Gene Information

Name : UTI89_C3652 (UTI89_C3652)
Accession : YP_542627.1
Strain : Escherichia coli UTI89
Genome accession: NC_007946
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 3580823 - 3581731 bp
Length : 909 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence :
GTGGTACAACACAGCGATGAAAAAGGCGGTGCTATGACCACACTGGCGATTGATATCGGCGGTACTAAACTTGCCGCCGC
GCTGATTGGCGCTGACGGGCAGATCCGCGATCGCCGAGAACTTCCTACGCCTGCCAGCCAGACTCCGCAGGCGCTGCGTG
ATGCCTTATCCGCATTAGTCTCTCCGTTGCAAGCACATGCGCAGCGGGTTGCCATCGCTTCAACCGGAATTATTCGCGAC
GGCAGCTTGTTGGCGCTGAATCCGCATAATCTCGGTGGATTGTTACACTTTCCGTTAGTCAAAACGCTGGAGCAACTTAC
CAATTTGCCGACCATTGCCATTAATGATGCGCAGGCCGCAGCATGGGCGGAGTATCAGGCGCTGGATGGCGATATAACCG
ATATGGTTTTTATCACTGTTTCCACCGGCGTTGGCGGCGGTGTAGTGAGCGGCGGTAAACTGCGTACCGGCCCTGGCGGT
CTGGCGGGGCATATCGGGCATACGCTTGCCGATCCGCATGGTCCAGCCTGCGGCTGTGGACGCACAGGTTGCGTGGAAGC
GATTGCTTCTGGTCGCGGCATTGCAACGGCAGCGCAGGGGGAGTTGGCTGGTGCGAATGCGAAAACTATTTTCACGCGCG
CCGGGCAGGGTGATGAGCAGGCGCAGCAACTGATTCACCGCTCCGCACGTACGCTTGCAAGGCTGATCGCTGATATTAAA
GCCACAACTGATTGCCAGTGCGTGGTGGTCGGTGGCAGCGTTGGTCTGGCAGAAGGGTATCTGGCGCTGGTGGAAACGTA
TCTGGCGCAGGAGCCAGCGGCATTTCATGTTGATTTACTGGCGGCGCACTACCGCCACGATGCAGGTTTACTTGGGGCTG
CGCTGTTGGCCCAGGGAGAAATATTATGA

Protein sequence :
MVQHSDEKGGAMTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPQALRDALSALVSPLQAHAQRVAIASTGIIRD
GSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEYQALDGDITDMVFITVSTGVGGGVVSGGKLRTGPGG
LAGHIGHTLADPHGPACGCGRTGCVEAIASGRGIATAAQGELAGANAKTIFTRAGQGDEQAQQLIHRSARTLARLIADIK
ATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 8e-45 54
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 5e-32 41
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 5e-32 41
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 4e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UTI89_C3652 YP_542627.1 N-acetylmannosamine kinase VFG1115 Protein 2e-32 41