Gene Information

Name : guaA (RPD_2269)
Accession : YP_569405.1
Strain : Rhodopseudomonas palustris BisB5
Genome accession: NC_007958
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2533666 - 2535336 bp
Length : 1671 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGTCGGCCGCTGCACCTGTTTTCCCGGTTGCGAGCCGGGCTGCGGTCGCGTATCTGCTGCCCATGACAGCCCCCAGCAC
ATCCTCCGCTTCCGCCGCCGATTCCTCGCCGCACGTCGCCGCGATCCACGAAAAAATCCTGATCGTCGATTTCGGCTCGC
AGGTCACGCAGTTGATCGCCCGCCGCGTCCGCGAGGAGGGGGTCTATTCCGAGATCGTGCCGTTCCAGAAGGCCGAAGCC
GCCTTCGCCGAGATGAAGCCGAAGGCCGTGATCCTGTCCGGCGGGCCGGCCTCGGTGCTGGAGGCCGACGCGCCCAAGGC
GCCGATGGCGATCCTTCAGGCCGGCGTCCCGGTTCTCGGCATCTGCTACGGCGAGCAGACCATGGCGGCGCAGCTCGGCG
GCACCGTCGAGGGCGGGCATCACCGCGAATTCGGCCGCGCCACGATCGAGATCACCGACGACTGCGCGCTGTTCGACGGC
GTCTGGCAGAAGGGCGGCCAGTACGACGTCTGGATGAGCCACGGCGACCGCGTCACCAAACTGCCCGAAGGCTTCCGCGG
CGTCGCCAAGGCGGCGGGCTCGCCGATCGCGGTGATCGCCGACGATTCGCGCAAGTTCTACGCGATGCAGTTTCATCCCG
AGGTGGTGCATACGCCGGACGGCGCGAAAATCCTGCGCAACTTCGTCCGCAAGGTGGCGGGCCTGACCGGCGACTGGACG
ATGCGCGCCTTCCGCGAGGAGGCGGTCGAGAAGATCCGCGCTCAGGTCGGGCAGGGCAAGGTGATCTGCGGCCTGTCCGG
CGGCGTCGACTCGGCAGTCGCTGCGGTGCTGATCCACGAGGCGATCGGCGATCAGCTCACCTGCGTGTTCGTCGATCACG
GGTTACTGCGCAAGGACGAGGGCAAGTCCGTCGTCGACCTGTTCCGCCACCACTACAACATCCCGCTGGTGCATGTGGAC
GCGGCTGATACGTTCCTCGGCGCGCTCAAAGGCGTCACCGACCCGGAGCAGAAGCGCAAGATCATCGGCAAATTGTTCAT
CGACGTGTTCGACGCCGAGGCCAAGGTGGTCGGCGGCGCGGATTTTCTGGCGCAGGGCACGCTGTATCCCGACGTGATCG
AGAGCGTGTCGTTCACCGGCGGGCCGTCGGTGACGATCAAGTCGCACCACAATGTCGGCGGTCTGCCCGAACGCATGAAC
ATGAAGCTGGTCGAACCCTTGCGCGAATTGTTCAAGGACGAGGTCCGCGCGCTCGGCCGCGAGCTCGGCCTGCCGGACGT
GTTCGTCGGCCGCCATCCGTTCCCGGGGCCCGGGCTGGCGATCCGCTGCCCCGGCGAGATCACCGCGGAAAAGCTGGAGA
TTCTGCGCAACGCCGACGCGGTCTATATCGATCAGATCCGCAAGGCCGGTCTGTATGACGTGATCTGGCAGGCGTTCGCG
GTGCTGCTGCCGGTCAAGACCGTCGGCGTGATGGGCGACGGCCGCACCTACGAATACGTCGTCGGGCTGCGCGCCGTGAC
CTCGACCGACGGCATGACCGCCGACTTCTACGCCTTCGACATGAACTTCCTCGGCGCCACCGCCACCCGCATCATCAACG
AGGTCAAGGGCGTCAACCGCGTAGTCTACGACATCACCTCGAAGCCGCCAGGGACGATCGAGTGGGAGTGA

Protein sequence :
MSAAAPVFPVASRAAVAYLLPMTAPSTSSASAADSSPHVAAIHEKILIVDFGSQVTQLIARRVREEGVYSEIVPFQKAEA
AFAEMKPKAVILSGGPASVLEADAPKAPMAILQAGVPVLGICYGEQTMAAQLGGTVEGGHHREFGRATIEITDDCALFDG
VWQKGGQYDVWMSHGDRVTKLPEGFRGVAKAAGSPIAVIADDSRKFYAMQFHPEVVHTPDGAKILRNFVRKVAGLTGDWT
MRAFREEAVEKIRAQVGQGKVICGLSGGVDSAVAAVLIHEAIGDQLTCVFVDHGLLRKDEGKSVVDLFRHHYNIPLVHVD
AADTFLGALKGVTDPEQKRKIIGKLFIDVFDAEAKVVGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMN
MKLVEPLRELFKDEVRALGRELGLPDVFVGRHPFPGPGLAIRCPGEITAEKLEILRNADAVYIDQIRKAGLYDVIWQAFA
VLLPVKTVGVMGDGRTYEYVVGLRAVTSTDGMTADFYAFDMNFLGATATRIINEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 8e-133 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-133 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-133 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-119 52