Gene Information

Name : Mfla_2530 (Mfla_2530)
Accession : YP_546636.1
Strain : Methylobacillus flagellatus KT
Genome accession: NC_007947
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2712577 - 2714463 bp
Length : 1887 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCACCGACAAAAACCTGCAGCAGAATTTCCTCAATGCCACCGCCCAGGTCGATCCGGGCGCAACGCAGCCTTT
TACCAATTCCCGCAAGATCTATATCGAAGGCTCGCGCCCCGACATCCGCGTTCCTTTCCGCGAGATCAGCCTGTCCGATA
CGCCATCGGCATTCGGCGCCGAGAAGAACCCGCCGGTGATTGTCTACGACACTTCCGGTCCTTACACTGACCCGGATGTG
CAGATCGACATCCGCAACGGTTTGCCGGCCCTGCGCGCTGGCTGGATTGCCGAGCGCGGCGATACCGAGCAACTGGACGG
GCCGACTTCCAGCTATGGCCTGGAACGGCTGCACGATCCCAAGCTGGCCGACATGCGCTTCAACCTGCATCGCAAACCGT
TGCGTGCCAAGGCAGGCAGGAACGTGACGCAGATGCACTATGCGCGCCAAGGCATCATTACTCCGGAGATGGAGTTCATC
GCCATCCGCGAGAACCAGCGCCGCGAAGGCATGAGCGAACTGTTGCAGACCCAGCATGCCGGGCAGCATTTCGGCGCTTC
CATTCCTGAAATCATCACGCCTGAGTTCGTCCGGGACGAAGTGGCGCGCGGCCGGGCAATCATTCCTGCCAATATCAACC
ACCCCGAAATCGAGCCGATGATCATCGGCCGCAATTTCCTCGTGAAGATCAATGCCAATATCGGCAATTCCGCCGTCAGC
TCAAGCATAGGCGAAGAAGTCGAGAAGATGGTCTGGGGCACCCGCTGGGGCGGCGATACCGTGATGGACCTGTCCACCGG
CAAGAACATCCACGAAACGCGCGAGTGGATCATCCGCAATTCACCCGTGCCGATCGGCACCGTGCCTATCTACCAGGCGC
TGGAAAAGGTCAACGGCAAGGCCGAAGACCTGACTTGGGAAATCTTTCGCGATACCTTGATCGAGCAGGCGGAGCAGGGC
GTGGATTATTTCACCATCCATGCCGGCGTGCGTTTGCAGTACATTCCGATGACCGCCAGGCGCATGACCGGCATCGTCTC
GCGCGGCGGCTCCATCATGGCGAAGTGGTGCCTGGCGCACCATAAGGAGTCTTTCCTCTACGAGCATTTCGAGGAAATTT
GCGACATCATGAAGGCCTACGATGTCAGCTTCTCGCTCGGCGACGGCCTGCGTCCCGGCTCGATCTACGATGCCAATGAT
GAAGCCCAGTTTGCTGAGCTGAGAACCTTGGGTGAATTGACCCGGATCGCCTGGAAGCATGACGTGCAGACCATGATCGA
AGGCCCTGGCCACGTACCCATGCACATGATCAAGGAAAACATGGACTTACAGCTGGAGCATTGCGGCGAGGCCCCGTTCT
ATACTCTGGGACCTTTGACCACCGATATCGCACCCGGCTACGACCACATCACCTCCGGCATCGGCGCCGCGATGATAGGC
TGGTACGGTTGCGCGATGCTGTGCTACGTCACGCCGAAGGAGCACCTGGGCCTGCCGGATAAGGAAGACGTGCGCGTCGG
CATCGTCACCTACAAGATTGCCGCGCACGCCGCCGACCTGGCCAAAGGCCACCCCGGCGCTCAGATTCGCGACAACGCCC
TGTCCAAGGCACGTTTCGAGTTCCGGTGGGAGGACCAGTTCAACCTCGGCCTCGATCCGGAGAAAGCCAAGGAATTCCAC
GACGAGACCCTGCCGCAGGAAGGGGCCAAGCAGGCGCACTTCTGCTCCATGTGCGGTCCGCACTTTTGTTCAATGAAAAT
TACCCAGGACGTGCGCGAATATGCCAACAAGCTGGGTGTGGACGAGCAGGCGGCGCTGAGCAAGGGCATGCAGGAAAAGG
CGATCGAGTTCGTTAAGCGCGGCAGCGAGGTTTATCAGAAGGTTTAA

Protein sequence :
MNATDKNLQQNFLNATAQVDPGATQPFTNSRKIYIEGSRPDIRVPFREISLSDTPSAFGAEKNPPVIVYDTSGPYTDPDV
QIDIRNGLPALRAGWIAERGDTEQLDGPTSSYGLERLHDPKLADMRFNLHRKPLRAKAGRNVTQMHYARQGIITPEMEFI
AIRENQRREGMSELLQTQHAGQHFGASIPEIITPEFVRDEVARGRAIIPANINHPEIEPMIIGRNFLVKINANIGNSAVS
SSIGEEVEKMVWGTRWGGDTVMDLSTGKNIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQG
VDYFTIHAGVRLQYIPMTARRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICDIMKAYDVSFSLGDGLRPGSIYDAND
EAQFAELRTLGELTRIAWKHDVQTMIEGPGHVPMHMIKENMDLQLEHCGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIG
WYGCAMLCYVTPKEHLGLPDKEDVRVGIVTYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPEKAKEFH
DETLPQEGAKQAHFCSMCGPHFCSMKITQDVREYANKLGVDEQAALSKGMQEKAIEFVKRGSEVYQKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 76
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 76
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 75