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Name : leuS (LI0152) Accession : YP_594530.1 Strain : Lawsonia intracellularis PHE/MN1-00 Genome accession: NC_008011 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 190747 - 193254 bp Length : 2508 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGATAATGCATTCTAATTATGATCCTAACATTATTGAAAAGAAATGGCAGCGTTACTGGGAAGAACAACACGCCTATGC TTGTGACATAGATCCTAATAAAAAAAAATATTATGTACTTGAAATGTGGCCTTACCCTTCTGGAAACATTCATATGGGAC ATGTCAGAAATTATTCTATAGGTGATGTTATTGCCCGTATTAAAAGAATGCAAGGATATAATGTCCTTCACCCTATGGGA TGGGATGCTTTTGGTCTTCCAGCAGAACTTGCTGCAATAAAACATCATACACAACCTGCAGATTGGACGTATACAAATAT TAATGAAATGCGTGCCCAACTGAAAAGATTAGGGTATTCATATGACTGGCAAAGAGAAATAGCAACATGTGATCCTGACT ATTATCAATGGGAACAACTTTTTTTTGTTGACTGCTTTGAAAAAGGACTAGTTTATCGAAAAAAAGCTCCTCAGAACTGG TGTCCATCTTGCAATACTGTACTAGCAAATGAACAAGTTATTGAAGGAAGTTGCTGGAGATGTGATACATCTATTATTCA AAAAGAACTAACACAATGGTTTTTAAAAATTACAGATTATGCTGAAGAGCTATTAGATGATCTTACAACTCTTAAATATT CCTGGCCAGATCGTGTTATAACTATGCAAGAAAATTGGCTTGGGAAATCCACAGGTGTAGAAATTTCTTTTCCTATTGAA TCCTCTCAAGACTTCATTACTATTTTCACAACACGACCTGATACAATTTTTGGAGCAACAGCTATTATTCTTGCTCCAGA ACATCCTATATTAGAAACCTTACTTAATGATACTCCGCAAAAAGAAAAACTATATAATGTTATCGAAAAAATGAGAAATA TGGATAGATTAGAACGTCAATCTAATCTACTCACAAAAGAAGGTATTTTTATTGATCGTTATTGTATCAATCCTTGTTCT GGAGATAAAATACCCATCTGGATTGGTAATTTTGTATTAGCAGACTATGGTACAGGAGCTATTATGGCTGTACCAGCCCA TGATCAACGTGATTTTGATTTTTGTAAAAAATATAATCTACCCATTTCTATTGTTATACAGCCAGATGAACTTCAAATAA ATGAACATACAATAGTTGAACCATGGACTGGTTTAGGAACGCTTATACATTCAGGGCAATTTACAGGTCTTACTAACAAA GAAGCAAAAGAAAAAATTACTCAATATCTTGAAAAGATAGGTAAAGCAACAAGGGTTGTTTCTTGGAGATTACGAGATTG GAATATCTCTCGACAACGTTATTGGGGAACACCTATCCCTATTATATACTGTAAAAACTGTGGTGTTGTTTCTGTTCCTA AAAACGAATTACCTGTTATCCTTCCCACTAATATTACCATTAATGAAGATGGAAGCTCCCCATTACCTCAAGAGTCAAGC TTCATAGATTGTATGTGCCCTCAATGTGGTGGAATTGCCAAAAGAGAAACAGACACTATGGATACGTTTGTTGATTCATC ATGGTACTTTGCTCGTTTTGTAGATCCTAAAAATACAAAACAACCATTTGATACATCAATAGCAAAATATTGGCTCAATG TAGACCAATATATTGGTGGCGTTGAACATGCTATTCTTCATCTACTATATTCTCGTTTTTTCACAAAACTTCTTAGAGAT TTAGGTTACTTACCCTCCAATATAAATGAACCATTTGCAAAATTACTTACTCAAGGAATGGTTATAAAAGATGGTTCTAA GATGTCAAAATCTAAAGGGAATATAGTTGATCCAAATCAAATGATAAATATATATGGCGCTGATACTATACGTCTTTTTT GTTTATTTGCTGCCCCTCCTGAAAGAGACTTTGACTGGAGTGACTCAGGGATTGAAGGTTCTTATAGATTTCTGCATAGA GTTTGGAGACTTTTTATTGATGTACAACCACACATACATACAACACATGCTGGTAACTCAACAGTTATAGAAACAACTAC TGCCCTTACAAAAGATGTAAAAAGAAAAGAACATATAACCATAAAAAAAGTTAGTGAAGATATAGAAAACAAATACCAAT TTAATACAGCTATTGCTTCAATAATGGAGTTTGTAAATACGCTTTATCTCTCAAAAAATGAACTTATTCTTACAGTTGAA GGGAAAAATATACTTTCATCTGCTATAGCAACTGTGCTTACTTTATTATCACCAATGACTCCTCATATTTGTGAAGAATT ATGGAGTTATTTAGGGCACTCAACGTCTATTAGTTTAGAACCTTGGCCAAAATGGGATCCCCAGGCCCTTTTAAAAGATG TTGTAACAATAGTTGTTCAAATAAATGGGAAAGTTCGAAATAAATTTGAAGTACCAATGGATCTCTCCAAAGAAGAATTA GAACACATTATTTTTAATGATACAAAGATTACTCAATACCTTGAAGGAAAAACGATTCAAAAACATATTATTATTCCAAA CAAAATCATAAATATAGTTACAACATAA Protein sequence : MIMHSNYDPNIIEKKWQRYWEEQHAYACDIDPNKKKYYVLEMWPYPSGNIHMGHVRNYSIGDVIARIKRMQGYNVLHPMG WDAFGLPAELAAIKHHTQPADWTYTNINEMRAQLKRLGYSYDWQREIATCDPDYYQWEQLFFVDCFEKGLVYRKKAPQNW CPSCNTVLANEQVIEGSCWRCDTSIIQKELTQWFLKITDYAEELLDDLTTLKYSWPDRVITMQENWLGKSTGVEISFPIE SSQDFITIFTTRPDTIFGATAIILAPEHPILETLLNDTPQKEKLYNVIEKMRNMDRLERQSNLLTKEGIFIDRYCINPCS GDKIPIWIGNFVLADYGTGAIMAVPAHDQRDFDFCKKYNLPISIVIQPDELQINEHTIVEPWTGLGTLIHSGQFTGLTNK EAKEKITQYLEKIGKATRVVSWRLRDWNISRQRYWGTPIPIIYCKNCGVVSVPKNELPVILPTNITINEDGSSPLPQESS FIDCMCPQCGGIAKRETDTMDTFVDSSWYFARFVDPKNTKQPFDTSIAKYWLNVDQYIGGVEHAILHLLYSRFFTKLLRD LGYLPSNINEPFAKLLTQGMVIKDGSKMSKSKGNIVDPNQMINIYGADTIRLFCLFAAPPERDFDWSDSGIEGSYRFLHR VWRLFIDVQPHIHTTHAGNSTVIETTTALTKDVKRKEHITIKKVSEDIENKYQFNTAIASIMEFVNTLYLSKNELILTVE GKNILSSAIATVLTLLSPMTPHICEELWSYLGHSTSISLEPWPKWDPQALLKDVVTIVVQINGKVRNKFEVPMDLSKEEL EHIIFNDTKITQYLEGKTIQKHIIIPNKIINIVTT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 6e-149 | 41 |
