Gene Information

Name : leuS (Acid345_1328)
Accession : YP_590404.1
Strain : Candidatus Koribacter versatilis Ellin345
Genome accession: NC_008009
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1602517 - 1605087 bp
Length : 2571 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACAGACGAAACTCAAATGACCGAAACTCCGAAAGCCGAAGAGCGCCCTGATCGCTACGATCCGCGGGCGATCGAAGA
GAAGTGGACCGTCCAGTGGGCGAACGATCCCGAGCTGTACGCCAGCGAGCCCGATAGCGCGAAGAAGAAGTTCTACGTCC
TTGAGATGCTGCCCTATCCCTCCGGCGCTCTCCATATGGGACACGTGCGCAACTACGCCATCGGCGACGCCCTAGCGCGT
TTCATGTGGATGACTGGCCACAACGTCCTGCACCCCATGGGTTGGGACGCCTTCGGCTTGCCCGCCGAAAACGCGGCGAT
CAAGAACCAGCGCCAGCCCCGCGAGTGGACGCTTGGCAACATCGAGGCGATGAAGAAGCAGATGCGCCGCCTCGGCTTCG
CCTACGACTGGTCGAAGGAAATCGCGACATGTTTGCCCGATTACTATCGCTGGAACCAGTGGTTCTTCATCAAGTTCTTT
GAGAAGAACCTCGCATACAAGCGCAAGAGCAAGGTGAACTGGTGCCCCGAGTGCGCCACTGTGCTCGCCAACGAGCAGGT
GGTTGACGGCTGCTGCTGGCGCCATGAAACCACGCGCGTCGAGCAGCGCGAGTTGGAGCAATGGTTCTTCCGCATTACCG
ATTACGCCGACGAACTCTTGCGCGATCTCGACCAGCTCGAAGGCTGGCCGGAAAAAGTAAAGACGATGCAGCGCAACTGG
ATTGGCCGCAGCGAAGGCGCACTTGTCACCTTCAAGCTTGAGCAACCGTCCGGCCCCAGCGGCGACAGCATCACCGTTTT
CACCACCCGCATCGACACCATCTTTGGCGCGACCTCGTTGCAGTTGGCGCCCGAACACCCGATCGTCACCGACTTGATCG
CGAGCAATCCCGATTTGCTCTCTGCCGTCGAAGACCTCAAGCAGCAGCAACGCACGGCAAAAGAAAAGGGCGATATCGGC
GCCATTGAAAAGCACGGCGTCTTTACCGGCGCATATGCCATCAATCCGTTCAATGAAGAGAAGGTGCCCATCTGGATCGC
GAACTACATCCTCACGGATTACGGCACCGGCGCGATCATGAGCGTTCCGGCACATGACGAACGTGACTACGAATTCGCCA
CGAAATACGGCCTCGAAGTTCGCGTCGTGATCTTGCCGCGCCGCGTGGGCGAGCCGCCTGAGGCCGGAAAGCCCGAAACC
AACGTGCTGCCCTACAGTGGCACCGACAGCTTGCTCATCAACTCCGGCGACTTCACGGGCCTGCCCGTGCAGGAAGCCTT
GGAGAAGATGGCCAAGTTCGCCGAAGAACACGGCTTCGGCAAAGCCACCGTCACCTTCCGCCTGAAGGATTGGGGCATCA
GTCGCCAGCGTTACTGGGGCACGCCCATTCCCATGCTCTATTGCGGCAAGTGCGGAATTGTGCCGGTGCCGGAAGATCAG
TTGCCGGTGTTGTTGCCGGAGAACGTGGAGATCACCCTCGCCGGCGGTTCGCCGCTCACGCGCGTGCAGGAGTGGCTGCA
CACCACGTGTCCGAAGTGCGGTGGCCCCGCCACGCGCGACACCGACACCATGGACACGTTCGTCGATTCGTCCTGGTACT
