Gene Information

Name : metB (UTI89_C4524)
Accession : YP_543467.1
Strain : Escherichia coli UTI89
Genome accession: NC_007946
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4405432 - 4406706 bp
Length : 1275 bp
Strand : +
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
TTGCTCAATCTATACGCAAAGAAGTTTAGATGTCCAGATGTATTGACGTCCATTAACACAATGTTTACTCTGGTGCCTGA
CATTTCACCGACCAAGCCCAGGGAACTTCATCACATGACGCGTAAACAGGCCACCATCGCAGTGCGTAGCGGGTTAAATG
ACGACGAACAGTATGGTTGCGTTGTCCCTCCCATCCATCTTTCCAGTACCTATAACTTTACCGGATTTAATGAACCGCGT
GCGCATGATTACTCGCGGCGCGGCAACCCAACGCGCGATGTGGTTCAGCGTGCGCTGGCAGAACTGGAAGGCGGTGCTGG
TGCCGTACTTACTAATACCGGCATGTCCGCGATTCACCTGGTAACGACCGTCTTTTTGAAACCTGGCGATCTGCTGGTTG
CGCCGCACGACTGCTACGGCGGTAGCTATCGCCTGTTCGACAGCCTGGCGAAACGCGGTTGCTATCGCGTGTTGTTTGTT
GATCAAGGCGATGAACAGGCATTACGGGCAGCGCTGGCAGAAAACCCCAAACTGGTACTGGTAGAAAGCCCAAGTAATCC
ATTGTTACGCGTCGTGGATATTGCGAAAATCTGCCATCTGGCAAGGGAAGTCGGGGCGGTGAGCGTGGTGGATAACACCT
TCTTAAGCCCGGCATTACAAAATCCACTGGCATTAGGTGCCGATCTGGTGTTGCATTCATGCACGAAATATCTGAACGGT
CACTCTGACGTGGTGGCAGGCGTAGTGATTGCTAAAGACCCGGACGTTGTCACTGAACTTGCCTGGTGGGCAAACAATAT
TGGCGTGACGGGCGGCGCGTTTGACAGCTATCTGCTGCTGCGCGGGTTGCGAACGCTGGTGCCGCGAATGGAGCTGGCCC
AGCGCAACGCGCAGGCGATTGTGAAATATCTGCAAACCCAGCCGTTGGTGAAAAAACTGTATCACCCGTCGCTGCCGGAA
AATCAGGGGCATGAAATTGCCGCGCGCCAGCAAAAAGGCTTTGGCGCAATGTTGAGTTTTGAACTGGATGGCGATGAGCA
CACGCTGCGTCGTTTCCTGGGCGAGCTGTCGTTGTTTACGCTGGCGGAATCATTAGGGGGAGTGGAAAGTTTAATCTCTC
ACGCCGCAACCATGACACATGCAGGCATGGCGCCAGAAGCGCGTGCTGCCGCCGGGATCTCCGAGACGCTGCTGCGTATC
TCCACCGGTATTGAAGATGGCGAAGATTTAATTGCCGACCTGGAAAATGGCTTCCGGGCTGCAAACAAGGGGTAA

Protein sequence :
MLNLYAKKFRCPDVLTSINTMFTLVPDISPTKPRELHHMTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPR
AHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFV
DQGDEQALRAALAENPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNG
HSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPE
NQGHEIAARQQKGFGAMLSFELDGDEHTLRRFLGELSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRI
STGIEDGEDLIADLENGFRAANKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-57 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-59 43