Gene Information

Name : thyA (RPD_3354)
Accession : YP_570479.1
Strain : Rhodopseudomonas palustris BisB5
Genome accession: NC_007958
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3717872 - 3718666 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGATCCAGTACCACGACTTGCTTGAGCGAATCCTCAGCGACGGAACTGAAAAACACGACCGCACCGGGACCGGTACGCT
GTCGGTGTTCGGCCATCAGATGCGGTTCAATCTGGCCGCCGGATTCCCGATGCTGACAACCAAACGGTTGCCGCTCAAGG
CGATCGTCCACGAACTGCTGTGGTTTCTGCAGGGCGACACCAACATCAAATACCTGCGCGACAACGGCGTGACGATCTGG
GACGAGTGGGCCGACGCCAATGGCGATCTCGGCCCGGTCTATGGCGCGCAATGGCGCTCCTGGCCGGCCGCGGACGGTCG
CAGCATCGACCAGATCGCCAATATCGTCGAGATGATCAAGCGCAACCCGGACTCGCGGCGGCTGATCGTGACGGCGTGGA
ATCCGGCCGATGTCGATCGGATGGCGCTGCCGCCGTGCCATTGCCTGTTCCAGTTTTACGTCGCTGGCGGCAAGCTGTCT
TGCCAGTTGTATCAACGTTCCGCCGACGTGTTTCTCGGCGTGCCGTTCAACATCGCCTCCTATGCGCTGCTGACGATGAT
GATAGCGCAAGTCACCGGTCTGAAGCCGGGCGAATTCATCCACACCCTCGGCGACGCGCATTTGTATTCCAATCATCTGG
AGCAGGCTCGCCTGCAACTGACCCGCGCGCCACGCGCGCTGCCGGAGATGGTGATCGATCCCGCCGTGAAGGACGTGTTC
GGCTTCCGTTACGAGGACTTCACCCTGCAGGGCTACGATCCGCATCCGCACATCAAGGCCGAGGTCGCGGTGTGA

Protein sequence :
MIQYHDLLERILSDGTEKHDRTGTGTLSVFGHQMRFNLAAGFPMLTTKRLPLKAIVHELLWFLQGDTNIKYLRDNGVTIW
DEWADANGDLGPVYGAQWRSWPAADGRSIDQIANIVEMIKRNPDSRRLIVTAWNPADVDRMALPPCHCLFQFYVAGGKLS
CQLYQRSADVFLGVPFNIASYALLTMMIAQVTGLKPGEFIHTLGDAHLYSNHLEQARLQLTRAPRALPEMVIDPAVKDVF
GFRYEDFTLQGYDPHPHIKAEVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-84 65