Gene Information

Name : thyA (Pcryo_2314)
Accession : YP_581575.1
Strain : Psychrobacter cryohalolentis K5
Genome accession: NC_007969
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 2841906 - 2842778 bp
Length : 873 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACCATGAACAGCTCTATCATTAAAAACGAGCAAGCCTATTTAGACCTGCTACGCCTTGTCCTTAATGAAGGCACTGA
AAAAGGTGACCGTACTGGAACGGGTACGCTTAGCCATTTTGGCGCGCAGCTACGTTTTAATTTAGCCGATGGTTTTCCAC
TATTAACCACCAAAAAAGTTCACTTAAAGTCCATCACCTATGAGCTCCTATGGTTTTTAAATGGTAGTACCCACGTCGAT
TATTTACAACAAAACGGCGTACGCATCTGGAATGAATGGGCAACGAGCGAGCAAACGGCGCGCTTTAATCGTCCTGCAGG
TGACTTAGGTCCTATTTATGGTCACCAATGGCGTAATTATGGCGCGACCACAACTGCAGATGGGCAGTATAACTCTGACG
GTGTCGATCAAATCGCACAAGTGGTTGAACAAATAAAAACCAATCCTAACTCGCGGCGCTTGATTGTCTCTGGCTGGAAT
CCGGGTGAAGCAGATCAAGTTGCGCTGCCACCTTGTCATACGTTATTCCAGTTTTTTGTTGCGGATAATAAACTCTCCTG
CCAACTCTATCAGCGCTCAGCGGATTTATTTTTGGGCGTACCTTTTAATATCGCAAGCTATGCCATGCTTACCCATATGG
TGGCACAAGTTTGTAATCTAGAAGTTGGTGAATTTATTTGGACCGGTGGCGATTGCCATATTTATCAAAACCACCGTGAG
CAAGTGGAGCTGCAGCTGACCCGCTCGCTTTATACGCTGCCGACATTAGCACTTAACCCTAATGTAAAAGATATTTTTGC
TTTTAATTATGAGGATATCAGCGTTGATGGCTATGAGTCTCATCCAGCGATTAAGGCACAAGTTGCGGTATAG

Protein sequence :
MTMNSSIIKNEQAYLDLLRLVLNEGTEKGDRTGTGTLSHFGAQLRFNLADGFPLLTTKKVHLKSITYELLWFLNGSTHVD
YLQQNGVRIWNEWATSEQTARFNRPAGDLGPIYGHQWRNYGATTTADGQYNSDGVDQIAQVVEQIKTNPNSRRLIVSGWN
PGEADQVALPPCHTLFQFFVADNKLSCQLYQRSADLFLGVPFNIASYAMLTHMVAQVCNLEVGEFIWTGGDCHIYQNHRE
QVELQLTRSLYTLPTLALNPNVKDIFAFNYEDISVDGYESHPAIKAQVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-79 59
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-66 50