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Name : clpB (LI0126) Accession : YP_594504.1 Strain : Lawsonia intracellularis PHE/MN1-00 Genome accession: NC_008011 Putative virulence/resistance : Virulence Product : ATPases with chaperone activity, ATP-binding subunit Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 155540 - 158173 bp Length : 2634 bp Strand : + Note : - DNA sequence : ATGGATGTGAATAAGCTCACACAAAAGTCTCAAGAAGCATTATCAGAAGCACAAAGACTTTCTGCTCAATATGGGCATCA GGAAGTAGATGTAGAACATTTAGCATTGGCACTTACCATACAAGAGAATGGTTTTGTTCCAAGGGTTCTTGAACAAGCAA AAGTACATGTAAAAGTTGTGATTTCAGCATTAGAAGAAGTATTAAAAAAGCGTCCTTCTGTTCGTGGGCCTGGAAGTGAG ATGGGGAAAATTACTATCTCTCAAAGGCTAAGTAAAGTTATTGCCAATGCTGAATTATTAGCAAAACGATTGGGTGATGA GTATGTAAGTGTTGAGCATCTTTTTGCTGAATGTCTTAATGAGCCAGAGTCAACAGGAATGGGACAAGTTGCAAAAGAGA TACACCTTACGTCACAAAGATTTATAGAAGTTATGTTAGCTGTGCGTGGGCCACACCGTGTTACATCTCCTACTCCAGAA GATAGTTACGAAGCATTAAAAAAATATGGAAGAGATCTTGTAGAAGCTGCTCGAAAAGGAAAGCTTGATCCTGTAATTGG ACGGGATGCTGAAATCCGTAGAGTTATCCGAATTCTTTCTCGTAGAACAAAAAATAATCCTGTGCTTATTGGTGAAGCTG GAGTTGGGAAAACAGCTATAGTAGAAGGATTAGCTTTTCGTATCGTTCAAGGAGATGTTCCTGAAGGTTTAAAAGATAAA TCTATTTTTGCTCTTGATATGGGGTCACTGATTGCTGGAGCAAAGTACAGAGGAGAATTTGAAGAACGTCTTAAGGCTGT TTTAACAGAAGTCGAGAAGTCAGAAGGAAGAATTGTTCTTTTTATTGATGAATTACATACTATTGTTGGAGCAGGAAAAG CTGATGGAGCTATGGATGCAGGGAACTTTTTAAAACCTATGCTTGCTCGTGGAGAGCTCCATTGTATTGGTGCTACAACA TTGGATGAGTATAGAAAGTATATAGAAAAAGATCCTGCATTAGAGAGACGTTTTCAACCAGTGATGGTAGATGAACCTTC TGTTCAAGACACTATATCTATTTTACGAGGATTAAAAGAACGCTTTGAAGTTCATCATGGTGTGAGGATTAGTGATTCTG CTATAGTTGAAGCTGTAGTCCTTTCAGATAGATATATCTCAGATCGTCAACTACCAGACAAAGCAATTGATTTGATTGAT GAAGCTGCAGCTATGATCCGTACAGAAATCGACTCTCTTCCATCTGAGCTTGATGAAGTTAATCGTAAAATTATGCAGTT AGAAATAGAAAGAGAAGCCCTTAGAAAAGAAAGTGATTCAGCATCTCATGAAAGATTAGTACGTTTGGAAGAAGAATTAA AAGTACTGCAATCAACACAGTCTGAATTAAAAAAGCAATGGGAAACTGAAAAAGGTTCAATTGATTCTCTTCGAAACATA AAAGAACAAATTGAGCAGACACGACTTGCAATTGATGAGGCTACACGAAATGGTGAGCTAAGCAAGGCAGCAGAATTAAA ATACTCAAAACTGTTTGAATTAGAAAAACAATTAGAAGAACGTGAATCAAAGGCTGATGGTCCACGTTTACTTAAAGAAG AAGTTCGTCCAGATGATGTTGCTAATATTGTTGCTCGATGGACAGGTATACCTGTAACACGACTGTTAGAATCTGAAAAA GAAAAATTGTTACGATTGCCAGATACATTACATGAGCGTGTAATTGGTCAAGATGAGGCTGTGAATGTCATATGTAATGC