Gene Information

Name : thyA (Nham_2730)
Accession : YP_577969.1
Strain : Nitrobacter hamburgensis X14
Genome accession: NC_007964
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3008355 - 3009149 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAACCAGTACCACGATCTGCTCGAACGTATTCTCAGCGACGGCGCGGAGAAGCATGACCGTACCGGCACCGGAACATT
GTCCATCTTCGGGCATCAGATGCGTTTCAATCTCGCATCGGGATTTCCGATGCTGACCACCAAGAAGCTTCCGCTCAAGT
CGATCGTGCATGAACTGCTCTGGTTCCTGAAGGGCGAGACCAACGTCAGGTATCTGAGGGAGCACGGCGTCTCGATCTGG
GACGAGTGGGCCGACGCCAACGGCGATCTCGGCCCGGTCTACGGTTCGCAGTGGCGCTCATGGCCCGCGCCGGACGGACG
CAGCATCGACCAGATCGCCAACGTAGTCGACATGATCGGGCGCAGTCCGGATTCGCGGCGGCTGATCGTCAGCGCGTGGA
ATCCGGCCGATGTCGACAAGATGGCGCTGCCGCCGTGCCACTGCCTGTTTCAGTTCTATGTTGCCGACGGAAAACTGTCG
TGCCAGCTTTATCAGCGCTCGGCGGATGTGTTTCTGGGGGTGCCCTTCAACATCGCGTCCTATGCGTTGCTGACGATGAT
GGTCGCGCAGGTCACGGGGCTCAAGCCCGGGGACTTCGTGCACAGCCTCGGCGACGCGCACCTCTATTTGAATCACCTCG
ATCAGGCACGGCTTCAACTCACGCGGCCGACACGATCGCTGCCGACGATGACGATCAATCCCGAGGTGAAGAGTATCTTC
GCGTTCCGCTACGAGGATTTCAAACTCGAGAACTACGATCCCCATCCGCATATCAAGGCAGAGGTCGCGGTGTGA

Protein sequence :
MNQYHDLLERILSDGAEKHDRTGTGTLSIFGHQMRFNLASGFPMLTTKKLPLKSIVHELLWFLKGETNVRYLREHGVSIW
DEWADANGDLGPVYGSQWRSWPAPDGRSIDQIANVVDMIGRSPDSRRLIVSAWNPADVDKMALPPCHCLFQFYVADGKLS
CQLYQRSADVFLGVPFNIASYALLTMMVAQVTGLKPGDFVHSLGDAHLYLNHLDQARLQLTRPTRSLPTMTINPEVKSIF
AFRYEDFKLENYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-82 62