TCTATCGCTATACCAATCCGCAGCTCACCACTGCGCCGGTGGATACCAAGACGATTGATTACTGGTTCCCAATCGATCAG
TACATTGGCGGCGTCGAGCACGCGATCTTGCATTTGATTTACTCGCGCTTCTGGACGAAGGTCATGCGCGACTTGGGATT
GGTGCACAACAGCGAGCCGGTCACGCGCCTGTTCACGCAGGGCATGGTGATCAAAGACGGCGCGAAGATGTCGAAGAACC
TCGGCAACGTTGTCGCGCCGGATGACATGATCGCGAAGTACGGCGCTGACGCGACGCGCATGTACACGTTGTTCGCCGCG
CCACCCGATCGCGATCTCGATTGGCAGGATGCCGGCGTCGAGGGCGTGAGCCGCTTCCTCGCGCGCGTCTATCGCTTGAT
CGCGCAGAACCCCATTGTTCATGCGGGCCCCGCGCACTACACGCTTGCCGAGCTTCCAGCTAACGCAAAGAAGATCGCGC
GCAAATTACATCAGACGATCAAGAGAATTTCGGATGAGCTTGGAGGGCGGTGGCACTTCAATACTTGCGTGGCGGCACTC
ATGGAATTTGTGAACGAGTGCTATGCCGCGCCGGAGTTGTTTGCCAATCCGAAAGAGGGAATCGAGCGCACGTTGGTTGC
GGATGTGCAGCGCAAAGTCACGTTGCTGTTGCAGCCGTTCGCGCCGTACGTGGCGCATGAGTTGTGGGCGATGCTCGGTG
AACCTTCGGGATTGTTGAGAGCGCCGTGGCCCGCATTTGACGCGAGTTTGGCGAAGGAAGATGAAGTTGAGATCGTGGTG
CAAGTGAACGGAAAAGTTCGTAGCAAGCTGGTGGTTTCGACGGATGCTTCAGAAGACGAAGTGAAGAAGCTGGCGCTGGC
GGATGAAAAAGTTCAGGCGGCGATTGCTGGGAAAGAGATTGTGAAGGTCGTGGTGGTTCCGCGGAAGCTGGTCAGTATCG
TGGTGAAGTAG

Protein sequence :
MTDETQMTETPKAEERPDRYDPRAIEEKWTVQWANDPELYASEPDSAKKKFYVLEMLPYPSGALHMGHVRNYAIGDALAR
FMWMTGHNVLHPMGWDAFGLPAENAAIKNQRQPREWTLGNIEAMKKQMRRLGFAYDWSKEIATCLPDYYRWNQWFFIKFF
EKNLAYKRKSKVNWCPECATVLANEQVVDGCCWRHETTRVEQRELEQWFFRITDYADELLRDLDQLEGWPEKVKTMQRNW
IGRSEGALVTFKLEQPSGPSGDSITVFTTRIDTIFGATSLQLAPEHPIVTDLIASNPDLLSAVEDLKQQQRTAKEKGDIG
AIEKHGVFTGAYAINPFNEEKVPIWIANYILTDYGTGAIMSVPAHDERDYEFATKYGLEVRVVILPRRVGEPPEAGKPET
NVLPYSGTDSLLINSGDFTGLPVQEALEKMAKFAEEHGFGKATVTFRLKDWGISRQRYWGTPIPMLYCGKCGIVPVPEDQ
LPVLLPENVEITLAGGSPLTRVQEWLHTTCPKCGGPATRDTDTMDTFVDSSWYFYRYTNPQLTTAPVDTKTIDYWFPIDQ
YIGGVEHAILHLIYSRFWTKVMRDLGLVHNSEPVTRLFTQGMVIKDGAKMSKNLGNVVAPDDMIAKYGADATRMYTLFAA
PPDRDLDWQDAGVEGVSRFLARVYRLIAQNPIVHAGPAHYTLAELPANAKKIARKLHQTIKRISDELGGRWHFNTCVAAL
MEFVNECYAAPELFANPKEGIERTLVADVQRKVTLLLQPFAPYVAHELWAMLGEPSGLLRAPWPAFDASLAKEDEVEIVV
QVNGKVRSKLVVSTDASEDEVKKLALADEKVQAAIAGKEIVKVVVVPRKLVSIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-161 43