Gene Information

Name : thyA (Sden_2779)
Accession : YP_563781.1
Strain : Shewanella denitrificans OS217
Genome accession: NC_007954
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3319716 - 3320510 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGCAATATCTAGCATTAATGGAGCACATACTGGCCCATGGCGCGGTGAAAACAGATAGAACCGGAACGGGCACTCG
TTCAGTCTTTGGCTATCAGATGCGCTTCGATTTAAATCAAGGGTTCCCCTTAGTTACCACTAAAAAGTGTCACCTACGTT
CTATCATACATGAGCTGCTATGGTTTCTGCAGGGCGACACCAATGTGGCGTATCTACATGAGCATAATGTGAGTATTTGG
GATGAATGGGCCGATGATAAAGGCAATTTGGGCCCAGTGTATGGCGCTCAGTGGCGCAGCTGGCCGACCCAATCCGGTAA
GGCGGTGGATCAAATCAGCCAGATCATAGAACAAATCAAGACTCAGCCAGATTCGAGACGCCTAATCGTCTCGGCATGGA
ATGTGGGCGAACTGGATAAAATGGCATTAGCGCCTTGTCATGCCTTGTTCCAGTTTTATGTCGCCGATGGCAAGTTGTCT
TGCCAGCTGTATCAACGAAGCTGTGATGTCTTCTTAGGACTGCCCTTTAATATTGCCAGTTATGCCTTGTTGACCATGAT
GGTCGCTCAACAGTGCGATCTCGCCTTGGGTGATTTTGTCTGGACTGGCGGTGATACCCACTTGTATTCCAATCATATGG
AACAGACTAAGCTGCAGCTAAGTCGCGAGCCTCATGCCCTGCCACAAATGAATATATTACGTAAGCCAGAATCGATTTTT
GATTATCAATTCGATGATTTTGAGTTGGTTAATTATCAGCCTCACCCACACATTAAAGCGCCTGTGGCCATCTAG

Protein sequence :
MKQYLALMEHILAHGAVKTDRTGTGTRSVFGYQMRFDLNQGFPLVTTKKCHLRSIIHELLWFLQGDTNVAYLHEHNVSIW
DEWADDKGNLGPVYGAQWRSWPTQSGKAVDQISQIIEQIKTQPDSRRLIVSAWNVGELDKMALAPCHALFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTKLQLSREPHALPQMNILRKPESIF
DYQFDDFELVNYQPHPHIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-83 63
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-59 46