Gene Information

Name : Nham_2633 (Nham_2633)
Accession : YP_577874.1
Strain : Nitrobacter hamburgensis X14
Genome accession: NC_007964
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 2893896 - 2894780 bp
Length : 885 bp
Strand : +
Note : -

DNA sequence :
ATGTCCGGGACCGCGCAAAGCCAGCGCATGACCGCGGCAGGTTCCATATCCAGAGATATAACGGATGACACGCGTCATCC
GGTGCTGCATGGGCTGCTGTCGCGGCCATATCCGGCGGTCATGGGGGTCTTGAACGTCACCCCCGACTCGTTCTCCGACG
GTGGTCAATTCATCACGCCCGACCAGGCGCTGGCGCAGGCGCGTCGCATGATCGCGGAAGGGGCCGACATCATCGACGTC
GGTGCCGAATCCACCCGCCCCTACGGATCGCAGCCGGTCTCGCACGACGAGGAGATGCGGCGGCTGAAGCCGGTGCTGGC
CGCGGTGGTCGCGCTGGGCACGCCTGTGTCCATCGACAGCATGAAGTCGTCGATCGTTGCCTGGGCGCTCGGTAGCGGAG
CCGCGATCGCCAACGACGTCTGGGGCTTGCAGCGCGATCCGGACATGGCGCGCGTGGTCGCCGCGCACAATGCGCCCGTC
ATCGTGATGCATAACCGCGACAAGCCCGACGCCGCCCTCGACATCATGCGGGACATCGCGGCGTTCTTCGAACGATCGCT
GGAGATCGCGGCGAAAGCCGGAATCCCGGCAGGCCATGTCGTCCTCGATCCGGGCATCGGTTTCGGCAAAACGCAAGAAC
AGAGCATGATTGCGCTGGCCCGGCTCGACGAACTGCAGAAATTCGGCTTGCCGGTTCTGGTGGGCGCGTCGCGCAAGCGT
TTCATCAGCACGGTGGTGCCGTCGGAGCCGAAGGAGCGGCTTGGCGGCTCGCTCGCCGCGCATCTGATCGCAGCACGAGG
CGGTGCGCGCATCATCCGCACGCATGATGTGGCGGACACGGTGCAAGCGCTGCGCGTGGCGCAAGCCATCGATTCCAGGA
CATAG

Protein sequence :
MSGTAQSQRMTAAGSISRDITDDTRHPVLHGLLSRPYPAVMGVLNVTPDSFSDGGQFITPDQALAQARRMIAEGADIIDV
GAESTRPYGSQPVSHDEEMRRLKPVLAAVVALGTPVSIDSMKSSIVAWALGSGAAIANDVWGLQRDPDMARVVAAHNAPV
IVMHNRDKPDAALDIMRDIAAFFERSLEIAAKAGIPAGHVVLDPGIGFGKTQEQSMIALARLDELQKFGLPVLVGASRKR
FISTVVPSEPKERLGGSLAAHLIAARGGARIIRTHDVADTVQALRVAQAIDSRT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 3e-35 44
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 2e-35 44
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 2e-35 44
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 3e-35 44
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 3e-35 44
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 3e-35 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Nham_2633 YP_577874.1 dihydropteroate synthase AM180355.1.gene1650. Protein 2e-54 47
Nham_2633 YP_577874.1 dihydropteroate synthase CP001138.1.gene3456. Protein 3e-40 44
Nham_2633 YP_577874.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 2e-35 44
Nham_2633 YP_577874.1 dihydropteroate synthase NC_002695.1.916103.p Protein 1e-39 43
Nham_2633 YP_577874.1 dihydropteroate synthase CP000647.1.gene3624. Protein 7e-41 43
Nham_2633 YP_577874.1 dihydropteroate synthase NC_002516.2.881715.p Protein 1e-41 43
Nham_2633 YP_577874.1 dihydropteroate synthase CP002695.1.gene1085. Protein 2e-36 43
Nham_2633 YP_577874.1 dihydropteroate synthase NC_008702.1.4608834. Protein 1e-32 42
Nham_2633 YP_577874.1 dihydropteroate synthase CP004022.1.gene3451. Protein 3e-42 42
Nham_2633 YP_577874.1 dihydropteroate synthase CP000675.2.gene3019. Protein 2e-44 42
Nham_2633 YP_577874.1 dihydropteroate synthase CP000034.1.gene3358. Protein 2e-38 42