGGGTGCTCTGCTTATTTTTATCTTTTCGTTGTCCAATACGCTTGAAGAAATGGCCATGGA
AAAAAGTAAGGATGCTATTTCAGCCTTGATGTCCTTGACGCCAGATACAGCTCGTCAATACCAAGAAGATGGCCATATTT
TAGAAGTTGAGACCAGATCCTTGAGTGTTGGTGACCGTTTACAAGTTCGTAAAGGCGAAGCTGTTCCAATTGACGGGCAG
TTGCTTAGTCCTTTTGGTCAATTTGATGAATCTATGGTCACTGGTGAGCCTATCACTGTTGATAAGGCAGAAGGCCAGGA
TCTGATTGGGGGAACCATTAACCAAGGACAAACCATAGATATGTTGGTTACTATTGAAAATGACGATACTCTCTTTGCCA
AGATTATTAATCTGGTGGAATCTGCCCAAGAAAAGAAAAGCAAAACCGCCACCTTTATCGAAAGCTTAGAAGATGGTTAT
GTCAAATTTGTGCTCGTCCTTATTCCTGCCTTTATCCTCTTTAGCCACTTTGTGTTTTCTTGGACTTGGTTGGCTGCTTT
TTACCGAGGGATGATTCTCTTAACAGTAGCTTCACCATGTGCCCTAATTGCCAGTTCCACACCTGCTAGCTTGGCTGCTA
TTTCTCGTGCAGCCAGAAAGGGATTGATTATCAAAGGAGGGGATATTGTCAATAACATGGGAGATATTAAGGCTGTTGTC
ATGGATAAAACGGGAACGCTCACCCAAGGAAAACCTTCTGTTGTGAATGCTCATTATTTGAAAGATGAGTTGCTCGTGAA
TAGACTGGTAAAAGGAGCAGAGGCTGCTAGTACCCATCCTATTTCTAAAGCCCTTCTTGAATACACTGAAAAATTGGAGC
CACTGACCTTTGACCACTTAGAAGAAATTTCTGGGAAAGGTTTTCAGGGCTTCTATCAAGGGCAAGAATGGCGAATTGGC
AAGAAAACCTTCATTTTGGAAAAGGTTCAAGACCTATCAGCTTTTGAAGAAACTATTCAAGTGGAAGAAAATCAAGGGAA
AACCCTAATCTTTGTTTCACGTGACCATCAATTGATAGCTTACTATGCCCTCTTGGATGATATCAAAATAGAATCAAAAC
GTGCTATTGAGTCTCTTCATGCCATGGGAATCAAGACAGTCATGTTAACAGGTGACCAAGAACGAACCGCCAATTATGTG
GCACAAAAACTTGGTATTGATGAAGTGGTAGCCAACTGTATGCCTCAAGATAAGGTGGCTAAGTTAGCAGAATTAAAGAC
CAAATATGGTTTTGTGGCCATGGTAGGAGATGGTATTAATGATGCTCCTGCCCTTGCTCAAGCAGATGTTTCTTATGCTA
TTGGATCAGGAACAGATATTGCAATGGAAAGTGCAGACAGTGTGATTATGGATGACTTGACTCGTATTCCATTTTCGATT
CAACTTTCCCGCAAAATGAAGACCATTATCAAACAAAATATTGTTTTTGCCTTATCTGTGATTACCTTATTGATTTTAGC
CAATGTTTTTCAGGTAGTTAACTTGCCGCTTGGTGTTGTTGGACACGAAGGCTCAACGATTTTAGTGATTTTAAATGGCT
TGCGTTTACTTTCTTTTAAATAA

Protein sequence :
MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAFLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAG
IIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGY
VKFVLVLIPAFILFSHFVFSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARKGLIIKGGDIVNNMGDIKAVV
MDKTGTLTQGKPSVVNAHYLKDELLVNRLVKGAEAASTHPISKALLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIG
KKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYALLDDIKIESKRAIESLHAMGIKTVMLTGDQERTANYV
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSI
QLSRKMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 2e-93 41
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 2e-93 41