Gene Information

Name : serS (LI0114)
Accession : YP_594492.1
Strain : Lawsonia intracellularis PHE/MN1-00
Genome accession: NC_008011
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 144414 - 145688 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGTTGTTAGATCTTAAATTGTTACAAAAAAAACCTGAAATAGTGTCAACTGCACTTATTCATAGAGGATCTCCACTTAA
TATAACAAGTTTTGAAGAGCTTGATACTAAACGGCGTGAACTTCTTTCTGAAGTTGAAACTCTTAAGGCTAAACGTAACC
AAGCTTCTATTCAAGTTGCACAAATGAAGCGTAATGGTGAAAATACAAATACTATTATTGCAGAACTTTCTGAACTTTCG
TCAAAAATTGTTGTATTAGACAATATGATAAATCAAGTAAAAAATGAACTCTATGACTGGATGCTTGCTGTCCCTAATAT
CCCACACTACAGTGTTCCAATTGGAAAAGATGAAACTGATAATAAAGAAATATATAGATGGGGTGAAATACCTATATTTG
ATTTTCAACCAAAGGAACATTGGGAACTAGGTTCCACTCTTCAAGGATTAGACTTTGAACGAGCAAGTAAAATTACAGGA
AGTCGTTTTACAATACTATGGAAATGGGCAGCTCGACTTGAGCGTTCATTAATTAATTTTTTTCTTGATTTTCATCTAGC
CCAAGGCCGTACAGAAGTTCTACCCCCACTCATTGTTAATGAAAAATCAATGACAAATACAGGTCAACTACCAAAATTTG
CAGATGACCTTTTTAAACTAGAAGGAACAGACTATTTTTTGATTCCTACTGCAGAAGTTCCTCTTACAAATATACACTCT
GACGAAATTATTGATGAATACCTATTACCTCTATCTTACTGTGCTCAAACAGCATGTTTTCGTTCAGAAGCAGGTTCTGC
AGGTAAAGATACAAAAGGACTTATTCGACAACACCAATTTACAAAAGTTGAAATGGTCTATTTTTCTCATCCAGATCAAT
CCTATGATCTTTTGGAACAAATGAGGAAAAGTGCTGAAACATTATTGGAACAACTTGAACTTCCTTATAGAACAGTTGTT
CTGTGCACTGGTGATCTAGGGTTTTCTTCAAGTAAAACATATGATATAGAAGTTTGGCTTCCTGGACAAAACACATATAA
AGAAATATCTTCATGTTCTAACTGCGAATCTTTTCAGGCTCGACGAGCTAATATTCGTTTTCGTGCCTCTTCTGGAGAAA
AAACACAGTTTGTCCATACACTAAATGGCTCTGGGTTACCCATTGGACGTACCATTGTTGCTATCTTAGAAAATGGTCAA
CAAAAAGATGGCTCTGTTAAACTTCCTAAAAAACTTGTTCCATATATGGGAGGCATAGAGTGTATTGAGCCATAG

Protein sequence :
MLLDLKLLQKKPEIVSTALIHRGSPLNITSFEELDTKRRELLSEVETLKAKRNQASIQVAQMKRNGENTNTIIAELSELS
SKIVVLDNMINQVKNELYDWMLAVPNIPHYSVPIGKDETDNKEIYRWGEIPIFDFQPKEHWELGSTLQGLDFERASKITG
SRFTILWKWAARLERSLINFFLDFHLAQGRTEVLPPLIVNEKSMTNTGQLPKFADDLFKLEGTDYFLIPTAEVPLTNIHS
DEIIDEYLLPLSYCAQTACFRSEAGSAGKDTKGLIRQHQFTKVEMVYFSHPDQSYDLLEQMRKSAETLLEQLELPYRTVV
LCTGDLGFSSSKTYDIEVWLPGQNTYKEISSCSNCESFQARRANIRFRASSGEKTQFVHTLNGSGLPIGRTIVAILENGQ
QKDGSVKLPKKLVPYMGGIECIEP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-105 54