Gene Information

Name : guaA (Sden_1270)
Accession : YP_562279.1
Strain : Shewanella denitrificans OS217
Genome accession: NC_007954
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1482739 - 1484316 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCAATATTCATGAGCATAAGATACTGATCTTAGATTTTGGATCGCAATATACCCAATTAATCGCCCGCCGTATTCG
TGAAATTGGCGTCTACTGTGAGCTTTGGGCTTGGGATGTGAGTGAAGCGCAAATTCGTGAATTTAATCCTCAAGGGATCA
TTCTTGCGGGCGGTCCTGAAAGCGTAACCGCAGAGAATTCACCGCGAGCACCAGAATATGTGTTTAATGCCGGTGTGCCT
GTGCTAGGTATTTGTTATGGCATGCAAACCATGTCTGAGCAACTTGGCGGCAAAGTGATCCAAGGTGTAGGCGAGGGCGA
GTTTGGTTATGCCCAGGTTGAGATGTTACTCGAATCTGCGCTATTTAAAGGCATAGAAGATGCCATAAGCCCTGCGGGCC
GACCCTTACTCGATGTGTGGATGAGCCACGGTGATAAGGTTTCAGCCATACCTGAAGGTTTTAAGGCTGTGGCTAAGACA
GATACCTGTCCGTTTGCTGCTATGGCTAATGAAGAAAAGCGCTTCTATGGGGTGCAGTTCCACCCTGAGGTGACTCACAC
TCGCCAAGGTCTGCGTATGCTTGAACATTTTGCTGTGGCCATCTGTGGTTGCGGTACTAATTGGAAGCCAAGTTCAATCA
TAGAAGATGCCATCGAGCGCATTAAAGCCCAAGTGGGTGATGACGAAGTGATCTTAGGTTTGTCTGGCGGCGTGGACTCT
TCTGTCGTGGCCATGCTATTGCACCGCGCCATTGGCAAAAAACTCACCTGTGTGTTCGTTGATAACGGGTTACTGCGCTT
GAACGAAGCCGAGCAAGTGCTAGAAATGTTTGGCGATCATTTCGGGCTCAACATTGTCCACGTGGATGCGGAAAATCGCT
TCCTCGATGCCATGGCCGGTGTTGCCGATCCTGAAGCTAAGCGTAAAATCATTGGCCGAGTATTTGTGGAAATCTTCGAC
GAAGAATCCAAGAAATGCGCTAACGCTAAATGGCTGGCACAAGGCACTATTTATCCAGACGTGATTGAATCTGCGGGCAG
CGCGACTGGCAAAGCTCATGTGATTAAATCCCACCACAATGTGGGCGGCTTACCCGATGACATGGAAATGGGTTTAGTTG
AGCCACTGCGTGAGCTGTTTAAAGATGAAGTGCGTAAAATAGGTCTAGAGCTAGGCTTGCCATACAATATGCTTTACCGC
CACCCATTCCCAGGTCCTGGCCTTGGTGTTCGGGTATTAGGTGAAGTAAAGAAAGAGTATTGTGACTTACTGCGCCGCGC
CGATGCAATTTTCATCGAAGAGCTGCATAAAGCTGATTTATATAATAAAGTCAGCCAAGCCTTCACGGTATTCTTACCGG
TACGTTCTGTTGGTGTTATGGGTGATGGCCGTAAGTACGATTGGGTGGTGTCACTTCGTGCAGTAGAAACCATAGACTTT
ATGACAGCGCATTGGGCGCATTTGCCTTATGACTTCTTAGGCCGAGTGTCTAATCGTATCATTAACGAAGTCGATGGTAT
TTCCCGGGTAGTGTATGATATCTCCGGTAAGCCACCTGCGACTATCGAGTGGGAATAA

Protein sequence :
MSNIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVSEAQIREFNPQGIILAGGPESVTAENSPRAPEYVFNAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQVEMLLESALFKGIEDAISPAGRPLLDVWMSHGDKVSAIPEGFKAVAKT
DTCPFAAMANEEKRFYGVQFHPEVTHTRQGLRMLEHFAVAICGCGTNWKPSSIIEDAIERIKAQVGDDEVILGLSGGVDS
SVVAMLLHRAIGKKLTCVFVDNGLLRLNEAEQVLEMFGDHFGLNIVHVDAENRFLDAMAGVADPEAKRKIIGRVFVEIFD
EESKKCANAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-125 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-125 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-125 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-111 47