Gene Information

Name : leuS (Sden_0797)
Accession : YP_561810.1
Strain : Shewanella denitrificans OS217
Genome accession: NC_007954
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 914322 - 916940 bp
Length : 2619 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGGCGGCATGGCCGGAAATAGATTAATGCAAGAGCTATATAATCCCTCAGAAATTGAAGCCTTAGTGCAAAAGCACTG
GCAAGAACACAAAACATTTGAAGTCACTGAAGATGAAAGCAAAGAGAAGTTTTATTGTCTCTCTATGTTTCCTTATCCAT
CAGGTCGCCTTCACATGGGCCATGTCCGTAATTACACCATAGGCGATGTGGTTGCTCGTTACCAGCGTCTACAAGGTAAA
AATGTGTTGCAACCCATAGGTTGGGACTCATTTGGTCTGCCTGCAGAAAACGCAGCAATCAATAACAAGACCTCGCCAGC
CCCCTGGACTTACGAAAACATCGACTACATGAAGAACCAGCTTAAGCTGTTAGGCTTTGGTTATGATTGGAGCCGTGAAA
TCGCCACTTGTACTCCTGAATACTACCGTTGGGAGCAATGGTTCTTCACCAAGCTGTATGAAAAAGGCATGGTTTACAAG
AAGACCTCATCGGTAAACTGGTGTCCAAATGATGAAACTGTACTGGCCAACGAGCAAGTACAAGACGGCTGCTGCTGGCG
TTGTGACACCCCAGTAATCCAAAAAGAAATTCCGCAATGGTTCATTAAGATCACCGACTACGCCGAAGAATTGCTTAACG
ATATCGACACCTTAGACGGCTGGCCTGAGCAAGTTAAGGCCATGCAGCGTAACTGGATTGGTCGCAGCGAAGGCATAGAA
ATGACCTTTAAGGTCAAAGATAGCGAGCAAAGCTTCGACATCTACACCACGCGCCCCGATACTTTAATGGGCGTGACGTA
TGTGGCGATTGCTGCAGGTCACCCATTAGCCGAGCAAGCCGCTAGCACTAACCCTGCGTTAGCCGCCTTTATCGAAGAGT
GTAAAAATGCCGATACCACGGAAGCCGCCATGGCCTCTATGGAGAAAAAAGGCGTGGCCACGGGTCTTGAAGCTGTGCAC
CCTATTTCTGGCAAATTAGTGCCAATTTGGGTCGCAAACTTTGTGCTGATGAATTATGGCACTGGCGCTGTAATGTCAGT
CCCTGCGCACGATCAACGTGACTATGAATTTGCTAAGGCTTATGGCCTTGAAATGCAAGCCGTCATCAAGCCCGCTGATA
GCGAAGTGGACATAAGCAAAGAAGCTTACACAGAAAAAGGCGTGCTATTTAACTCAGGCACCGCTTTCCCTGAGCTTGAT
GGCCTTGAGTTCCAAGCCGCTTTCGATGCCATTGACGCCCGCTTAACCGCCGAAGGCAAAGGCAAACGTCAAGTGAATTA
TCGTCTACGTGACTGGGGCGTTTCTCGTCAACGTTACTGGGGCGCGCCCATTCCTATGGTGACCCTGGCCGATGGCACTG
TGATGCCCACTCCTGAAGATCAACTGCCAGTCATACTGCCAGAAGATGTCGTCATGGATGGCATTCAAAGCCCAATCAAG
GCCGATAAAGCCTGGGCCGAGACCACGGTTGACGGCAAGCCAGCGTTTCGTGAAACCGATACCTTCGACACCTTCATGGA
GTCATCTTGGTATTACGCCCGTTACTGTAGCCCCCATGCGGATGAGATGTTAGATCCCGCCAAGGCTAACTACTGGTTAC
CGGTAGATCAGTACATTGGCGGCATAGAACACGCTTGCATGCATTTGCTCTATTTCCGTTTCTTCCACAAGTTACTCCGT
