Gene Information

Name : Sden_2666 (Sden_2666)
Accession : YP_563668.1
Strain : Shewanella denitrificans OS217
Genome accession: NC_007954
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3197407 - 3198129 bp
Length : 723 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGGAATGCGCAGTTGTTATCCCAGCTAGATATCAATCTAGCCGTTTCCCAGGGAAACCATTAGTTAATATCCTTGGGAA
ACCAATGATACAGCACGTTTGGGAGCGGTGTTCTGCTGCTGTTGGAGCAGAAAATGTTTATGTAGCAACAGATAATGATA
AGATTTATGAAGTATGTAATGCTTTTGGTGCAAAAGTTATTATGACTTCATCCGAATGCTTAACGGGTACAGATAGATTA
GCTGAGGCCAATCTGCAGTTGGATTGCGATTTTATCATTAATGTACAGGGCGATGAGCCTTTGATAGAACCTGATGATAT
TCGAACTGTTATAGCAAAATATAAAGAACAACCAAATACGGTTGTTAATGCGATGTGTGCAATTTATTCAGAAGATGAAT
TCAGATCCTTTACCGTACCAAAAGTTGTTGTAAGCAAAACTGGTAATTTACTCTATATGAGTCGCTCTCCTATACCAGTC
ACAAAAAACAATGAGTATACTTTTGGTTATAAGCAAGTTTGTATCTATGCTTTTTCTAAAGAGCATCTAGTCTTTTTTGC
TTCTCATAAAGAGAAAACAAAAATTGAGCAGGTTGAGGATATTGAAATATTACGTTTTATAGAGAATGATATTCCAGTAC
AGATGATAGAAGTGCCAAGTTCTAGTATTGCCGTTGATACTCCAGGAGATGTACAACGTGTAATAATGAGAATGCAAAAT
TAA

Protein sequence :
MECAVVIPARYQSSRFPGKPLVNILGKPMIQHVWERCSAAVGAENVYVATDNDKIYEVCNAFGAKVIMTSSECLTGTDRL
AEANLQLDCDFIINVQGDEPLIEPDDIRTVIAKYKEQPNTVVNAMCAIYSEDEFRSFTVPKVVVSKTGNLLYMSRSPIPV
TKNNEYTFGYKQVCIYAFSKEHLVFFASHKEKTKIEQVEDIEILRFIENDIPVQMIEVPSSSIAVDTPGDVQRVIMRMQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK15335.1 unknown Not tested Not named Protein 2e-53 52
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-38 43
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-38 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-38 42