Gene Information

Name : tetW (LI0179)
Accession : YP_594556.1
Strain : Lawsonia intracellularis PHE/MN1-00
Genome accession: NC_008011
Putative virulence/resistance : Resistance
Product : ribosomal protection tetracycline resistance protein
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0480
EC number : -
Position : 225939 - 227858 bp
Length : 1920 bp
Strand : -
Note : -

DNA sequence :
ATGAACATTATCAATATCGGGATTCTTGCCCATGTAGATGCGGGCAAGACGACACTGACAGAAAGCCTGCTGTATGCCAG
CGGAACCATTTCAGAGCCGGGGAGCGTCGAAAAAGGGACAACGAGAACGGACACTATGTTTTTGGAGCGGCAGCGTGGAA
TTACCATTCAAACGGCAGTCACTTCTTTCCAGTGGCACAGTTGTAAAGTCAATATTGTGGATACTCCCGGCCACATGGAT
TTCTTGGCAGAGGTATACCGCTCTCTGGCTGTTTTGGACGGGGCCATCTTGGTGCTCTCCGCTAAAGATGGCGTGCAGGC
CCAGACCCGTGTTCTGTTCCATGCCCTACGGAAATTGAACATCCCCACCATTATCTTTATCAACAAGATCGACCAGGTTG
GCATTGATTTGGAGAGCGTATATCAGTCTGTTCGGGATAAGCTCTCCGCTGATATTATCATCAAGCAGACAGTGTCGCTG
TCCTCGAAAATAACTCTGACAGAAAACACTAGTGCAGAGGTTTGGGATTCGGTCATCGAAAATAACGATGAGTTATTGGC
AAAGTATATCGCAGGAGAATCAATCAGTCAGAAAGAACTTGCGCAAGAAGAACAGCGGCGAGTTCAAGACGCCTCCCTGC
TCCCGGTCTATCATGGTAGCGCCAAAAACGGCCTTGGCATTCAACAGTTGATGGATGCGGTGATAGGGCTGTTCCAATCG
ACCAAGGAACAGGGGAGCGCCGCCCTGTGCGGTAGAGTTTTTAAGGTGGAGTATACAGATTGCGGCCAGAGGCTTGTCTA
TCTGCGGCTATACAGCGGAACGCTGCGTCTGCGGGATACGGTGGCCCTAGCCGGGAGAGAAAAGCTGAAAATCACAGAGA
TGCGTATTCCATCCAAAGGGGAGATTGTTCGGACAGATACCGCCCATAAGGGCGAAATTGTCATCCTTCCCAGCGACAGC
TTGAGATTAAACGATATATTGGGGGACAAAACCCAACTTCCTCGTGAAATGTGGAGTGATGTTCCCTTCCCTATGCTGCG
GACGACGATTACGCCAAAAACGGCAGAGCAAAGAGACCGGTTGCTGGACGCTCTTACGCAAATTGCGGATACTGACCCGC
TTTTGCACTACGAGGTGGATTCCACCACCCATGAGATCATTCTTTCTTTTTTGGGTCGGATGCAGTTGGAGGTTGTTTCC
GCTTTGCTGACGGAAAAATACAAGATTGAAACAGCAGTGAAGGAACCCACCGTCATTTATTTAGAGCGGCCGCTCAAAGT
GGCCAGTCACACCATCCATATCGAGGTGCCGCCTAACCCGTTTTGGGCATCTATCGGACTGTCTGTTACACCGCTCCCGC
TTGGCTCCGGTGTAAAATACGAGAGCCGGGTTTCCCTGGGATACCTGAACCAGAGTTTTCAAAACGCTGTCATGGATGGT
ATCCGTTACGGTTTGGGGCAAGGCTTGTGTGGCTGGAACGTAACGGACTGTAAGATTTGCTTTGAATACGGACTTTACTA
TAGCCCGGTCAGTACGCCGGCGGACTTCCGCTCATTGGCCCCGATTGTATTGGAACAGGCATTGAAGAAATCTGGGACGC
AGTTGCTGGAACCTTATCTCTCCTTCACCCTCTATGCGCCCCAGGAATACCTTTCCAGGGCTTATCATGATGCGCCGAAA
TACTGTGCCACCATCGAAACGGCCCAGATAAAAAAGGATGAAGTTGTCTTTACTGGCGAGATTCCCGCCCGTTGCATACA
GGCATACCGTACTGATTTGGCCTTTTACACCAACGGGCGGAGTGTGTGCCTGACGGAACTGAAAGGGTATCAGGCCACTG
TCGGCGAGCCAATCATCCAGCCCCGTCGTCCAAACAGCCGTTTGGATAAGGTGCGCCATATGTTCAGTAAGATTCCTTGA