TGTATTGCGTACACGTGCAGGACTTTCTGATCCAAAGAGACCACAAGGTTCTTTTATTTTTCTTGGACCTACAGGTGTTG GTAAAACAGAACTTTGTAAAGCTCTTGCAGAATCTTTATTTGATACTGAAGAAAATATGGTTCGCTTTGATATGAGTGAA TACATGGAGAAACACTCAGTAGCCAGGCTTATTGGAGCTCATCCTGGTTATGTAGGTTATGAAGAAGGTGGGCAACTTAC CAATGCTGTAAAACGTAAACCTTATAGTGTCATATTATTTGACGAAGTAGAAAAAGCACATCCTGATGTATTTAATATTT TTCTACAGTTACTTGATGATGGACGTTTGACGGATAATGCTGGCCGTACTATTAATTTTAGAAATACTATTATCATTATG ACTTCAAATATAGGCGCATATAAATTACTTGAAGGTATTAGTCCTGATGGTTCTTTTCATGAAGGTGTATATGAGTCTGT TATGGGTGATTTGAAACAACATTTTAGACCAGAATTTCTTAACCGAGTTGATGATGTTGTACTTTTTAAACCACTTCTGG CTGATCAAATAAGTAGTATTATAGACTTACAGTTAAGGAGTTTAAAAAAACGCCTAGAGTCACAGAAAGTTACATTAGAA TTAACACATTCAGCACATTTATATCTAGCTGAGAATGGATATGATCCTCATTATGGAGCACGTCCATTAAAAAGATACCT TCAACGAGTAGTGGAAACACCTTTAGCAAAGATGATTATTAGTGGTAAAGTTCATGAAAATCAACAGATTGTTATAGATT ACTCAGAAAGTGATTCTTCTTTACAATATGGTGTGAAAAGTGCATCTGAAGATATCAACTGGGTTCAAGTATAA Protein sequence : MDVNKLTQKSQEALSEAQRLSAQYGHQEVDVEHLALALTIQENGFVPRVLEQAKVHVKVVISALEEVLKKRPSVRGPGSE MGKITISQRLSKVIANAELLAKRLGDEYVSVEHLFAECLNEPESTGMGQVAKEIHLTSQRFIEVMLAVRGPHRVTSPTPE DSYEALKKYGRDLVEAARKGKLDPVIGRDAEIRRVIRILSRRTKNNPVLIGEAGVGKTAIVEGLAFRIVQGDVPEGLKDK SIFALDMGSLIAGAKYRGEFEERLKAVLTEVEKSEGRIVLFIDELHTIVGAGKADGAMDAGNFLKPMLARGELHCIGATT LDEYRKYIEKDPALERRFQPVMVDEPSVQDTISILRGLKERFEVHHGVRISDSAIVEAVVLSDRYISDRQLPDKAIDLID EAAAMIRTEIDSLPSELDEVNRKIMQLEIEREALRKESDSASHERLVRLEEELKVLQSTQSELKKQWETEKGSIDSLRNI KEQIEQTRLAIDEATRNGELSKAAELKYSKLFELEKQLEERESKADGPRLLKEEVRPDDVANIVARWTGIPVTRLLESEK EKLLRLPDTLHERVIGQDEAVNVICNAVLRTRAGLSDPKRPQGSFIFLGPTGVGKTELCKALAESLFDTEENMVRFDMSE YMEKHSVARLIGAHPGYVGYEEGGQLTNAVKRKPYSVILFDEVEKAHPDVFNIFLQLLDDGRLTDNAGRTINFRNTIIIM TSNIGAYKLLEGISPDGSFHEGVYESVMGDLKQHFRPEFLNRVDDVVLFKPLLADQISSIIDLQLRSLKKRLESQKVTLE LTHSAHLYLAENGYDPHYGARPLKRYLQRVVETPLAKMIISGKVHENQQIVIDYSESDSSLQYGVKSASEDINWVQV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 5e-99 | 41 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 1e-95 | 41 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 2e-95 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_594504.1 | ATPases with chaperone activity, ATP-binding subunit | VFG2076 | Protein | 6e-118 | 42 |
