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Name : cadA (Rmet_2303) Accession : YP_584451.1 Strain : Cupriavidus metallidurans CH34 Genome accession: NC_007973 Putative virulence/resistance : Resistance Product : lead/cadmium-transporting ATPase Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : 3.6.3.- Position : 2523182 - 2526136 bp Length : 2955 bp Strand : + Note : - DNA sequence : ATGATGGCATCCGGGGAAAACCTTGTCAATGAAGAGCGATCTATGAACAAAGAACCTTCCAGCCCATGCGCCTGCTCCGG CGGCAATGGCCAACAGACGGCGTGCGCCAGTGAGCAGGCCAGCACTGAAACCACCGTTTTCCACGTGAGCAACATGGATT GCCGCAATGAGGAAGCACTGGTGCGGCGAACGCTGGAGGGCATGCCCGGTGTCGAGCGGCTCCTGTTCGATCTTCCGCAG CGTTTGTTGACCATTTCGCACCGCGAAGTCTCGGCCGATGCCTTGGAGCAAGCGCTGAATTCGGTGGGCATGAAGGCTCA GGCTGTCCGAGACGCCGCCGTGTCGACCACCTACCGCATCGAGAACATGGACTGCCCGAGCGAGGAGAAACTCATCCGCT CGCACCTCGGGGCAGTCGAGGGAATTCAGGACCTCGACTTCGACCTCGCTGAGCGCACCCTGTCGGTGAAACACCTCGCT CAGGCACGCGCGCAGATGGAGCAGGTCCTGGCCTCGATCGGCATGCGCGCCAAGGAGCAGACCTTCGGCCACACGGGGCC GATCGAAGCCGCGGCTGTGATCCCATCCTCGGCCCTGCAGCAGCAACCAACCGCTGCCGTTTCCGCGCCGCCGATCGGCG AGCGGGTGACGTACCGGATCGAGAACATGGATTGCCCGACGGAAGAAGCGCTGATCCGCGACCGGCTGGGCAAGCTGCCG GGTGTGACCGCGCTCGACTTCAATCTGATGCAGCGTGTGCTGGGAGTCCAGCACACGCTGGCGACCTCAGCGCCGATCGA GAAGGCGCTTGCTTCCATTGGAATGCAGGCTGCGCGGCAGGACATGCAGACAGCCACCACGGTACTTCGCATCGCGAAGA TGGACTGTCCGACCGAGGAAAGTCTGATCCGCGGCAAGCTGCAAGGCATGCCGGGCGTGCAGGGAATGGATTTCAACCTG ATGCAGCGCACGCTCACGGTTCGGCACACACCCGACGCGATCAAGCCGGCAGTCGAAGCCATCGAATCGCTGGGCATGGA AGCCGAGGTCCAGAGGACTGATGAGCCGCGCGATGCCCCGGTGGCCGCGCACAAGACCAATTGGTGGCCGATGGCGGTTT CGGGCGTTGCGGCGGTGGCCGCCGAAGGCGTGTACTGGGTCAACGACGGCAATCATTGGGCCGTGATCGTGCTGGCACTG GTTTCGATCTTCACCGGCGGCCTCAGCACCTACAAGAAGGGCTGGATCGCGCTGAAGAACCTCAACCTGAACATGAACGC CCTGATGGCCATCGCGGTCACCGGCGGCATGGCGATCGGCCACTGGCCGGAGGCCGCCATGGTCATGTTCCTGTTCGCGT TGGCGGAAGTGATCGAGGCGAAGTCGCTGGACCGCGCCCGCAACGCCATTCGGGGGCTGATGGACTTGGCGCCCGAGACC GCGACCGTGCGGCAGGCCGATGGCTCATGGACAGAGCTGCCGGCCAAGGAGGTCGCAAAGGGCGCGGTGGTCCGCGTGCG TCCTGGCGAGCGCATCGCACTGGACGGCCTGATCACCTCGGGTCGATCGGCCATCAACCAGGCGCCCATCACCGGCGAGA GCCTGCCCGTCGAGAAGGCCGAAGGTGACCAGGTCTTCGCCGGAACCATCAATGAGACCGGCTCTTTCGAATACAAGGTG ACCGCAGGCGCCAGCGACTCGACGCTCGCGCGCATCATCCATGCCGTGGAGTCCGCGCAGGGCAGCCGTGCGCCCACGCA GCGCTTCGTCGACCAGTTCGCCCGCGTCTACACGCCGGCGGTGTTCGCGGTGTCCGTGCTGGTTGCCGTCGTGCCGCCGC TCGCCTTCGGCGGCGCATGGTTTGACTGGGTCTACAAGGCCCTGGTACTGCTGGTGATCGCCTGCCCCTGCGCTCTGGTC