Gene Information

Name : LI0989 (LI0989)
Accession : YP_595364.1
Strain : Lawsonia intracellularis PHE/MN1-00
Genome accession: NC_008011
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1218216 - 1218980 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGTCAAATATCCCCTTTATACTATGGAATAATTCCTGCTAGATACGGTTCTTCACGTCTTCCTGGGAAACCATTAAT
AGATATTTGGGGAAAACCTATGTTTTGGTATGTATATCAGAATGCAGTAGAATCTAATATTTTTAGATCTGTTGTATTAG
CAACAGATAGCGAAGAAATTGCTGAATCAGCCCATCAGTTATCAATTCCTTATGTTATGACAAGTGTTGAACACATTAGT
GGTACAGATCGTGTGTATGAAGCAGCTATAAAGATGAATATAGAACCTGACTCTGTAGTAGTAAATATCCAGGGAGATGA
ACCATTAGTAAAGCCAGAAGCTATTCAACAACTAGTGGAGCCATTTATTGATGTTTCTATTCAGGTTACTACCCTTTCTA
CAAGAATTACAGCAAATCAAGCAATGTTACCTCATCAAGTTAAAGTTGTTGTGTCTTCTAATGGTGATGCTTTGTATTTT
TCAAGGGCAGCCATTCCTTATTTAAGAGATAACGATACTGATGGATATTACTTAGGTCATATTGGGTTATACGCTTTTCG
TATGCATACGTTGGATAAATTCGTTCATTTGCCACCGTCCCAATTAGAACAATTTGAAAAGTTAGAACAACTAAGGTTGC
TAGAGAATAATATACCAATTCGTGTAGTAAACACTAACCATACTTCTCAGGGTGTTGATACAGTAGAAGATTTAGAAATT
GTTCAAGGATTATTAGCTCAAAGAATGGAGGCAGTAAGTCGTTAA

Protein sequence : 
MSQISPLYYGIIPARYGSSRLPGKPLIDIWGKPMFWYVYQNAVESNIFRSVVLATDSEEIAESAHQLSIPYVMTSVEHIS
GTDRVYEAAIKMNIEPDSVVVNIQGDEPLVKPEAIQQLVEPFIDVSIQVTTLSTRITANQAMLPHQVKVVVSSNGDALYF
SRAAIPYLRDNDTDGYYLGHIGLYAFRMHTLDKFVHLPPSQLEQFEKLEQLRLLENNIPIRVVNTNHTSQGVDTVEDLEI
VQGLLAQRMEAVSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-42 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-42 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-42 43