Gene Information

Name : yscV (LI0548)
Accession : YP_594923.1
Strain : Lawsonia intracellularis PHE/MN1-00
Genome accession: NC_008011
Putative virulence/resistance : Virulence
Product : type III secretion pore protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 666726 - 668828 bp
Length : 2103 bp
Strand : +
Note : -

DNA sequence :
ATGAGCTTATTCGCTAAAGCTCAATCGACTGTAGGTGTTATTACACGAAATAATGACATCACTATGGTCCTTTTATTAGT
GACTGTCATAGCATTAATGATTATCCCATTACCTACTCCTTTAGTGGATACACTGATTGGTATTAACATGGGACTTTCAT
TTCTTATTGTAATGATGTGTATGTATGTTAAGACAGTTTTAGATTTTTCTGTTTTTCCCACTATGCTCCTTTTTACAACC
CTGTTCAGAGTTGGTTTAAATATCACAACGACAAGACTTATTTTACTCCAAGCAGATGCTGGAGAAATCATTTTTATTTT
TGGTGAATTTGCCTTAGGTGGAAACTTTGTTGTTGGAGCAGTTGTCTTTGTCATTCTAACAATTGTTCAGTTCCTTGTTA
TTGCAAAAGGAGCTGAACGTGTTGCCGAAGTTGGTGCACGCTTTACCCTTGATGCTATGCCAGGAAAACAGATGTCTATT
GATGCCGACATGCGCGCAGGCGTTATTGACATGGAAGAAGCCCAAAAACGTCGTGCACGAATAAATCAAGAAAGCCAAAT
GTATGGAGCTATGGACGGTGCTATGAAATTTGTTAAAGGTGATAGCATCGCAGGAATGATAATTGCTGTTGTTAATATTG
TTGGAGGTACCATTATTGGGGTCACACAACATGGAATGGCTGCCTCTGATGCCTTACATGTTTATGGTATTCTGACCATT
GGTGATGGTTTAGTCTCACAAATTCCATCTCTGTTAATCTCCATTGCAGCAGGGATTCTGATTACTCGTACTGGTGACTC
AGCTGAAAATGTTGGTTCTCAAATTGGTGAACAAATATTTAATCAGCCTAAAGCTCTTTTAATGGCAGGTGGAGTTGTAT
TTCTTATTGCACTAGTTCCAGGTTTTCCAAAAATTCAACTTTTTGCCATTTCAGCTACTCTTGCAGGTATTGGGTATACA
CTAAAACTTATTATGACTAACCCTGCACCTAAAAATGCAAAACAAAGTATAGCAAAAACATTAGAACCTACAACATCACC
TTCAAAAAAATCTTCTACTGAACAGAAGGAATCAAAAGAAGAGTTTTCACCAACTGTACCTATTATATTAGATATATCTC
AACAAATGAGTGAAGAGTTAGATTATGATTCACTCAATGATGAACTTATAACATTACGTCGTGTTCTATACTTTGATCTT
GGTGTACCATTCCCTGGCATTAATCTTCGCATCTCATCAAAGCTACATGACCTTACTTATTCCTTAATGATTAATGAGAT
TCCTATAACCAAAGGAACACTTGAAAAAGGTATGGTCTTAGCAAGGGATACAAAAGAAAATTTGGCAATGCTTGGAGTGG
AACCTGAAGAAAAAGAAAAATTTCTTCCAGATGTTGAGTCTCTTTGGGTTCCAGACTCTAAAAAAGCATTGCTTGAACGG
GCAGGAATAACATGTATGACACATAGTCGCATTCTTGCTTACCACTTATCCCTTGTCCTTTCACGCCATGCTTCAAACTT
TCTGGGCATGCAAGAAACAAAATATCTCTTGGATAAAATGGAAGAACGTGCTCCTGATTTGGTTAGAGAAACAACTCGAT
TATTACCTGTACAAAGAATTGCTGAAATTTTCCAACGTCTTGTACAAGAACAAATTTCTATACGTGACTTAAGAAGTATC
CTTGAGGCTCTTATTGAGTGGAGCCCTAAAGAAAAAGATACTGTTATGCTCACAGAATATGTCCGAAGTGCGTTAAAACG
TCAAATAAGTTACATGTACTCTAAAGGTCAAAACATGCTACCTGCTGTTCTTCTTGATCCAAACGTAGAAGAAACTATTA
GAAAATCTGTAAGACAAACTTCTGCTGGGGCCTTCCTTGCATTAGATCCAGAAACAACACAAATATTTATGGCATCCCTT
AAAGAGTTTGCATCAGAGACCAATCTAACCTATACCCAAAAACCTGTTTTAATCACTTCAATGGATATTCGTCGGTATGT
ACGTAGACTCATAGAGGGAGATTATTACAACCTTCCTGTAGTGTCATACCAAGAACTTACACCAGAAATTTCTGTACAAC
CTGTTGGAAGAATACGTTTCTAA

