Gene Information

Name : merA (Rmet_6174)
Accession : YP_581983.1
Strain :
Genome accession: NC_007971
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 127539 - 129224 bp
Length : 1686 bp
Strand : -
Note : -

DNA sequence :
ATGACCCATCTAAAAATCACCGGCATGACTTGCGACTCGTGCGCGGCGCACGTCAAGGAAGCGCTGGAAAAAGTGCCAGG
CGTGCAGTCGGCGCTGGTGTCCTATCCGAAGGGCACAGCGCAACTCGCCATCGTGCCGGGCACATCGCCGGACGCGCTGA
CTGCCGCCGTGGCCGGACTGGGCTACAAGGCAACGCTAGCCGATGCGCCACTGGCGGACAACCGCGTCGGACTGCTCGAC
AAGGTGCGGGGATGGATGGCCGCCGCCGAAAAGCACAGTGGCAACGAGCCCCCGGTGCAGGTAGCGGTCATTGGCAGCGG
TGGAGCCGCGATGGCGGCGGCGCTGAAGGCCGTCGAGCAAGGCGCGCAGGTCACGCTGATCGAGCGCGGCACCATCGGCG
GCACCTGCGTCAATGTCGGCTGTGTGCCGTCCAAGATCATGATCCGCGCCGCCCACATCGCCCATCTGCGCCGGGAAAGC
CCGTTCGATGGCGGTATTGCGGCAACTGTGCCTACGATTGACCGCAGTAAGCTGCTGGCCCAGCAGCAGGCCCGCGTCGA
CGAACTGCGGCACGCCAAGTACGAAGGCATCCTGGGCGGTAATCCGGCCATCACCGTTGTGCACGGTGAGGCGCGCTTCA
AGGACGACCAGAGCCTTACCGTCCGTTTGAACGAGGGTGGCGAGCGCGTCGTGATGTTCGACCGCTGCCTGGTCGCCGCG
GGTGCCAGCCCGGCGGTCCCGCCGATTCCGGGCTTGAAAGAGTCACCCTACTGGACTTCCACCGAGGCCCTGGCGAGCGA
CACCATTCCCGAACGCCTTGCCGTAATCGGCTCGTCGGTGGTGGCGCTGGAGCTGGCGCAAGCCTTTGCCCGGCTGGGCA
GCAAGGTCACGGTCCTGGCGCGCAATACCTTGTTCTTCCGTGAAGACCCGGCCATCGGCGAGGCGGTGACAGCCGCTTTC
CGTGCCGAGGGCATCGAGGTGCTGGAGCACACGCAAGCCAGCCAGGTCGCCCATATGGACGGTGAATTCGTGCTGACCAC
CACGCACGGTGAATTGCGCGCCGACAAACTGCTGGTTGCCACCGGTCGGACACCGAACACGCGCAGCCTCGCGCTGGACG
CAGCGGGGGTCACTGTCAATGCGCAAGGTGCCATCGTCATCGACCAAGGCATGCGCACGAGCAACCCGAACATCTACGCG
GCCGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACCCGTGCCGCGATCAACATGACCGG
CGGCGATGCGGCGCTCGACCTGACCGCAATGCCGGCCGTGGTGTTCACCGATCCGCAAGTGGCGACCGTGGGCTACAGCG
AGGCGGAAGCCCACCACGACGGGATCGAGACCGACAGCCGCACCTTGACCTTGGACAACGTGCCGCGTGCGCTCGCCAAC
TTCGACACACGCGGCTTCATCAAGTTGGTTATCGAGGAAGGCAGCCATCGGCTGATCGGCGTACAAGCGGTCGCGCCGGA
AGCGGGTGAACTGATCCAGACGGCGGCTCTGGCCATTCGCAACCGCATGACGGTGCAGGAACTGGCCGACCAGTTGTTCC
CCTACCTGACGATGGTCGAGGGGTTGAAGCTCGCGGCGCAGACCTTCAACAAGGATGTGAAGCAGCTTTCCTGCTGCGCC
GGGTGA

Protein sequence :
MTHLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIVPGTSPDALTAAVAGLGYKATLADAPLADNRVGLLD
KVRGWMAAAEKHSGNEPPVQVAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRES
PFDGGIAATVPTIDRSKLLAQQQARVDELRHAKYEGILGGNPAITVVHGEARFKDDQSLTVRLNEGGERVVMFDRCLVAA
GASPAVPPIPGLKESPYWTSTEALASDTIPERLAVIGSSVVALELAQAFARLGSKVTVLARNTLFFREDPAIGEAVTAAF
RAEGIEVLEHTQASQVAHMDGEFVLTTTHGELRADKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQGMRTSNPNIYA
AGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALAN
FDTRGFIKLVIEEGSHRLIGVQAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCA
G

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 94
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 94
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 94
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 93
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 93
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 86
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 86
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 86
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 79
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_581983.1 putative mercuric reductase BAC0652 Protein 0.0 99
merA YP_581983.1 putative mercuric reductase BAC0653 Protein 0.0 81
merA YP_581983.1 putative mercuric reductase BAC0650 Protein 2e-174 71