Gene Information

Name : guaA (Bxe_A1708)
Accession : YP_559299.1
Strain :
Genome accession: NC_007951
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 3018699 - 3020282 bp
Length : 1584 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACGACAAGATTCTGATCCTCGACTTCGGTTCGCAAGTCACCCAACTGATTGCACGTCGCGTTCGCGAAGCCAACGT
GTATTCGGAAATTCATCCGTACGACGTCGATGCGTCGTTCATTCGCGACTTCGCGCCGAAGGGCGTGATCCTTTCCGGCG
GCCCGAGCTCGGTCACTGAAACGGACACGCCGCGCGTGCCGCAGGCCGTGTTCGAACTCGGCGTGCCGGTGCTCGGCATC
TGCTACGGCATGCAGGCGATGGCCGAGCAGCTGGGCGGCAAGGTCGATATCGGCCACCTGCGCGAGTTCGGTTATGCCGA
GGTGCGCGCGCGCAACCACACGAGCCTGCTCGAAGGCATCAGCGACTTCACCACGCCGGAAGGCCACGGCATGTTGAAGG
TGTGGATGAGCCACGGCGACAAGGTGCTGGAAATGCCGCCGGGCTTCGCGCTGATGGCGTCGACGGAATCGTGCCCGATC
GCCGCGATGGCCGACGAAACGCGCCATTTCTACGGCCTGCAATGGCACCCGGAAGTCACGCACACCGTGCAGGGCCGCGC
CATGCTCGAACGCTTCGTGCTGAAGATCTGCGGCGCGCAGCCGGATTGGGAAATGGGCCACTATATCGACGAAGCCGTCG
CGAAGATCCGCGAGCAGGTCGGTCAGGAACATGTGATCCTGGGACTCTCGGGCGGCGTGGATTCGTCGGTGGCGGCGGCG
CTGCTGCATCGCGCGATTGGCGATCAGCTGACCTGCGTGTTCGTCGATCATGGCCTGTTGCGCCTGAACGAAGCCGAGCA
GGTAATGGCGACCTTCGCGGATCACCTGGGCGTGAAGGTGATTCACGTCGACGCGAGCGAGGTGTTCCTGCGCAAGCTGG
CCGGTGTGACCGATCCGGAAGCGAAGCGCAAGATCATCGGCGCGGAATTCGTCGAGGTGTTCCAGACCGAAGCCGGCAAG
CTGACCGATGCGAAGTGGCTGGCGCAAGGCACGATCTATCCGGACGTGATCGAATCGGCCGGCAAGGGCAAGAAAGCCAC
GCAGACGATCAAGAGCCATCACAACGTGGGCGGCCTGCCAGAGACGCTGAACCTGAAGCTGCTCGAGCCGCTGCGCGAAC
TGTTCAAGGACGAAGTGCGCGAACTCGGCGTCAAGCTCGGTTTGCCGCCGGCCATGGTGTACCGCCATCCGTTCCCGGGC
CCGGGTCTGGGCGTGCGGATTCTCGGCGAAGTGAAGCGCGATTTCGCGGACCTGCTGCGCCGCGCGGACGCGATTTTCAT
CGAGACGTTGCGGACTTTCATCGACAAGGAAACCGGCAAGTCCTGGTACGATCTGACGAGCCAGGCGTTCGCGGTGTTTC
TGCCGGTGAAGAGCGTGGGCGTGATGGGTGACGGGCGGACTTATGAGTATGTTGTCGCGCTGCGCGCCGTGCAGACGCTG
GACTTCATGACCGCGCATTGGGCGCATCTGCCGCATGAGTTGCTGGGGCATGTGTCGAACCGGATTATTAATGAAGTGCG
CGGGATTAACCGGGTGGTGTATGACATTTCGGGGAAGCCGCCGGCGACAATCGAGTGGGAATGA

Protein sequence :
MHDKILILDFGSQVTQLIARRVREANVYSEIHPYDVDASFIRDFAPKGVILSGGPSSVTETDTPRVPQAVFELGVPVLGI
CYGMQAMAEQLGGKVDIGHLREFGYAEVRARNHTSLLEGISDFTTPEGHGMLKVWMSHGDKVLEMPPGFALMASTESCPI
AAMADETRHFYGLQWHPEVTHTVQGRAMLERFVLKICGAQPDWEMGHYIDEAVAKIREQVGQEHVILGLSGGVDSSVAAA
LLHRAIGDQLTCVFVDHGLLRLNEAEQVMATFADHLGVKVIHVDASEVFLRKLAGVTDPEAKRKIIGAEFVEVFQTEAGK
LTDAKWLAQGTIYPDVIESAGKGKKATQTIKSHHNVGGLPETLNLKLLEPLRELFKDEVRELGVKLGLPPAMVYRHPFPG
PGLGVRILGEVKRDFADLLRRADAIFIETLRTFIDKETGKSWYDLTSQAFAVFLPVKSVGVMGDGRTYEYVVALRAVQTL
DFMTAHWAHLPHELLGHVSNRIINEVRGINRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-120 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 9e-121 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-121 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-105 50