Gene Information

Name : Nham_0376 (Nham_0376)
Accession : YP_575727.1
Strain : Nitrobacter hamburgensis X14
Genome accession: NC_007964
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 414838 - 415614 bp
Length : 777 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGACCAAGACCCGCACGCTGGTGCTGATTCCGGCCCGCATGGCCGCGACCCGGCTGCCCGGGAAACCGCTGCTGGATAT
CGGCGGCCTGCCGATGGTGGTCCATGTCCTGCGGCGAGCCGAGACCGCCGGCATCGGCCGCGTCGCCGTCGCCACCGACA
CTCCCGAGATCGCGGCCGCAGTGACGGCCCATGGCGGCGAAGCAATCATGACGCGCGCCGATCATCCGTCCGGATCCGAC
CGCGTCTTCGAGGCGCTCGACCGTCTCGACCCCGACGGACGCATCGAGACGATCATCAACCTGCAGGGCGATTTCCCGAC
CATCCGCCCGGATATTATCCGCGACGTGCTTAAGCCGCTGGCCGACCCCGCGGTCGATATCGCGACGCTGGCCGCCGAAA
TCCACAGCGACGAAGAGGCCACCAACCCGAATGTCGTCAAGGCCGTGGGATCGCCGGTAGCCCCGCGGCGGCTGCGCGCG
CTCTACTTCACCCGCGCCACCGCCCCGCACGGCGACGGCCCGCGCTACCACCACATCGGGCTTTACGCCTATCGCCGCAA
AGCGCTGCAACGCTTCGTCGAACTGCCGCCCTCACCTCTTGAGCGGCAGGAAAGGCTCGAGCAATTGCGGGCGCTGGAAG
GCGGAATGCGGATCGACATCATGATCGTGGACGACGTGCCGCGGGGCGTCGATACCGCGGCCGACCTCGAAACCGCCCGC
CGCATTCTGGCTAGTGTCCCGATACCAAAGCTCGCATACCCTCGCAGCAACCTTTGA

Protein sequence :
MTKTRTLVLIPARMAATRLPGKPLLDIGGLPMVVHVLRRAETAGIGRVAVATDTPEIAAAVTAHGGEAIMTRADHPSGSD
RVFEALDRLDPDGRIETIINLQGDFPTIRPDIIRDVLKPLADPAVDIATLAAEIHSDEEATNPNVVKAVGSPVAPRRLRA
LYFTRATAPHGDGPRYHHIGLYAYRRKALQRFVELPPSPLERQERLEQLRALEGGMRIDIMIVDDVPRGVDTAADLETAR
RILASVPIPKLAYPRSNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-41 47
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-40 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-40 46