Gene Information

Name : sirA; uvrY (Sden_1436)
Accession : YP_562445.1
Strain : Shewanella denitrificans OS217
Genome accession: NC_007954
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2197
EC number : -
Position : 1674341 - 1674985 bp
Length : 645 bp
Strand : +
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence : 
TTGATTTCTGTATATTTAGTCGACGACCATGAGCTGGTTAGAACCGGCATTAGGCGCATCTTAGAAGATGAGCGTGGTAT
TAAAGTCGTAGGCGAAGCCCCCGATGGTGAAACTGCGGTGCAGTGGTCGCGTCATAATGAAGCCGATGTCATCTTGATGG
ACATGAACATGCCCGGCATGGGGGGGTTAGAAGCTACAAGAAAAATCCTTCGTTATCAACCAGATGCGAAAATTATTGTG
CTGACCGTTCAAACTGAAGATCCTTTCCCAACCAAAGTGATGCAAGCCGGTGCCTCAGGCTATTTAACCAAAGGTTCGAC
CTCCCCAGAAGTATTGCGCGCCATTCAACAGGTCGCACGAGGCCAGCGCTATTTATCCCCAGAAATTGCCCAGCAGATGG
CTCTCAGCCAATTCAGTCACACGGACGATAACCCCTTTGTTAATCTGTCTGAGCGTGAATTGCAGATCATGATGATGATC
ACCAGCGGTGAGAAGGTGAACGATATTTCAGAGAAACTTAATCTGAGTCCGAAAACCGTCAACAGCTATCGCTATCGTCT
GTTTGCCAAACTGGGTATTGGTGGTGATGTTGAGCTTACCCGTTTAGCAATACGTTACAAGATGCTAGATACCGGCACTT
TTTAA

Protein sequence : 
MISVYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWSRHNEADVILMDMNMPGMGGLEATRKILRYQPDAKIIV
LTVQTEDPFPTKVMQAGASGYLTKGSTSPEVLRAIQQVARGQRYLSPEIAQQMALSQFSHTDDNPFVNLSERELQIMMMI
TSGEKVNDISEKLNLSPKTVNSYRYRLFAKLGIGGDVELTRLAIRYKMLDTGTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 4e-53 50
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 4e-53 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sirA; uvrY YP_562445.1 response regulator VFG1889 Protein 1e-51 51