Gene Information

Name : lysS (Csal_2997)
Accession : YP_575041.1
Strain : Chromohalobacter salexigens DSM 3043
Genome accession: NC_007963
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 3333942 - 3335450 bp
Length : 1509 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGCCAACCAAGACGCCGCTCAACACGACGAGAATCATCTGATCGCGGAACGCCGTGCCAAGCTGGCGGCGCGCCGCGA
CCAAGCCGCGGAAGCCGGGGGCAGCGCCTTTCCCAACGACTTTCGCCGCGACAGCCTCGCCGCCGAACTTCAGGCCGAGC
TGGGCGACAAGGACAAGGCCGAGCTGGAAACGCTCGACCGCCGGGCCTCGGTGGCCGGGCGCATCATGCGCAAGCGCGGG
CCCTTCATCGTCATTCAGGACGTCTCCGACCAGATCCAGCTCTACGTCGACAAGAAAGGGCTGCCCGCGGAGACCCTCGA
CGACATCAAGAGCTGGGATATCGGCGACATCGTCGCGGCCCGCGGGCCGGTGCACAAGTCCGGCAAGGGTGACCTCTACG
TCATGATGGGCGAGGCGCAACTGCTGACCAAGAGCCTGCGTCCCCTGCCCGACAAGTACCACGGCCTGACCGATACCGAG
GCCCGCTACCGCCAGCGCTATGTCGACCTGATCATGAACCCCGAGTCGCGTCGCGTCTTCGAGGTGCGTTCGCGTGTAAT
CAGCGGCATTCGGCGTTTTCTGGTCGAGCGCGGCTTCATGGAAGTCGAGACGCCGATGCTGCAGCAGATTCCCGGCGGCG
CCACGGCAAGGCCTTTCGTCACGCATCACAACGCGCTGGATATCGACATGTACCTGCGCGTCGCCCCCGAGCTGTATCTC
AAGCGCCTGGTCGTCGGTGGCTTCGAGCGGGTCTTCGAGATCAACCGCAACTTCCGCAACGAGGGATTGTCGACCCGTCA
CAATCCCGAGTTCACGATGCTCGAGTTCTACTGGGCCTACGCCGATTACCGTGACCTGCTGGATCTCACCGAAGCGATGA
TTCGCGACGTCGCGCACGAGGTGCTGGGCACGACCACGGTCGAGTATCAGGGGGCACGCTACGAACTCGGCGAGCCGTTC
CAGCGGCTCACGCTGCGGCAGTCGATCCTCGAGTACGGCGACGGTCTCGGCGAAAGCGACATCGACACGTTCGATGGCGC
GCGTGCCACCTGCGAGCGTCTGGGCATTCCCGTCAAGCCGAGCTGGGGGCTGGGCAAGTTGCAGACCGAGATCTTCGAGG
CCGTCGCCGAAGACAAGCTCGACCGCCCGACGTTCATTACCGAATACCCGGCCGAGGTCAGTCCGCTGGCGCGGCGCAAC
GATACCAATCCCCATGTGACCGATCGCTTCGAGTTCTTCGTCGGCGGCCGCGAGCTCGCCAATGGCTTCTCGGAGCTCAA
CGACGCCGAGGACCAGGCCGAACGCTTCGCCGCCCAGGCGGCGGAGAAGGATGCCGGCGACCTCGAGGCGATGTACTACG
ATGCCGACTACGTACGCGCGCTGGAGTACGGCATGCCGCCGACCGCGGGTGAGGGGATCGGCATCGACCGGCTGGTCATG
CTGCTCACCGATAGCCCGTCGATCCGGGATGTGTTGTTGTTCCCGGCGATGCGTCCCTCGGCCGACTGA

Protein sequence :
MANQDAAQHDENHLIAERRAKLAARRDQAAEAGGSAFPNDFRRDSLAAELQAELGDKDKAELETLDRRASVAGRIMRKRG
PFIVIQDVSDQIQLYVDKKGLPAETLDDIKSWDIGDIVAARGPVHKSGKGDLYVMMGEAQLLTKSLRPLPDKYHGLTDTE
ARYRQRYVDLIMNPESRRVFEVRSRVISGIRRFLVERGFMEVETPMLQQIPGGATARPFVTHHNALDIDMYLRVAPELYL
KRLVVGGFERVFEINRNFRNEGLSTRHNPEFTMLEFYWAYADYRDLLDLTEAMIRDVAHEVLGTTTVEYQGARYELGEPF
QRLTLRQSILEYGDGLGESDIDTFDGARATCERLGIPVKPSWGLGKLQTEIFEAVAEDKLDRPTFITEYPAEVSPLARRN
DTNPHVTDRFEFFVGGRELANGFSELNDAEDQAERFAAQAAEKDAGDLEAMYYDADYVRALEYGMPPTAGEGIGIDRLVM
LLTDSPSIRDVLLFPAMRPSAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-139 60
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 1e-80 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_575041.1 lysyl-tRNA synthetase VFG1668 Protein 2e-139 60