Gene Information

Name : pykF (UTI89_C1868)
Accession : YP_540875.1
Strain : Escherichia coli UTI89
Genome accession: NC_007946
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1791242 - 1792870 bp
Length : 1629 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGGTTTCAGCACTTTGGACTGTAGAACTCAACGACTCAAAAACAGGCACTCACGTTGGGCTGAGACACAAGCACACATT
CCTCTGCACGCTTTTTCGATGTCACCTATCCTTAGAGCGAGGCACAACCACTTTCGTAATACCGGATTCGCTTTCCGGCA
GTGCGCCCAGAAAGCAAGTTTCTCCCATCCTTCTCAACTTAAAGACTAAGACTGTCATGAAAAAGACCAAAATTGTTTGC
ACCATCGGACCGAAAACCGAATCTGAAGAGATGTTAGCTAAAATGCTGGACGCTGGCATGAACGTTATGCGTCTGAACTT
CTCTCATGGTGACTATGCAGAACACGGTCAGCGCATTCAGAATCTGCGCAACGTGATGAGCAAAACTGGTAAAACCGCCG
CTATCCTGCTTGATACCAAAGGTCCAGAAATCCGCACCATGAAACTGGAAGGCGGTAACGACGTTTCTCTGAAAGCGGGT
CAGACCTTTACTTTCACTACTGATAAATCTGTTATCGGCAACAGCGAAATGGTTGCGGTAACGTATGAAGGTTTCACTAC
TGACCTGTCTGTTGGCAACACCGTACTGGTTGACGACGGTCTGATCGGTATGGAAGTTACCGCCATTGAAGGTAACAAAG
TTATCTGTAAAGTGCTGAACAACGGCGACCTGGGCGAAAACAAAGGTGTGAACCTGCCTGGCGTTTCCATTGCCCTGCCA
GCACTGGCTGAAAAAGACAAACAGGACCTGATCTTTGGTTGCGAACAAGGCGTAGACTTTGTTGCTGCTTCCTTTATTCG
TAAGCGTTCTGACGTTATCGAAATCCGTGAGCACCTGAAAGCGCACGGCGGCGAAAACATCCACATCATCTCCAAAATCG
AAAACCAGGAAGGCCTCAACAACTTCGACGAAATCCTCGAAGCCTCTGACGGCATCATGGTTGCGCGTGGCGACCTGGGT
GTAGAAATCCCGGTAGAAGAAGTTATCTTCGCCCAGAAGATGATGATCGAAAAATGTATCCGTGCACGTAAAGTCGTTAT
CACTGCGACCCAGATGCTGGATTCCATGATCAAAAACCCACGCCCGACTCGCGCAGAAGCCGGTGACGTTGCAAACGCCA
TCCTCGACGGTACTGACGCAGTGATGCTGTCTGGTGAATCCGCAAAAGGTAAATACCCGCTGGAAGCGGTTTCTATCATG
GCGACCATCTGCGAACGTACCGACCGCGTGATGAACAGCCGTCTCGAGTTCAACAATGACAACCGTAAACTGCGTATTAC
CGAAGCGGTATGCCGTGGTGCCGTTGAAACTGCTGAAAAACTGGATGCTCCACTGATCGTGGTTGCTACTCAGGGCGGTA
AATCTGCTCGCGCAGTACGTAAATACTTCCCGGATGCCACCATCCTGGCACTGACCACCAACGAAAAAACGGCTCACCAG
TTAGTACTGAGCAAAGGCGTTGTGCCGCAGCTGGTTAAAGAGATCACTTCTACTGATGACTTCTACCGTCTGGGTAAAGA
ACTGGCTCTGCAGAGCGGTCTGGCACACAAAGGTGATGTCGTAGTTATGGTTTCTGGTGCACTGGTACCGAGCGGCACTA
CTAACACCGCATCTGTTCACGTCCTGTAA

Protein sequence :
MVSALWTVELNDSKTGTHVGLRHKHTFLCTLFRCHLSLERGTTTFVIPDSLSGSAPRKQVSPILLNLKTKTVMKKTKIVC
TIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAG
QTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALP
ALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLG
VEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIM
ATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQ
LVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 0.0 96
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 0.0 96
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 0.0 96
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 0.0 96

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_540875.1 pyruvate kinase VFG0479 Protein 0.0 96