Gene Information

Name : Sden_2134 (Sden_2134)
Accession : YP_563139.1
Strain : Shewanella denitrificans OS217
Genome accession: NC_007954
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2532280 - 2533017 bp
Length : 738 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAGTTACCCTGTTGATCCCGGCCCGTTTCGGCTCTAGTCGTTTTCCGGGCAAGCCGCTTGCCCCGATTAATGGAAA
GCCGATGATCCAGCACGTCTATGAGCGTGCATCCCTTGCCAAAGGGCTAGACGCTATTTATGTGGCAACCGATGATGATC
GCATTAAAGATGCCGTTGAGGCATTTGGTGGCAAAGTCGTCATGACTAGCGCCGCTGCCGCCTCAGGCACGGATCGGATC
AACGATGCCATAGAGCAGTTAGGCTTAAGCGACGACGATTTAGTCATTAACCTACAGGGCGACCAGCCTCTTATCGACCC
GATTTCTATCGAGCAAATTGTTAGCTTGTTTGAACGTCATCCGGGTGAATTCGAAATGGCTACCTTAGGCTTTGAAATCA
CAGACAAGAGTGAACTTGACGACCCCATGCACGTTAAAATGGTGTTCGATAATGACTTTAATGCCCTATATTTCTCCCGT
GCCCGCATTCCTTTTGGCCGTGACACCAATGACTATCCTGTTTACAAGCACTTAGGTGTATACGCCTATACCAAACGTTT
CGTGAATGCCTTCGCCAAGTTGCCATTAGGTAAGCTTGAAGATTTGGAAAAGCTTGAGCAACTGCGAGCCTTAGAATATG
GCCATAAGATCAAAGTGGCTATCAGCGCCTTCGATTCACCGGAAGTGGATACCCCAGAAGATATCCGCAAGTGTGAGCAG
CGTTTAGCCGTCGACTAA

Protein sequence :
MKVTLLIPARFGSSRFPGKPLAPINGKPMIQHVYERASLAKGLDAIYVATDDDRIKDAVEAFGGKVVMTSAAAASGTDRI
NDAIEQLGLSDDDLVINLQGDQPLIDPISIEQIVSLFERHPGEFEMATLGFEITDKSELDDPMHVKMVFDNDFNALYFSR
ARIPFGRDTNDYPVYKHLGVYAYTKRFVNAFAKLPLGKLEDLEKLEQLRALEYGHKIKVAISAFDSPEVDTPEDIRKCEQ
RLAVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 6e-41 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-41 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-41 44