Gene Information

Name : guaA (Acid345_1793)
Accession : YP_590868.1
Strain : Candidatus Koribacter versatilis Ellin345
Genome accession: NC_008009
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2172757 - 2174304 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGACACCCAATCAATCGTCATCCTCGACTTCGGTTCGCAATATACCCAGCTGATTGCGCGCCGCATCCGTGAACAGAA
CGTCTTCTCGGTTGTCCTTCCGTGCACCGCTAAGCTCGACGAAATCCAGAAATACAATCCTGCCGCGATCATTCTCTCGG
GCGGACCTTCGTCGGTTTACGACGCCGATGCGCCGCCGGCCGATCCGCAGGTGCTGCACCAGGGCCTGCCAGTGCTCGGC
ATCTGCTACGGCCTGCACTGGATGACCCATAATCTCGGCGGCAACGTGCGTCCGGGCGCGAAGCGCGAGTACGGCCACGC
CGAAGTCGAGATCGTCAAAGACTCGCCGCTCTTCGCGCACCTCACCGGACCGCTACAGGTCTGGATGTCGCACGGGGATG
AGGCCGACAAACTTCCAGATGGCTTCACGCTCTTTGCGCAGTCTCCGAACGCTCTCGCCGGAATGCATAATCTCGAAAAG
AACTGGTACGCGATCCAGTTCCATCCGGAAGTTCACCACACCCGGCAGGGAACTGAGATCCTTCGCAACTTCCTCTTCGA
GATCGTCAAGATCAAGCCTAACTGGACGCCCGCGCGCTTCATCGACGAAACCGTCGAGTCCATCCGCAAACAAGTGGGCG
ATGGCCACGTGATTTGCGGCCTCTCCGGCGGCGTTGATTCTTCGGTCGCCGCAACCCTCGTCCATCGCGCCATCGGCAAG
CAGCTCACCTGCATCTTCGTGAACAACGGCGTGCTGCGCATGAACGAGTTCGAGAGCGTGCAGACCAACCTGCGCGACAA
ACTTGGCCTCAACATCGTCGGCGTGGATGCCACCGATCGTTTCCTCGGTAAACTCGCCGGCGTCACTGAGCCGGAGAAGA
AGCGCAAGATCATCGGCAACGAATTCATCGCGGTCTTCGAAGAAGAAGCGCACCGCATCGAACAAGAAAGCGGCAAGGTC
GACTGGCTCGTGCAAGGCACGCTCTATCCCGATGTCATCGAGTCACAGTCGGTGCGTGGCCCGTCGCAGGTTATCAAGAG
CCACCACAACGTCGGCGGCTTGCCGGAGAAAATGAAGCTCAAGCTGATCGAGCCATTGCGCGATCTGTTCAAAGACGAAG
TGCGCCGCATTGGCCGCGACCTCGGCATGCCGGAAGACGTGCTCAATCGCCAGCCCTTTCCTGGTCCCGGACTTGCGGTT
CGCATCCTCGGCGAAGTCACCGCCGACCGGGTTGCGCTTCTGCAGAAGGCGGACCACATCGTGGTCAGCGAGATCAAGCG
TGCCGGACTCTACAACAAAATCTGGCAGTCATTCGCGGTGCTGCTTCCAGTGATGTCCGTGGGCGTGATGGGCGACCAAC
GAACATACGCGTACACCTGCGCGATTCGCAGCGTTCACTCGGAAGACGGCATGACTGCCGATTGGGTCCCGCTCCCGTAC
GACGTGCTGAAGGCGATGAGCAATCGCATCGTCAACGAGGTGAAGGGAATCAACCGCGTGGTTTACGACATCACGTCGAA
ACCGCCGGGAACGATTGAGTGGGAGTAG

Protein sequence :
MDTQSIVILDFGSQYTQLIARRIREQNVFSVVLPCTAKLDEIQKYNPAAIILSGGPSSVYDADAPPADPQVLHQGLPVLG
ICYGLHWMTHNLGGNVRPGAKREYGHAEVEIVKDSPLFAHLTGPLQVWMSHGDEADKLPDGFTLFAQSPNALAGMHNLEK
NWYAIQFHPEVHHTRQGTEILRNFLFEIVKIKPNWTPARFIDETVESIRKQVGDGHVICGLSGGVDSSVAATLVHRAIGK
QLTCIFVNNGVLRMNEFESVQTNLRDKLGLNIVGVDATDRFLGKLAGVTEPEKKRKIIGNEFIAVFEEEAHRIEQESGKV
DWLVQGTLYPDVIESQSVRGPSQVIKSHHNVGGLPEKMKLKLIEPLRDLFKDEVRRIGRDLGMPEDVLNRQPFPGPGLAV
RILGEVTADRVALLQKADHIVVSEIKRAGLYNKIWQSFAVLLPVMSVGVMGDQRTYAYTCAIRSVHSEDGMTADWVPLPY
DVLKAMSNRIVNEVKGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-134 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-127 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-127 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-127 52