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Name : nrdE2 (MGAS9429_Spy1170) Accession : YP_596901.1 Strain : Streptococcus pyogenes MGAS9429 Genome accession: NC_008021 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit alpha Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0209 EC number : 1.17.4.1 Position : 1126334 - 1128493 bp Length : 2160 bp Strand : + Note : Catalyzes the rate-limiting step in dNTP synthesis DNA sequence : ATGAGTCTCAAAGATCTTGGCGATATTTCATATTTTCGCCTAAATAATGAAATTAACCGTCCTGTTAATGGTAAAATTCC ACTTCATAAAGACAAAGAAGCTTTAAAAGCTTTTTTCGCTGAAAATGTGCTGCCAAACACCATGTCTTTTACTTCCATTA CGGAAAAAATTGAGTATTTAATCTCAAATGATTACATTGAATCAGCTTTTATTCAGAAATACCACCCTGAATTTATTACT GAATTAGCTGGCATAATCAAATCAGAAAATTTTCGCTTTAAATCATTTATGGCAGCCTACAAGTTCTACCAGCAATACGC CTTAAAAACAAATGATGGAGAGCATTATTTAGAAAACCTTGAAGACCGCGTCTTGTTTAATGCTTTGTATTTTGCAGATG GTCAAGAAGACTTAGCAAAAGATTTAGCCGTTGAAATGATTAACCAACGTTACCAACCGGCTACTCCTTCCTTTTTAAAT GCTGGTCGAAGCCGTCGTGGTGAATTGGTCTCTTGTTTCTTGATTCAAGTAACTGATGACATGAACTCTATCGGACGTTC TATCAACTCTGCTTTGCAATTATCCCGTATTGGTGGAGGTGTTGGGATTACCTTGTCTAACCTCCGTGAAGCTGGCGCAC CAATCAAAGGCTATGCTGGTGCAGCCTCAGGAGTTGTTCCTGTTATGAAATTATTTGAAGATAGTTTTTCTTATTCAAAT CAACTTGGGCAACGTCAAGGAGCTGGTGTTGTTTACCTAAATGTTTTTCATCCTGATATCATTGCTTTCTTATCTACTAA AAAAGAAAATGCCGATGAAAAGGTACGTGTTAAAACCTTGTCACTAGGGATTACCGTTCCTGATAAATTCTACGAATTAG CTCGTAAAAACGAGGACATGTATCTCTTTAGTCCTTACAATGTTGAAAAAGAATATGGCATTCCCTTTAACTATCTCGAC ATTACCAATATGTACGATGAGTTAGTGGCAAACCCTAAAATTACTAAGACTAAAATTAAAGCTCGTGATCTTGAAACAGA GATTTCAAAATTACAACAAGAATCTGGTTACCCTTATATCATCAATATTGATACAGCTAATAAAGCTAATCCTATCAATG GAAAAATCATCATGAGCAACTTGTGTTCTGAAATTTTACAAGTTCAAACACCTAGCCTTATCAATGATGCGCAAGAGTTT GTAGAAATGGGAACTGATATTTCATGTAACTTAGGTTCCACTAATATCCTGAACATGATGACCTCACCAGACTTTGGCCG TTCTATTAAGACCATGACACGTGCCCTAACTTTTGTTACTGATTCATCAAGCATTGAAGCTGTTCCAACCATTAAACATG GCAATAGCCAAGCTCATACTTTTGGCCTTGGAGCTATGGGACTACATTCTTACCTTGCTCAACATCATATTGAATATGGC AGTCCAGAATCCATCGAGTTTACTGATATTTACTTTATGCTCCTGAATTATTGGACCTTGGTCGAATCCAATAACATCGC TCGTGAGCGCCAAACTACCTTTGTTGGCTTTGAGAACTCTAAGTACGCTAATGGTAGTTACTTTGATAAATACGTTACAG GACACTTTGTTCCAAAATCTGATTTGGTCAAAAGTCTCTTTAAAGATCACTTTATTCCTCAAGCAGAGGATTGGAAAGCT CTTCGCGACGCCGTTCAAAAAGATGGTCTTTATCATCAAAACCGTCTAGCAGTTGCTCCAAATGGCTCTATTTCTTATAT CAATGACTGCTCTGCTTCTATTCACCCAATCACACAACGCATCGAAGAGCGTCAAGAAAAGAAAATTGGTAAAATCTACT ATCCTGCAAATGGTTTGTCTACGGATACCATTCCTTACTATACATCTGCTTACGATATGGACATGCGCAAAGTTATTGAT GTCTATGCCGCTGCGACCGAACATGTGGACCAAGGCTTGTCATTAACTCTATTCCTTCGTAGTGAGTTGCCTATGGAGCT TTATGAGTGGAAAACACAAAGCAAACAAACCACTCGTGATTTATCCATCTTACGAAACTACGCTTTCAATAAAGGCATTA AATCTATCTACTATATCCGTACCTTTACGGATGATGGGGAAGAAGTGGGCGCAAACCAATGTGAATCTTGTGTCATTTAA Protein sequence : MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVLPNTMSFTSITEKIEYLISNDYIESAFIQKYHPEFIT ELAGIIKSENFRFKSFMAAYKFYQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYAGAASGVVPVMKLFEDSFSYSN QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLD ITNMYDELVANPKITKTKIKARDLETEISKLQQESGYPYIINIDTANKANPINGKIIMSNLCSEILQVQTPSLINDAQEF VEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPTIKHGNSQAHTFGLGAMGLHSYLAQHHIEYG SPESIEFTDIYFMLLNYWTLVESNNIARERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKSLFKDHFIPQAEDWKA LRDAVQKDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTIPYYTSAYDMDMRKVID VYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLSILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1481 | YP_001800875.1 | ribonucleotide-diphosphate reductase subunit alpha | Not tested | Not named | Protein | 2e-178 | 51 |
