Gene Information

Name : Nham_1791 (Nham_1791)
Accession : YP_577065.1
Strain : Nitrobacter hamburgensis X14
Genome accession: NC_007964
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1991865 - 1993277 bp
Length : 1413 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGACATCAAAGCGATCCGCGACAACCCCGCAGCCTTCGATGCCGCGCTGAAGCGGCGGGGGCTTGCGCCGCTGTC
GTCGTCACTGCTCGCAATCGACGAGAAACGCCGCGCTGCGATTCTGGCGTCGGAGCAGGCGCAGGCGCGCCGCAACGCGG
CTTCGAAGGAAATCGGCGAGGCCAAGAAGGCGAAGGACGAGGCGCGCGCCGCGAAGCTGATGGCGGAAGTCGCCGAACTC
AAGACCTCCATGCCCGAGATGGACGCGGCGGCGAAAGCGGCCGACGAGAAGCTGAGAAAGGCGCTTGCCGAAATTCCGAA
CCTGCCGCTCGACGAGGTGCCCGATGGTACTGATGAGCACGGCAACATCCAGCATCATGTGTTCGGCAAGAAACGCGACT
ATGCGTTTACGCCGAAGCCGCATGAGGATCTCGGCGGCGCGCTCGGCGACATGGATTTCGAGGCGGCGGCAAAATTGTCC
GGCGCGCGCTTCGTGGTGCTGAAGCGGGGACTGGCGCGGCTCGAACGCGCCATCGGACAATTCTTCCTCGACGTCCACAC
TGGCGAGCACGGTTATACCGAGGTCAATCCACCGCTTCTGGTGCGTGATGACGCCATGTTCGGCACAGCCCAGTTGCCGA
AGTTTGCAGAGGATCAGTTTGATTTCATTAAAGACAGGACGATCTCCGAGCAACTTGAGCAAACAGTTGTCGAAATAGAT
CAGAGGAAGGTTAGGCCTGGTCATTTCGACATGGAGCAAAAGGTTACCCCGCTGTCGGCTCCAACACGCAAAGACAGACT
TTGGCTCATCCCCACCGCCGAAGTCCCGCTCACCAACCTCGTTCGCGAATCCATCCTCGATGAAAAAGAACTGCCGCTGC
GCTTCACCGCGCTGACGCCGTGTTTTCGCGCCGAAGCGGGCGCCGCCGGGCGCGACACCCGCGGCATGATCCGCCAGCAC
CAATTCACCAAGGTCGAACTGGTCTCGATCACGACGCCGGAAACATCCAAGGACGAACACGAGCGGATGCTCTCCTGCGC
CGAGGAAGTGCTGCGCCGGCTCGACCTGCATTACCGCGTGATGACGCTGTGCACCGGCGACATGGGCTTTGCCTCGCAAA
AGACCTATGACATCGAGGTGTGGATGCCGGGACAGGGTGAGGGCGGTGCCTACCGAGAGATTTCGTCCTGCTCGGTGTGC
GGCGATTTCCAGGCGCGGCGCATGGACGCGCGCTCGCGTGGCCCCGACGGCAAGCCACGCTTCGTTCATACGCTGAATGG
CTCCGGCACCGCGGTCGGCCGCGCCCTGATCGCCGTGATGGAGACCTATCAGCAGGCCGATGGCTCCATCGCCGTGCCCG
ACGTGCTTTTGCCCTACATGGGCGGCCTCAAGGTGATTGCGAAAGGCTTGTAG

Protein sequence :
MHDIKAIRDNPAAFDAALKRRGLAPLSSSLLAIDEKRRAAILASEQAQARRNAASKEIGEAKKAKDEARAAKLMAEVAEL
KTSMPEMDAAAKAADEKLRKALAEIPNLPLDEVPDGTDEHGNIQHHVFGKKRDYAFTPKPHEDLGGALGDMDFEAAAKLS
GARFVVLKRGLARLERAIGQFFLDVHTGEHGYTEVNPPLLVRDDAMFGTAQLPKFAEDQFDFIKDRTISEQLEQTVVEID
QRKVRPGHFDMEQKVTPLSAPTRKDRLWLIPTAEVPLTNLVRESILDEKELPLRFTALTPCFRAEAGAAGRDTRGMIRQH
QFTKVELVSITTPETSKDEHERMLSCAEEVLRRLDLHYRVMTLCTGDMGFASQKTYDIEVWMPGQGEGGAYREISSCSVC
GDFQARRMDARSRGPDGKPRFVHTLNGSGTAVGRALIAVMETYQQADGSIAVPDVLLPYMGGLKVIAKGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-81 46