ATCTCCACGCCGGTCACCATCGTCAGCGGCTTGGCCGCTGCCGCCCGACGCGGCATCCTGATCAAGGGTGGCGTCTACCT GGAGGGCGGGCGCAAGCTCAAGGCGTTGGCCCTGGACAAGACCGGCACACTCACACATGGCAAGCCCGAGCAGACCGACT TCGTGCCGCTGATCGGCGAGGCGCAGGAAGTTGCCGCCTGGGCCGCAAGCCTCGCGGCACGCTCGGACCATCCTGTGTCT CAGGCCATCGCCCGCAAGGCGAACCGTGACGGCATCGCGCTGCACGAGGTCGACGACTTCGCGGCGCTGCCTGGCCGCGG CGTGCGCGGCCGCGTCGCCGGGCGCATGTTGCACATGGGCAACCACAGGCTCGCCCAGGAGCTGGGCCTGAGCGAAGCGA CGCTCCAGGCTCGGCTGGAGACCCTGGAGCGCCAAGGCAAGACAGCGATCCTGCTGATGGACGATGCGACCGTGCTCGGC ATTTTTGCAGTGGCCGACACCGTGAAGGAAACCAGCCGTGAGGCGGTGGCCGACCTGCAGGCGCTGGGTGTGCGCACGCT GATGCTGACGGGGGACAACCAGCACACGGCCGCGGCCATCGCTGCCCAGGTCGGAATCTCTGAAGCCCGTGGTGACCAAC TGCCCGAAGACAAGCTCAAGACCATCGAAAGCCTGGTCGGCGGCGAGGGCCAGGTGGGCATGGTGGGCGACGGCATCAAC GATTCGCCCGCGCTCGCCCGTGCCGACATCGGCTTCGCCATGGGCGCGGCCGGCACCGACACCGCGATCGAAACAGCCGA CGTCGCCCTGATGGACGACGACCTGCGCAAGATCCCCGCCTTCATCCGGCTGTCGCGTAGCACTGCGGCGATCCTCACGC AGAACATCGTTCTGGCCCTTGGCATCAAGGCGGTGTTCCTTGCGTTGACGTTCACAGGGCATGCCACCATGTGGATGGCT GTGTTCGCTGACATGGGGGCAAGTCTTTTGGTTGTCGTCAATGGGCTGCGCCTCCTGAAGTTCAAGGCGGCATGA Protein sequence : MMASGENLVNEERSMNKEPSSPCACSGGNGQQTACASEQASTETTVFHVSNMDCRNEEALVRRTLEGMPGVERLLFDLPQ RLLTISHREVSADALEQALNSVGMKAQAVRDAAVSTTYRIENMDCPSEEKLIRSHLGAVEGIQDLDFDLAERTLSVKHLA QARAQMEQVLASIGMRAKEQTFGHTGPIEAAAVIPSSALQQQPTAAVSAPPIGERVTYRIENMDCPTEEALIRDRLGKLP GVTALDFNLMQRVLGVQHTLATSAPIEKALASIGMQAARQDMQTATTVLRIAKMDCPTEESLIRGKLQGMPGVQGMDFNL MQRTLTVRHTPDAIKPAVEAIESLGMEAEVQRTDEPRDAPVAAHKTNWWPMAVSGVAAVAAEGVYWVNDGNHWAVIVLAL VSIFTGGLSTYKKGWIALKNLNLNMNALMAIAVTGGMAIGHWPEAAMVMFLFALAEVIEAKSLDRARNAIRGLMDLAPET ATVRQADGSWTELPAKEVAKGAVVRVRPGERIALDGLITSGRSAINQAPITGESLPVEKAEGDQVFAGTINETGSFEYKV TAGASDSTLARIIHAVESAQGSRAPTQRFVDQFARVYTPAVFAVSVLVAVVPPLAFGGAWFDWVYKALVLLVIACPCALV ISTPVTIVSGLAAAARRGILIKGGVYLEGGRKLKALALDKTGTLTHGKPEQTDFVPLIGEAQEVAAWAASLAARSDHPVS QAIARKANRDGIALHEVDDFAALPGRGVRGRVAGRMLHMGNHRLAQELGLSEATLQARLETLERQGKTAILLMDDATVLG IFAVADTVKETSREAVADLQALGVRTLMLTGDNQHTAAAIAAQVGISEARGDQLPEDKLKTIESLVGGEGQVGMVGDGIN DSPALARADIGFAMGAAGTDTAIETADVALMDDDLRKIPAFIRLSRSTAAILTQNIVLALGIKAVFLALTFTGHATMWMA VFADMGASLLVVVNGLRLLKFKAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 0.0 | 100 |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 8e-114 | 41 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 6e-114 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| cadA | YP_584451.1 | lead/cadmium-transporting ATPase | BAC0298 | Protein | 0.0 | 71 |
