Gene Information

Name : hemC (LI1011)
Accession : YP_595386.1
Strain : Lawsonia intracellularis PHE/MN1-00
Genome accession: NC_008011
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 1246200 - 1247129 bp
Length : 930 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAAAAGATCACTATTGCTACAAGAGGAAGTAAATTAGCTTTTTGGCAGGCTAACTACATTAAAGATCAATTACAAAA
AATGTATTCTTATCTTGAAGTAGATTTAATGGTTATTAAAACAAAAGGTGATCATATTCTTGATGTTCCACTGGCAAAAG
TTGGAGGAAAAGGTCTTTTTGTTAAAGAAATTGAAGAGGCTCTTTTATCTGGAGAGGCTGATTGTGCAGTTCATAGTATG
AAAGATGTCCCTATGGAGTTACCTTTTGAACTTTGTTTAGCTGCTATTACAGAACGCGAAGATCCTACAGATATGTTTCT
TTCTATAAAGTATAGTGGTGTTAAAAGTCTACCTGAAAATGCATTAGTGGGGACAAGTAGTCTGCGAAGGCAAGCACAAC
TTTTAGCATTACGGCCAGATCTTCAAATTATACCATTAAGAGGTAACATTGATACTAGACTACGGAAACTTATGGCAGAA
GAGTTTGATGCAATTATTATGGCAACTGCAGGAATAAAACGTTTAGGCCTTATAGCACCATATATGTCCTCATTGCCTTG
TAGTGTTATGCTTCCTGCTGTTGGTCAGGGAGCCCTTGGGATAGAAGTTCAAAAAGAAAGACAAGATGTATTGGAGCTAT
TTTCTTTTTTAAATCATAAAGAGACATATCATTGTATTCAAGCTGAGAGAGACTTTTTAGCAGGCCTTGATGGTGGATGT
CAGGTTCCTATTGCAGGTTATGCTACTATTTGTAAACAAGAAACTATCTGCTTAGAAGGTTTAGTTGCTAAGAGTGATGG
TTCTGTTATGATCCGTAACCGGTTAGAAAGATCAGTAAGTGATGCATATGATATTGGTATGACATTATCAAAAATACTTC
TTGCTGAAGGTGCGGATGATATTCTTGCATCAATGCATACTATCCTGTAA

Protein sequence :
MKKITIATRGSKLAFWQANYIKDQLQKMYSYLEVDLMVIKTKGDHILDVPLAKVGGKGLFVKEIEEALLSGEADCAVHSM
KDVPMELPFELCLAAITEREDPTDMFLSIKYSGVKSLPENALVGTSSLRRQAQLLALRPDLQIIPLRGNIDTRLRKLMAE
EFDAIIMATAGIKRLGLIAPYMSSLPCSVMLPAVGQGALGIEVQKERQDVLELFSFLNHKETYHCIQAERDFLAGLDGGC
QVPIAGYATICKQETICLEGLVAKSDGSVMIRNRLERSVSDAYDIGMTLSKILLAEGADDILASMHTIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-65 55
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-65 55