Gene Information

Name : purA (MGAS9429_Spy0138)
Accession : YP_595870.1
Strain : Streptococcus pyogenes MGAS9429
Genome accession: NC_008021
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 151700 - 152992 bp
Length : 1293 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGACATCTGTAGTTGTTGTTGGTACCCAGTGGGGTGACGAAGGTAAAGGTAAAATCACTGATTTCTTGTCAGCGGATGC
AGAAGTAATTGCTCGCTATCAAGGTGGTGATAATGCTGGTCATACGATCGTGATTGATGGTAAGAAGTTTAAACTTCACT
TGATCCCATCAGGAATTTTCTTCCCGCAAAAAATTTCCGTTATTGGTAATGGCGTTGTGGTCAACCCCAAATCTTTGGTC
AAAGAGTTGGCGTACCTGCATGATGAAGGAGTGACGACAGATAACCTTCGCATTTCAGACCGAGCTCATGTTATTTTACC
TTATCATATCCAGCTGGATCAACTGCAAGAAGATGCAAAAGGTGACAATAAAATCGGAACAACTATTAAAGGGATTGGTC
CAGCTTATATGGATAAAGCTGCTCGAGTTGGTATCCGTATCGCAGATTTACTGGATAAGGATATCTTTGCAGAGCGCCTA
CGCATTAATTTAGCTGAGAAAAACCGTTTATTTGAAAAAATGTATGACAGTACACCTCTTGGTTTTGATGCTATCTTTGA
GGAGTACTATGCTTACGGTCAAGAAATCAAGCAATATGTGACAGATACTTCTGTGATTTTAAATGATGCACTTGATGCTG
GTAAACGTGTTCTTTTTGAAGGTGCTCAAGGGGTTATGCTTGATATTGACCAAGGAACTTACCCATTTGTAACGTCTTCA
AACCCAGTTGCTGGTGGTGTAACCATTGGTTCTGGTGTTGGCCCAAGTAAAATCAACAAAGTAGTTGGTGTCTGTAAAGC
CTACACAAGCCGTGTCGGTGATGGGCCATTCCCTACAGAACTCTTTGATGAAGTGGGTGAGCGCATTCGTGAAGTGGGTC
ATGAGTACGGGACAACGACCGGCCGTCCACGTCGTGTCGGTTGGTTTGACTCAGTTGTTATGCGCCATAGTCGTCGTGTG
TCAGGGATTACTAACCTCTCTCTGAATTCAATTGATGTTCTTTCAGGGCTTGATACGGTTAAGATTTGTGTGGCTTATGA
CCTTGATGGGAAACGTATTGACTATTACCCAGCAAGCCTTGAACAACTCAAACGTTGCAAACCAATCTATGAAGAATTAC
CAGGCTGGCAAGAGGACATCACAGGTGTTCGTAGCCTTGATGAGCTTCCTGAAAATGCCCGCAACTACGTTCGTCGTGTT
GGAGAATTGGTTGGCGTTCGCATTTCAACCTTCTCAGTTGGTCCAGGGCGTGAACAGACCAATATTCTTGAGTCAGTCTG
GGCATCTATCTAA

Protein sequence :
MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLV
KELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
RINLAEKNRLFEKMYDSTPLGFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSS
NPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRV
SGITNLSLNSIDVLSGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRV
GELVGVRISTFSVGPGREQTNILESVWASI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 0.0 100