Gene Information

Name : thyA (Mfla_0906)
Accession : YP_545015.1
Strain : Methylobacillus flagellatus KT
Genome accession: NC_007947
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 953119 - 953913 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGGTCTATCACGACTTGATGCGCCACGTACTGGAGCAGGGCCACAAGAAGGAAGACCGCACCGGCACCGGTACGCT
GTCCGTATTCGGCTACCAGATGCGCTTCGACCTGTCCGAGGGCTTTCCGCTGCTGACCACCAAGAAGGTTCACCTGAAGT
CCATTATTCATGAGCTGCTCTGGTTTTTGCAGGGCAGTACCAACATTGCCTACCTCAAGGAAAACGGCGTGACCATCTGG
GACGAGTGGGCGGATGCCGAGGGCAACCTGGGGCCAGTGTACGGCTACCAGTGGCGCAATTGGCCCAAACCGGATGGAGG
CCATATCGATCAGATCAGCGAAGTGATAGCGGCCATCAAGCGTAATCCGGACTCTCGCCGTCTGATTGTGTCCGCATGGA
ATGTCGCCGATGTTGACAAGATGAAATTGCCGCCTTGCCATGCGTTTTTCCAGTTCTATGTGGCGGATGGCAAGCTTTCG
TGCCAGTTGTACCAGCGTAGTGCGGATATCTTTCTCGGCGTACCGTTCAATATCGCCTCCTATGCCTTGCTCACCATGAT
GGTGGCGCAGGTATGTGATCTCAAGCTTGGCGATTTTGTACATACACTGGGTGATGCGCATATCTATCTCAATCATCTCG
AGCAGGTGAAGGAGCAATTGTCGCGTGAGCCTTATCCTCTGCCTGTGATGCGGATCAATCCCGAGGTCAAGGATATCTTT
GCTTTCCGTTTCGAGGATTTCACACTGGAGAATTACCAGTCGCATCCCGCTATCAAGGCCCCCGTTGCAGTGTAG

Protein sequence :
MKVYHDLMRHVLEQGHKKEDRTGTGTLSVFGYQMRFDLSEGFPLLTTKKVHLKSIIHELLWFLQGSTNIAYLKENGVTIW
DEWADAEGNLGPVYGYQWRNWPKPDGGHIDQISEVIAAIKRNPDSRRLIVSAWNVADVDKMKLPPCHAFFQFYVADGKLS
CQLYQRSADIFLGVPFNIASYALLTMMVAQVCDLKLGDFVHTLGDAHIYLNHLEQVKEQLSREPYPLPVMRINPEVKDIF
AFRFEDFTLENYQSHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 7e-80 63