Gene Information

Name : hemC (Mfla_0035)
Accession : YP_544147.1
Strain : Methylobacillus flagellatus KT
Genome accession: NC_007947
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 34442 - 35374 bp
Length : 933 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAACGCTCCCAAGACACTGGTGATCGCCTCGCGCGAAAGCGCATTGGCCATGTGGCAGGCCCAATACATCCAGGGCCG
TTTGCAAACCTTGTATCCGGAAACCGAGGTCACCATCCTCGGCATGACAACCACAGGCGACCAGATCCTGGATTCACCCC
TGGCCCGTATCGGCGGCAAGGGCTTGTTCGTCAAGGAGCTGGAGCAAGCACTGGCGGACGGCCGTGCCGACCTCGCCGTG
CATTCCATGAAGGACGTGCCCATGCATTTGCCGCCCGGCTTTGCCCTGGCCGCGATCAGCGAGCGCGATGACCCGCGCGA
TGCGTTCGTTTCCAATGATTACCCCAACCTGGCCTCCCTGCCTGCAGGCAGCATTGTCGGCACCTCCAGCCTGCGCCGCC
AGAGCCAATTGCAGGCACGGTTTCCCGGCCTCAAGGTGGAATCGCTGCGCGGCAACCTGCAGACCCGCTTGCGCAAACTG
GACGAAGGTCAGTACGCCGCCATCATCCTCGCCGCTGCCGGCCTGAAGCGCCTGGGACTGGCATCTCGCATCCGGGAATC
GATTGATCCCGACAACAGCATCCCCGCCGTCGGGCAGGGCGCACTGGGTATCGAGATCAACGCTGAACGCCTTGACCTGC
TGAAGGTGCTGGCGCCGCTCAATCATCCCGAAACTGCAGCCTGCGTGGAAGCAGAACGCGGCATGAGCCGCGCCCTGGCA
GGAAGCTGCCAGGTACCGTTGGGCGCTTTTGCCCAGCAACATGGCGATACGCTCCAGATGACCGGTTTTGTTGCGAGCAT
TGACGGCAAGGAATTTTTGCGCGAATCGGTCCAAGGCCCTGCTGAGCAACCGGAAGCTTTGGGCCAGGCACTGGCTGCCA
AACTGGTGGCACTGGGGGCGGACCGCATTCTTGCTGCGCTCCCGCATGAGTGA

Protein sequence :
MNAPKTLVIASRESALAMWQAQYIQGRLQTLYPETEVTILGMTTTGDQILDSPLARIGGKGLFVKELEQALADGRADLAV
HSMKDVPMHLPPGFALAAISERDDPRDAFVSNDYPNLASLPAGSIVGTSSLRRQSQLQARFPGLKVESLRGNLQTRLRKL
DEGQYAAIILAAAGLKRLGLASRIRESIDPDNSIPAVGQGALGIEINAERLDLLKVLAPLNHPETAACVEAERGMSRALA
GSCQVPLGAFAQQHGDTLQMTGFVASIDGKEFLRESVQGPAEQPEALGQALAAKLVALGADRILAALPHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-71 57
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-71 57