Protein sequence :
MSLFAKAQSTVGVITRNNDITMVLLLVTVIALMIIPLPTPLVDTLIGINMGLSFLIVMMCMYVKTVLDFSVFPTMLLFTT
LFRVGLNITTTRLILLQADAGEIIFIFGEFALGGNFVVGAVVFVILTIVQFLVIAKGAERVAEVGARFTLDAMPGKQMSI
DADMRAGVIDMEEAQKRRARINQESQMYGAMDGAMKFVKGDSIAGMIIAVVNIVGGTIIGVTQHGMAASDALHVYGILTI
GDGLVSQIPSLLISIAAGILITRTGDSAENVGSQIGEQIFNQPKALLMAGGVVFLIALVPGFPKIQLFAISATLAGIGYT
LKLIMTNPAPKNAKQSIAKTLEPTTSPSKKSSTEQKESKEEFSPTVPIILDISQQMSEELDYDSLNDELITLRRVLYFDL
GVPFPGINLRISSKLHDLTYSLMINEIPITKGTLEKGMVLARDTKENLAMLGVEPEEKEKFLPDVESLWVPDSKKALLER
AGITCMTHSRILAYHLSLVLSRHASNFLGMQETKYLLDKMEERAPDLVRETTRLLPVQRIAEIFQRLVQEQISIRDLRSI
LEALIEWSPKEKDTVMLTEYVRSALKRQISYMYSKGQNMLPAVLLDPNVEETIRKSVRQTSAGAFLALDPETTQIFMASL
KEFASETNLTYTQKPVLITSMDIRRYVRRLIEGDYYNLPVVSYQELTPEISVQPVGRIRF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lssD AAO18050.1 LssD Virulence TTSS locus Protein 7e-154 51
hrcV AAP34346.1 HrcV Virulence Hrp PAI Protein 3e-92 43
hrcV YP_362156.1 HrcV protein Virulence Hrp PAI Protein 5e-92 43
hrcV NP_640760.1 HrcV protein Virulence Hrp PAI Protein 3e-92 43
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 2e-107 43
XC_3013 YP_244081.1 HrcV protein Virulence Hrp PAI Protein 1e-86 42
hrcV NP_636603.1 protein HrcV Virulence Hrp PAI Protein 1e-86 42
hrcV YP_198723.1 protein HrcV Virulence Hrp PAI Protein 6e-90 42
hrcV BAB07859.1 HrcV Virulence Hrp PAI Protein 5e-90 42
ECs3731 NP_311758.1 EivA Not tested LIM Protein 1e-100 42
invA AAS66860.1 InvA Not tested SSR-2 Protein 4e-91 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yscV YP_594923.1 type III secretion pore protein VFG0064 Protein 2e-166 54
yscV YP_594923.1 type III secretion pore protein VFG0198 Protein 2e-146 52
yscV YP_594923.1 type III secretion pore protein VFG0384 Protein 7e-152 50
yscV YP_594923.1 type III secretion pore protein VFG2126 Protein 4e-121 45
yscV YP_594923.1 type III secretion pore protein VFG1006 Protein 3e-97 41
yscV YP_594923.1 type III secretion pore protein VFG2461 Protein 6e-100 41