Gene Information

Name : Mfla_0399 (Mfla_0399)
Accession : YP_544511.1
Strain : Methylobacillus flagellatus KT
Genome accession: NC_007947
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 408272 - 409273 bp
Length : 1002 bp
Strand : -
Note : -

DNA sequence : 
ATGCGCATCGTCTTTTTCAGCACCCAGGTATATGACCGGGAAAGTTTTCTGGCCCTCCCCAGGCTCCAGAATGCCGAGTT
CATTTTCCAACAGCCCAAACTCACGTTGGATACTGCCGTGCTTGCCACAGGCGCGGAAGTCGTCTGTGCCTTCATCAATG
ACGACCTGTCCGCGCCTGTGCTGGAGAGACTGGCAGCCAACGGTACCAAGCTGATTGCACTGCGCTCCGCAGGCTACAAC
CATATCGACCTGGAGGCTGCGCAAAGACTCAACCTGGCAGTGGTGCGCGTGCCCGCCTATTCGCCCCATGCCATTGCGGA
ACATACCGTCGCATTGATCCTGGCCCTCAATAGACACCTGACGCGCGCCTACAACCGTACCCGCGAGGGTGATTTCAGCC
TGCGCGGCTTGACAGGGTTCGACCTAGTCCACAAGACAGTAGGCATCATCGGCACCGGACAGATCGGTGCAGCTTTTGCC
CGCATCATGGCAGGTTTCGGCTGCAGGATACTGGCTTACGATCCCTACCCCAACCCGGAAGTCATTGCGCTCGGCGCCAG
CTACCTCGAACTCGATACGCTGTTGGCGCAATCCCACATCGTCAGCCTGCATTGCCCGTTGAGCCCTGCCACCCACCATC
TCATCAATGCCGGTTCGCTCAGCCGCATGCAGCCAGGCAGCATGCTCATCAACACCAGCCGCGGCGCACTCGTGGATACG
CCGGCCGTGATCGAAGCGCTGAAGAGCGGACACCTCGGCTATCTTGGGCTGGACGTCTATGAAGAAGAAGCAGACCTGTT
TTTCGAGGACCTATCCGACTTTCCGTTGCAGGATGACGTACTGGCGCGGCTGCTGACCTTTCCCAACGTCATCATCACTG
CCCACCAGGCGTTTCTCACACGCGAAGCGCTCAATGCCATTGCCAGCACCACGTTAGACAATATCAGCGCCTGGGCAGCA
GGCCACCCTCAGAACCTGGTCAGGCTGGAAACAGGAAGCTGA

Protein sequence : 
MRIVFFSTQVYDRESFLALPRLQNAEFIFQQPKLTLDTAVLATGAEVVCAFINDDLSAPVLERLAANGTKLIALRSAGYN
HIDLEAAQRLNLAVVRVPAYSPHAIAEHTVALILALNRHLTRAYNRTREGDFSLRGLTGFDLVHKTVGIIGTGQIGAAFA
RIMAGFGCRILAYDPYPNPEVIALGASYLELDTLLAQSHIVSLHCPLSPATHHLINAGSLSRMQPGSMLINTSRGALVDT
PAVIEALKSGHLGYLGLDVYEEEADLFFEDLSDFPLQDDVLARLLTFPNVIITAHQAFLTREALNAIASTTLDNISAWAA
GHPQNLVRLETGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 1e-41 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mfla_0399 YP_544511.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding NC_014475.1.orf2.gen Protein 1e-40 42
Mfla_0399 YP_544511.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding NC_005054.2598279.p0 Protein 1e-40 42
Mfla_0399 YP_544511.1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding AF310956.2.orf4.gene Protein 6e-42 41