Gene Information

Name : nadC (MGAS9429_Spy0172)
Accession : YP_595904.1
Strain : Streptococcus pyogenes MGAS9429
Genome accession: NC_008021
Putative virulence/resistance : Unknown
Product : nicotinate-nucleotide pyrophosphorylase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0157
EC number : 2.4.2.19
Position : 186805 - 187704 bp
Length : 900 bp
Strand : +
Note : catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide

DNA sequence :
GTGATATTAAAAATAGAGGACTTAGTGATGTCAATCATTTCAACTGATTTAACCCCTTTTCAAATAGATGATACATTGAA
AGCAGCCTTGCGAGAAGATGTTCATTCCGAAGATTACAGTACCAATGCCATTTTTGATCATCATGGCCAAGCCAAGGTGT
CGCTTTTTGCCAAGGAAGCTGGTGTTTTAGCGGGGCTAACCGTTTTTCAAAGGGTTTTTACCCTATTTGATGCCGAGGTG
ACCTTCCAGAATCCTCATCAATTTAAGGATGGGGATCGTTTGACTAGTGGCGATTTGGTTTTAGAAATCATAGGCTCGGT
GAGAAGCCTCTTAACATGTGAACGCGTTGCCTTGAATTTTTTACAACATTTATCAGGGATTGCTTCGATGACAGCTGCTT
ATGTAGAAGCCTTAGGCGATGATCGCATTAAGGTATTTGATACTCGAAAAACCACTCCTAATTTACGTCTTTTTGAGAAA
TATGCCGTGAGAGTTGGCGGTGGCTATAATCATCGCTTTAATTTATCAGATGCTATCATGCTAAAAGACAATCACATTGC
GGCAGTAGGTAGTGTTCAAAAGGCGATTGCTCAAGCGCGTGCCTATGCCCCTTTTGTGAAAATGGTCGAGGTGGAAGTGG
AAAGCCTTGCTGCTGCCGAAGAAGCTGCGGCGGCGGGTGTTGATATTATCATGTTGGATAATATGTCATTGGAACAGATT
GAACAGGCCATTACTCTAATTGCAGGACGTTCTCGGATTGAATGTTCTGGAAATATTGATATGACCACTATTAGCCGTTT
TCGTGGTTTAGCGATTGATTACATCTCCAGTGGTAGTTTAACCCATAGTGCTAAGAGTCTCGATTTTTCCATGAAGGGTT
TAACCTACCTTGATGTCTAA

Protein sequence :
MILKIEDLVMSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKVSLFAKEAGVLAGLTVFQRVFTLFDAEV
TFQNPHQFKDGDRLTSGDLVLEIIGSVRSLLTCERVALNFLQHLSGIASMTAAYVEALGDDRIKVFDTRKTTPNLRLFEK
YAVRVGGGYNHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGVDIIMLDNMSLEQI
EQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYISSGSLTHSAKSLDFSMKGLTYLDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadC YP_281534.1 nicotinate-nucleotide pyrophosphorylase Not tested Not named Protein 8e-124 99