Gene Information

Name : Mfla_2244 (Mfla_2244)
Accession : YP_546352.1
Strain : Methylobacillus flagellatus KT
Genome accession: NC_007947
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2392924 - 2394366 bp
Length : 1443 bp
Strand : -
Note : -

DNA sequence :
ATGGCATTACGTAAAACAAAAATTGTGGCGACGCTGGGGCCGGCTTCCAGTGAGGAGGCGGTGATTGAGCGGCTGGTGGA
TGCCGGGATGGATGTAGTGCGACTCAATTTTTCGCATGGGTCTGCGCAAGACCATATTGCCCGCGCCGAGTTGGTGCGCG
ATATCTCCCGTCGCAGCGGGCGGCCAGTGGGGGTATTGTGCGACCTGCAGGGGCCGAAGATTCGTATCGGCAAGTTCGAA
AATGACCGCATCCTACTGAAGGCCGGCGACAGGTTCATCCTCGACGCGGCGTGCAAGTTGGGCAACCAGGAGCGGGTGGG
GTTGGATTACAAGACGCTGCCATCCGAAGTGGAGCCTGGTGCGGTGTTGCTGCTGGATGACGGGCGCATTGTGCTCAATG
TCGAAGCGGTGAACGGCGGCGAGGTGCATTGCACGGTGGCGGCCGGTGGAGTGCTGTCGAACAATAAGGGCATCAATCGT
AAAGGGGGAGGGCTTTCTGCGCCAGCGTTGACGCTGAAGGATCAGGAAGATATCCGGACGGCAGTGGCATTGGAGGCAGA
CTATATCGCTGTTTCGTTCCCGCGCAGCGGTGCGGATATCGAGCTGGCGCGCCACTTGGTCAGGGAGGCAGGCGGCCATG
CGGCGATTGTCGCCAAGATCGAGCGCGCGGAGGCGATAGATGCGCTCGAAGAGATTATCGATGCTGCTGATGTGATCATG
GTGGCGCGCGGCGACCTCGGCGTCGAGGTGGGCGATGCGGCGGTGCCCGGCTTGCAGAAGCGCATGATCCGCACGGCGCG
CATGCGCAACAAGCTGGTGATTACGGCGACGCAGATGCTGGAGTCCATGATCAGCAGCCCGATCCCGACCCGGGCAGAGG
TATCCGATGTCGCGAATGCCGTGCTGGATGGCACCGATGCGGTGATGCTTTCCGGCGAGACGGCTGTGGGGCATTATCCG
GTCGAGTCCATCCAGGCCATGCACCGTGTCTGTCTGGAGGCGGAGAAGGAGTATGATAGCCATCATCTTCAGGCGCCGAT
CAATGATGAATTCGAGTTCATCGATGAGGCGATTGCCATGGCATCGGTGTATGCGGCAGAACATTTGAATGTGAAGGCGA
TTGCTGCCCTGACAAAGTCGGGTTCATCTGTCACCTGGCTGTCACGCTCGAATACGAATGTGCCGATTTATGCCTTGACG
ACAGAACGCGACACAAGACGCAAGCTGACGTTGTACCGGGGGGTCTATCCTTATCATGTGGAGTTTGCTAGCCAGGAACT
GAGCAAGATACTCTACGATGCAGAGGAAACGCTATTGCGGCTGGGCGCTGTGCAGCGCGGCGATCTCATGATGCTGACCT
TCGGCGAGCCGATCGGCAAGGCGGGCGGCACCAATACCCTGCAGATCGTCAGAGTAGGCGAGCACAGGCGCGAGCGGCAC
TGA

Protein sequence :
MALRKTKIVATLGPASSEEAVIERLVDAGMDVVRLNFSHGSAQDHIARAELVRDISRRSGRPVGVLCDLQGPKIRIGKFE
NDRILLKAGDRFILDAACKLGNQERVGLDYKTLPSEVEPGAVLLLDDGRIVLNVEAVNGGEVHCTVAAGGVLSNNKGINR
KGGGLSAPALTLKDQEDIRTAVALEADYIAVSFPRSGADIELARHLVREAGGHAAIVAKIERAEAIDALEEIIDAADVIM
VARGDLGVEVGDAAVPGLQKRMIRTARMRNKLVITATQMLESMISSPIPTRAEVSDVANAVLDGTDAVMLSGETAVGHYP
VESIQAMHRVCLEAEKEYDSHHLQAPINDEFEFIDEAIAMASVYAAEHLNVKAIAALTKSGSSVTWLSRSNTNVPIYALT
TERDTRRKLTLYRGVYPYHVEFASQELSKILYDAEETLLRLGAVQRGDLMMLTFGEPIGKAGGTNTLQIVRVGEHRRERH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 4e-83 48
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-57 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-57 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-57 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mfla_2244 YP_546352.1 pyruvate kinase VFG0479 Protein 7e-58 41