Gene Information

Name : Mfla_2477 (Mfla_2477)
Accession : YP_546583.1
Strain : Methylobacillus flagellatus KT
Genome accession: NC_007947
Putative virulence/resistance : Resistance
Product : Beta-lactamase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : 3.5.2.6
Position : 2656370 - 2657152 bp
Length : 783 bp
Strand : -
Note : -

DNA sequence :
ATGAAATATGTACTGGCTATCGTTGTTGCCTTGCTTGTTTTCCCGGTTGAGGCCGCCGACTGGAAGGAGCGTGGCGATAT
TGGCGCACTTTTCAAAAGTGCGGGCATCAACGGAACATTTGTTCTTTATGATATTGCCGATGATGCATATATTGGCTACA
ACCAATCCAGGGCTGAGACGAGGTTTGTCCCGGCTTCAACCTTCAAGATTCCAAATACGCTGATTGGGCTCTCGGTTGGC
GCGGTTAAGGATGTGGATGAAGTCCTGCCTTACGGCGGCCAGCCACAGTTTATGAAAGAGTGGGAAGAGGATATGGGCTT
GAGAAAAGCCATTGCCCTGTCCAATGTTCCGATTTATCAACATCTCGCGCAGCGTATTGGGCTGGAGCACATGCGGGAAA
ACATCATGAAAATGGATTACGGGAACAAGGAGATTGGTTCCCAGGTGGATCGTTTCTGGCTCGATGGCCCGCTCAAGGTC
AGCGCGATAGAGCAGGCTCGGTTCCTTGCCAGGTTGGCTCAGGGCATATTGCCGTTCCCCGCAGCGTTGCAGGCAAGCGT
CAGGGAAATTGTCCAGGTGGATCAGGGTAAGGACTGGGTGCTATATGGCAAAACCGGTTGGGAGAGTGCCCCTAATCCCG
GAGTCGGATGGTGGGTGGGATGGGTGCATAAAAACAATCGTATTTACACATTCGCCTTGAATATGGATGTTCATAGCGCC
GTTGATGCAGACAAGCGAGTGGTGCTTGGCAGGAAAAGCCTTGCACTGTTGGGAGTATTGTAA

Protein sequence :
MKYVLAIVVALLVFPVEAADWKERGDIGALFKSAGINGTFVLYDIADDAYIGYNQSRAETRFVPASTFKIPNTLIGLSVG
AVKDVDEVLPYGGQPQFMKEWEEDMGLRKAIALSNVPIYQHLAQRIGLEHMRENIMKMDYGNKEIGSQVDRFWLDGPLKV
SAIEQARFLARLAQGILPFPAALQASVREIVQVDQGKDWVLYGKTGWESAPNPGVGWWVGWVHKNNRIYTFALNMDVHSA
VDADKRVVLGRKSLALLGVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
blaOXA-129 AET25386.1 OXA-129 beta-lactamase Not tested PAGI-2(C) Protein 7e-45 41
bla OXA-129 AFG30109.1 OXA-129 beta-lactamase Not tested PAGI-2 Protein 7e-45 41
oxa23 AEZ06035.1 OXA-23 class D beta-lactamase Not tested Tn6167 Protein 3e-41 41
BJAB0715_00989 YP_008216137.1 Beta-lactamase class D Not tested AbaR27 Protein 9e-42 41
oxa23 AEO37447.1 class D beta-lactamase OXA-23 Not tested AbaR4 Protein 9e-42 41
oxa-23 AFV47968.1 class D beta-lactamase OXA-23 Not tested AbaR25 Protein 7e-42 41
oxa-23 AFV47996.1 class D beta-lactamase OXA-23 Not tested delta-AbaR25 Protein 7e-42 41
bla(Oxa-23) AFH57213.1 carbapenemase Not tested AbaR4b Protein 7e-42 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mfla_2477 YP_546583.1 Beta-lactamase AY306130.1.gene1.p01 Protein 3e-72 58
Mfla_2477 YP_546583.1 Beta-lactamase JF273470.1.gene1.p01 Protein 1e-53 50
Mfla_2477 YP_546583.1 Beta-lactamase EU086830.1.gene1.p01 Protein 2e-52 49
Mfla_2477 YP_546583.1 Beta-lactamase AY619003.1.gene1.p01 Protein 2e-47 47
Mfla_2477 YP_546583.1 Beta-lactamase EU086834.1.gene1.p01 Protein 1e-52 45
Mfla_2477 YP_546583.1 Beta-lactamase AY587956.gene.p01 Protein 1e-31 42
Mfla_2477 YP_546583.1 Beta-lactamase AM932669.1.gene2.p01 Protein 4e-45 41
Mfla_2477 YP_546583.1 Beta-lactamase AY288523.1.gene1.p01 Protein 7e-41 41
Mfla_2477 YP_546583.1 Beta-lactamase FJ194494.1.gene1.p01 Protein 3e-41 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488987.1.gene1.p1 Protein 3e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase AY762325.1.gene1.p01 Protein 6e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488992.1.gene1.p1 Protein 2e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488989.1.gene1.p1 Protein 5e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase NC_011586.7044972.p0 Protein 4e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase JN638887.1.gene1.p01 Protein 1e-41 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488986.1.gene1.p1 Protein 3e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488991.1.gene1.p1 Protein 7e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488988.1.gene1.p1 Protein 3e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase HM488990.1.gene1.p1 Protein 5e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase AY795964.gene.p01 Protein 4e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase AF201828.gene.p01 Protein 8e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase NC_010481.6155789.p0 Protein 2e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase AY665723.gene.p01 Protein 2e-42 41
Mfla_2477 YP_546583.1 Beta-lactamase GU831575.1.gene1.p01 Protein 8e-43 41
Mfla_2477 YP_546583.1 Beta-lactamase EF102240.1.gene13.p0 Protein 4e-42 41