GATGCGGGACTTGTGAACTCAAACGAGCCAGCCAAGCGTCTATTGACCCAAGGCATGGTGCTTGCGGATGCGTATTACTA
CACCAATGACAAAGGTGCCCGCGTATGGGTATCACCATTGGAAGCCGAAGTTGTTGAAAAAGACGATAAAGGCCGCGTAG
TCAAAGCGGTAGACAGCCAAGGCAATGAACTGGTTTATACAGGTATGAGCAAGATGTCTAAGTCGAAAAACAACGGCATA
GACCCGCAAACCATGGTGGAGAAATACGGCGCCGATACCGTGCGTCTATTTATGATGTTCGCATCACCGCCTGAGCTTAC
CCTCGAATGGCAAGAGTCTGGCGTTGAAGGCGCTCACAGATTCATTAAGCGTCTGTGGAAACTTGCCAGTGACCATGTTG
CCGCTGGTCCAACTGAAGCCTTGGATGTGAGCAAGTTAAGCTCATCGCAAAAAGCCCTGCGCCGTGAGCTGCATAAGACT
ATCGCTAAAGTCAGCGATGACATTGGCCGTCGTCAGATGTTCAACACCGCCGTTGCTGCTGTGATGGAGCTGATGAATCA
TTTATCAAAAGCACCGCAAGACAGCGCCCAAGACCGTGCTTTACTGGCTGAAGCCTTAAGCGCTGTGACCCGTTTGCTAT
ACCCTATCATCCCGCACATGAGCTTTACCCTGTGGCATGAACTAGGCAATAGCAACAACATCGAAGACAGCCGCTGGCCA
GACGTCGATGAAGCGGCGCTAGTGGAAGACAGCAAGCTGATTGTGGTGCAAGTGAACGGTAAAGTTCGCGCTAAAATCAC
AGTGGCTGCCGATGCGACGAAAGAAGCCGTTGAGCAGCTTGGCTTAGATGATGAACACGTGCAAAAACACCTTGAAGGCT
TAACGGTTCGCAAAGTGATTTATGTACCTGGCAAACTGCTTAGCCTAGTCGCTAACTAG

Protein sequence :
MGGMAGNRLMQELYNPSEIEALVQKHWQEHKTFEVTEDESKEKFYCLSMFPYPSGRLHMGHVRNYTIGDVVARYQRLQGK
NVLQPIGWDSFGLPAENAAINNKTSPAPWTYENIDYMKNQLKLLGFGYDWSREIATCTPEYYRWEQWFFTKLYEKGMVYK
KTSSVNWCPNDETVLANEQVQDGCCWRCDTPVIQKEIPQWFIKITDYAEELLNDIDTLDGWPEQVKAMQRNWIGRSEGIE
MTFKVKDSEQSFDIYTTRPDTLMGVTYVAIAAGHPLAEQAASTNPALAAFIEECKNADTTEAAMASMEKKGVATGLEAVH
PISGKLVPIWVANFVLMNYGTGAVMSVPAHDQRDYEFAKAYGLEMQAVIKPADSEVDISKEAYTEKGVLFNSGTAFPELD
GLEFQAAFDAIDARLTAEGKGKRQVNYRLRDWGVSRQRYWGAPIPMVTLADGTVMPTPEDQLPVILPEDVVMDGIQSPIK
ADKAWAETTVDGKPAFRETDTFDTFMESSWYYARYCSPHADEMLDPAKANYWLPVDQYIGGIEHACMHLLYFRFFHKLLR
DAGLVNSNEPAKRLLTQGMVLADAYYYTNDKGARVWVSPLEAEVVEKDDKGRVVKAVDSQGNELVYTGMSKMSKSKNNGI
DPQTMVEKYGADTVRLFMMFASPPELTLEWQESGVEGAHRFIKRLWKLASDHVAAGPTEALDVSKLSSSQKALRRELHKT
IAKVSDDIGRRQMFNTAVAAVMELMNHLSKAPQDSAQDRALLAEALSAVTRLLYPIIPHMSFTLWHELGNSNNIEDSRWP
DVDEAALVEDSKLIVVQVNGKVRAKITVAADATKEAVEQLGLDDEHVQKHLEGLTVRKVIYVPGKLLSLVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-162 42