Gene Information

Name : ureC (Rmet_0961)
Accession : YP_583116.1
Strain : Cupriavidus metallidurans CH34
Genome accession: NC_007973
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1045698 - 1047416 bp
Length : 1719 bp
Strand : +
Note : -

DNA sequence :
ATGAGCGTGAAGATCTCCAGGCAGGCCTATGCCGAGATGTTCGGCCCGACCACGGGCGACAGGTTGCGTCTTGCCGACAC
GGACCTTGTGATCGAAGTCGAGCGCGATTTCACGATCTACGGCGAGGAAGTGAAGTTCGGCGGCGGCAAGGTGATTCGCG
ATGGCATGGGCCAGAGCCAGCGCATGTCGAAGGACTGCGTCGACACGGTGGTCACCAACGCACTGATCATCGACCACTGG
GGCATCGTGAAGGCCGATATCGGGCTGAAGCACGGGCGCATCGCGGCAATCGGCAAGGCGGGTAATCCGGATATCCAGCC
GGGGGTGACGATCATCGTCGGGCCGGGTACCGAGGTCATCGCGGGCGAGGGGATGATTGTCACCGCTGGCGGCATCGACA
CGCACATCCACTTCATCTGCCCGCAGCAGATCGAAGAAGCGCTGATGAGCGGCGTGACGACGATGATCGGCGGCGGCACC
GGGCCGGCGACGGGCACCTATGCGACGACCGTGACGCCGGGCCCGTGGTACATGGAGCGGATGCTGCAGGCGGCCGATGC
GTATCCGATGAACATCGGCTTTCTCGGCAAGGGCAACGCCAGCCTGGCGGCGCCGCTGACCGAGCAGGTGGAGGCGGGCG
CCATCGGCTTGAAGCTGCACGAGGACTGGGGCACCACGCCGCAGGCGATCGACACCTGCCTGTCCGTGGCCGATGCCACC
GATACCCAAGTGGCGATCCACACCGATACGCTCAACGAAGGCGGTTTTGTCGAGGCGACGATTGCCGCGTTCAAGGGCCG
CACGATCCATACGTATCACACCGAGGGCGCGGGTGGCGGCCACGCGCCGGACATCATCAAGGTTTGCGGCGAGGCTAATG
TGCTGCCGTCGTCGACCAATCCGACGCGCCCGTACACCGTGAACACGCTGGACGAGCACCTGGACATGTTGATGGTCTGC
CATCACCTGGATCCGGCCATTGCGGAGGACATTGCGTTCGCCGAGTCGCGCATCCGTCGCGAGACCATCGCGGCCGAGGA
CATCCTGCATGACCTGGGCGCGTTCTCGATGATCTCGAGCGATTCGCAGGCCATGGGCCGCGTGGGCGAGGTGATCATTC
GCACGTGGCAGACCGCGCACAAGATGGCCGCGCAGCGCGGCAAGTTGCCCGGCGATCCACACGATGCGCGTGGCGGGCAC
GACAACTTCCGCGTCAAGCGCTATATCGCCAAGTACACGATCAATCCAGCGCTCACGCACGGTATCGCGCACGAGGTGGG
GTCGATCGAAGTCGGCAAGTGGGCGGATCTGGTGTTCTGGAAGCCGGCCTTCTTCGGCGTGAAGCCGAGCCTGATTCTCA
AGGGCGGCATGATCGCGGCGGCGGCGATGGGCGATCCGAATGCCTCGATCCCGACACCGCAGCCGGTGCACTATCGTCCG
ATGTTCGCTTCGGCCGGCGGGGCGCTGCCGAGATCGTCGCTCACCTTCGTCTCGCAGGCGGCGCTGGCGGCGAATGTCGG
CGAGCGCTATGGCCTGGCCAAGACGCTCACCGCAGTGCGCGGCACGCGTACCGTCAGCAAACGCGACATGGTGCACAATG
ACTGGCAGCCGCACGTCACCGTGGATCCGGAGACTTACCAGGTGGTAGCCGATGGTCAGCTGCTGACGTGCGAACCTGCC
ACTGTGCTGCCGATGGCGCAGCGCTATTTCCTGTTCTGA

Protein sequence :
MSVKISRQAYAEMFGPTTGDRLRLADTDLVIEVERDFTIYGEEVKFGGGKVIRDGMGQSQRMSKDCVDTVVTNALIIDHW
GIVKADIGLKHGRIAAIGKAGNPDIQPGVTIIVGPGTEVIAGEGMIVTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGT
GPATGTYATTVTPGPWYMERMLQAADAYPMNIGFLGKGNASLAAPLTEQVEAGAIGLKLHEDWGTTPQAIDTCLSVADAT
DTQVAIHTDTLNEGGFVEATIAAFKGRTIHTYHTEGAGGGHAPDIIKVCGEANVLPSSTNPTRPYTVNTLDEHLDMLMVC
HHLDPAIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVIIRTWQTAHKMAAQRGKLPGDPHDARGGH
DNFRVKRYIAKYTINPALTHGIAHEVGSIEVGKWADLVFWKPAFFGVKPSLILKGGMIAAAAMGDPNASIPTPQPVHYRP
MFASAGGALPRSSLTFVSQAALAANVGERYGLAKTLTAVRGTRTVSKRDMVHNDWQPHVTVDPETYQVVADGQLLTCEPA
TVLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 73
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 73
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-163 62
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-163 62
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-163 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-162 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_583116.1 urease subunit alpha VFG0270 Protein 2e-157 64