Gene Information

Name : guaA (Pcryo_0016)
Accession : YP_579284.1
Strain : Psychrobacter cryohalolentis K5
Genome accession: NC_007969
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 20495 - 22090 bp
Length : 1596 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAACTGCTGCCAACGTTCCTACTATTAAAGAAGATCGCATCTTAATTCTCGATTTTGGCTCGCAGTACAGCCAGCT
TATCGCCCGCCGTGTCCGTGATTCAGGCGTATTCTGTGAGATGTTCCCTTATGATATCGACACTCAGCGCATCATCGATT
TTGGCGCAAAAGGCGTTATCTTATCTGGTGGTCCTGAGAGCGTCCACGCAGATGACAGCCCACGCATCAACGATGCTGTA
TTTGATATAGGCGTACCAGTATTAGGTATCTGCTATGGTATGCAAGCGATGGCAGAGCGTTTCGGTGGTAAAGTTCACGC
CAGTGATATCCATGAATTTGGCGCAGCAACCATCAATATCGATGGCAAATCAACGCTGACTGATGGTATCGAAGACGCAG
CAGCGAAGCTAAATGTCTGGATGAGTCATGGCGATAAAGTAGTCGACGCCCCACAAGGTTTCGATATCGTCGCCAGTACG
CCAAGCTGCCCGATTGCGATCATGGCAGATGATTCGCGCCATTATTATGGGCTACAGTTCCATCCTGAAGTGACGCATAC
CGCACAAGGTCAGGCATTGCTAGGACGTTTTGTCCATCAAATCTGTGACTGCGCGGGTAGCTGGACGCCTGATAACATCA
TCGATATGCGTATCGAGCAACTCAAAAAGCAAATCGGTGATAAGCAAGTATTGCTAGGTCTTTCAGGTGGTGTAGACAGC
TCAGTTGTCGCAGCATTATTGCATAAAGCCATCGGCGATCAATTAACGTGCGTGTTTGTCGATACTGGTCTGCTTCGTCT
GCATGAAGGCGATCAAGTGATGCAAATTTTTGCAGAAAACATGGGCGTAAAAGTCATTCGTGTTGATGCCGAAGAGTTAT
TCTTAACGGCATTGGCTGGCGAGTCTGATCCAGAAGCCAAGCGTAAAATCATCGGTAAAACCTTTATCGATGTATTTGCC
AATAGTGCTCGTGAAGTCAGCGAGCAGAGCGATGGTAAAGTCATCGAATTCTTAGCGCAAGGTACGATTTATCCAGACGT
GATTGAATCTGCCAAGTCGCATCAAGGTAAAGCGCACGTCATTAAGAGTCATCATAACGTTGGTGGTTTGCCAGATGATT
TAGCGTTTGAATTGGTTGAGCCGTTACGTGATTTGTTCAAAGATGAAGTACGTAAATTGGGTATTACCCTAGGTTTGCCT
GCCAAAATGATTAACCGTCATCCGTTCCCAGGACCGGGTTTGGGCGTGCGTATCTTGGGCAAAGTGACCAAAGAGTTTGC
TGATATCCTACGTTCTGCTGATGCTATCTTTATGGAAGAGCTTGAGCGTTCAGGTTGGTATGAGAAAACCGCGCAAGCAT
TTGCGGTATTCCAACCAATCAAATCGGTTGGTGTGGTCGGTGATGGTCGCCGCTATGCGTGGGTGATTGCGCTACGTGCC
GTTGAGACTGTTGACTTTATGACCGCACGCTTTGCGCATCTGCCGTATGATTTGATTGAAACGGTATCGAATCGAATCAT
GAACGAAATCGCTGAAGTTTCACGCGTGACTTATGATGTGTCGAGCAAGCCACCTGCGACGATTGAGTGGGAATAA

Protein sequence :
MTTAANVPTIKEDRILILDFGSQYSQLIARRVRDSGVFCEMFPYDIDTQRIIDFGAKGVILSGGPESVHADDSPRINDAV
FDIGVPVLGICYGMQAMAERFGGKVHASDIHEFGAATINIDGKSTLTDGIEDAAAKLNVWMSHGDKVVDAPQGFDIVAST
PSCPIAIMADDSRHYYGLQFHPEVTHTAQGQALLGRFVHQICDCAGSWTPDNIIDMRIEQLKKQIGDKQVLLGLSGGVDS
SVVAALLHKAIGDQLTCVFVDTGLLRLHEGDQVMQIFAENMGVKVIRVDAEELFLTALAGESDPEAKRKIIGKTFIDVFA
NSAREVSEQSDGKVIEFLAQGTIYPDVIESAKSHQGKAHVIKSHHNVGGLPDDLAFELVEPLRDLFKDEVRKLGITLGLP
AKMINRHPFPGPGLGVRILGKVTKEFADILRSADAIFMEELERSGWYEKTAQAFAVFQPIKSVGVVGDGRRYAWVIALRA
VETVDFMTARFAHLPYDLIETVSNRIMNEIAEVSRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-132 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-132 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-132 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-115 47