Protein sequence :
MNIINIGILAHVDAGKTTLTESLLYASGTISEPGSVEKGTTRTDTMFLERQRGITIQTAVTSFQWHSCKVNIVDTPGHMD
FLAEVYRSLAVLDGAILVLSAKDGVQAQTRVLFHALRKLNIPTIIFINKIDQVGIDLESVYQSVRDKLSADIIIKQTVSL
SSKITLTENTSAEVWDSVIENNDELLAKYIAGESISQKELAQEEQRRVQDASLLPVYHGSAKNGLGIQQLMDAVIGLFQS
TKEQGSAALCGRVFKVEYTDCGQRLVYLRLYSGTLRLRDTVALAGREKLKITEMRIPSKGEIVRTDTAHKGEIVILPSDS
LRLNDILGDKTQLPREMWSDVPFPMLRTTITPKTAEQRDRLLDALTQIADTDPLLHYEVDSTTHEIILSFLGRMQLEVVS
ALLTEKYKIETAVKEPTVIYLERPLKVASHTIHIEVPPNPFWASIGLSVTPLPLGSGVKYESRVSLGYLNQSFQNAVMDG
IRYGLGQGLCGWNVTDCKICFEYGLYYSPVSTPADFRSLAPIVLEQALKKSGTQLLEPYLSFTLYAPQEYLSRAYHDAPK
YCATIETAQIKKDEVVFTGEIPARCIQAYRTDLAFYTNGRSVCLTELKGYQATVGEPIIQPRRPNSRLDKVRHMFSKIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tet(W) YP_005160006.1 tetracycline resistance protein Not tested Not named Protein 0.0 88
SSU05_0922 YP_001198287.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 69
SSU98_0928 YP_001200485.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 69
tetO AFJ97266.1 truncated tetracycline resistant protein Not tested Not named Protein 3e-142 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetW YP_594556.1 ribosomal protection tetracycline resistance protein AJ222769.gene.p01 Protein 0.0 89
tetW YP_594556.1 ribosomal protection tetracycline resistance protein DQ294299.gene.p01 Protein 0.0 88
tetW YP_594556.1 ribosomal protection tetracycline resistance protein AY485126.gene.p01 Protein 0.0 87
tetW YP_594556.1 ribosomal protection tetracycline resistance protein AJ295238.gene.p01 Protein 0.0 70
tetW YP_594556.1 ribosomal protection tetracycline resistance protein NC_009782.5559075.p0 Protein 0.0 69
tetW YP_594556.1 ribosomal protection tetracycline resistance protein AM180355.1.gene636.p Protein 0.0 69
tetW YP_594556.1 ribosomal protection tetracycline resistance protein NC_002758.1120355.p0 Protein 0.0 69
tetW YP_594556.1 ribosomal protection tetracycline resistance protein X04388.gene.p01 Protein 0.0 69
tetW YP_594556.1 ribosomal protection tetracycline resistance protein M85225.gene.p01 Protein 0.0 69
tetW YP_594556.1 ribosomal protection tetracycline resistance protein L09756.gene.p01 Protein 0.0 68
tetW YP_594556.1 ribosomal protection tetracycline resistance protein FN594949.1.gene24.p0 Protein 0.0 68
tetW YP_594556.1 ribosomal protection tetracycline resistance protein L42544.gene.p01 Protein 1e-129 44
tetW YP_594556.1 ribosomal protection tetracycline resistance protein AJ514254.gene.p01 Protein 8e-117 43
tetW YP_594556.1 ribosomal protection tetracycline resistance protein Z21523.gene.p01 Protein 3e-107 42