Gene Information

Name : leuS (RBE_0311)
Accession : YP_537481.1
Strain : Rickettsia bellii RML369-C
Genome accession: NC_007940
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 348754 - 351249 bp
Length : 2496 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAATATCGAACAGAAATGGCAACAAATTTGGCAAGAAGAAAAAGCCTTTGAAGTACCAAATGAAAGCAGCAAACCTAA
ATATTATGTTTTAGAGATGCTACCTTACCCATCCGGTAAGATTCACGTAGGTCACGTACGTAATTACTCTATAGGCGATG
TAGTTGCTAGATTTATGACCATGCAAGGCTTTAACGTACTTCATCCTATGGGCTGGGACTCTTTCGGCTTGCCGGCAGAA
AATGCAGCAATAAAAAACAACTCTCACCCAAAAGAGTGGACTTATTCGAATATCGAGAATATGAAAAAGCAGCTGAAATC
GATGGGCTTTTCTTATGATTGGTCTAGAGAAATAAATAGTTGCGACCCTGATTATTATAAACATGAGCAAAAATTCTTCT
TAGAGCTTTATGAAAGAAATCTTGCTTATCAAAAAGAATCTCTTGTTAACTGGGATCCGGTTGATAATACTGTACTTGCA
AACGAACAGGTTGTTGATGGGCGTGGTTGGCGTTCAGGTGCGATAGTTGAAAAGCGTTATTTAAAGCAATGGTTCTTAAA
AATCACGAATTATGCTGAAGAGTTATTGAATGAGATTCCAAATTTAACGGAGTGGCCTGAAGCAGTCCGCTCTATGCAAG
AAAAATGGATCGGTAAATCTGTAGGTGCTAACTTTCGTTTCAAAATTAAAGATAATGAAGATGTTATAGAGGTTTTCTCA
ACAAAGCCTGAAACTATTTTTGGAGCTAGCTTTGTTGGTATTGCTTTTAACCATCCAATAATAGAAAAATTAGTTTCTAA
AACTCCTGAAATAGAAAATTTTATCGCTAAATGCTCTAATATAACCGGCTCTGCTGAATTTGACAAAGCTGAGAAAGAGG
GAATATTTACCGGTCTTTACGTTGTTCATCCTTTTGACTCAAATATAACTTTACCTGTTGTTATTACTAATTTCGTGTTG
ATGGATTACGGCACAGGTGCAGTTTTTGGCTGTCCTGCTCATGATCAACGTGACCATGAGTTAGCTGTTAAAATAAATTT
ACCTATAAAGCAGGTAATTGAAGCAGATACTGATGTGCAGAAAGCTGCTTATACTGAAGATGGAATAATTATTAATTCTG
GTTTTCTAAATGGCTTATCTACTAATGAAGCTAAGCAAAGAGTCATAGAAGAATTTGAGAAATTAGGCATAGGCAAACGC
ACAATAAATTATCGCCTGAAAGATTGGGGGATCTCAAGACAACGTTTTTGGGGCTGTCCTATCCCTATAATTCATTGTGA
TTCTTGCGGTTTAGTACCTGTACCTGACTCGGATTTACCGGTTACGCTACCTGATGACGTGAAATTTGATGGTCATGGCA
ATCCTTTAGACAATCACCCAACTTGGAAGCATGTTAACTGTCCAAAATGTAGCAAGCCTGCTATTCGTGAGACCGATACT
TTTGATACATTCTTTGAATCTTCTTGGTATTTCACAAGATATTGTAATAGCCAAGCTCTAGAAATGACTGATAAAAAAGC
TTGCGATTATTGGTTGCCAGTTGATAAATATATTGGCGGCATTGAACATGCGGTAATGCATTTATTATATGCAAGATTTT
TTACTAAGGTAATGAATGAGCAGGATTATGTTAGCGTCCGTGAACCTTTTAAAGGATTATTCACGCAAGGTATGGTGCTG
CACGCTACTTATAAAGACGAGCATAATAATTGGCTATATCCTGAAGAAGTAATTAAAAAAGGTAATGAATTTTTCCATAA
AGAAAATGGCGGTTTGGTTACACAAGGTCGCATCGAGAAAATGAGTAAATCCAAAAAGAACCTCATTGATCTTGAAACTA
TGCAACAGCAATATGGTGCAGATGCAATAAGATTTTTCGTATTATCTGACAGCCCACCGGAAAAAGATTTAGAATGGTCA
GCAAGCGGTATTGAGGGGAGTGCACGTTTTATCAATAAACTTGAACAGATGCAAGAAACGATAATAAAGCTTTCAGATAA
TAAAAATACTAATAAAGAATTAAAGAGGTTAATCCATTTCACTATCAAGCATGTTGCTGAGGATATAAAACATTTTGCTT
TAAATAGAGCAATAGCACGTATGCGTGAACTTTTTAATGCTATATCGAGCGAGATAAATAAAGAAGAAATTGACGTGCAG
AACGCAAAACACGGCTTTAATGTATTAATTCAGCTATTAAATCCATTCATCCCGCATATTACAGAAGAAATTTGGCAAAA
GCTTGGTCATAAAACATTTTTATATAATGCGGCATTTCCTACTTTTGATGAATCGATGCTAGAGCTAGACACATATGTTA
TAGCAGTTCAGGTTAACGGCAAACTTCGTGATACTTATGAGTTTAATACATCCGCAAGTGAAGATGAAATAAAGCAAATT
GCTATTAACTTACCGAAAGTTCAAAAATTTTTAGAAGGCAAAGAGCCTAAAAAAATTATTCTTGTTCCTAAAAAGATCAT
AAATATTATTTGTTGA

Protein sequence :
MNIEQKWQQIWQEEKAFEVPNESSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVVARFMTMQGFNVLHPMGWDSFGLPAE
NAAIKNNSHPKEWTYSNIENMKKQLKSMGFSYDWSREINSCDPDYYKHEQKFFLELYERNLAYQKESLVNWDPVDNTVLA
NEQVVDGRGWRSGAIVEKRYLKQWFLKITNYAEELLNEIPNLTEWPEAVRSMQEKWIGKSVGANFRFKIKDNEDVIEVFS
TKPETIFGASFVGIAFNHPIIEKLVSKTPEIENFIAKCSNITGSAEFDKAEKEGIFTGLYVVHPFDSNITLPVVITNFVL
MDYGTGAVFGCPAHDQRDHELAVKINLPIKQVIEADTDVQKAAYTEDGIIINSGFLNGLSTNEAKQRVIEEFEKLGIGKR
TINYRLKDWGISRQRFWGCPIPIIHCDSCGLVPVPDSDLPVTLPDDVKFDGHGNPLDNHPTWKHVNCPKCSKPAIRETDT
FDTFFESSWYFTRYCNSQALEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQDYVSVREPFKGLFTQGMVL
HATYKDEHNNWLYPEEVIKKGNEFFHKENGGLVTQGRIEKMSKSKKNLIDLETMQQQYGADAIRFFVLSDSPPEKDLEWS
ASGIEGSARFINKLEQMQETIIKLSDNKNTNKELKRLIHFTIKHVAEDIKHFALNRAIARMRELFNAISSEINKEEIDVQ
NAKHGFNVLIQLLNPFIPHITEEIWQKLGHKTFLYNAAFPTFDESMLELDTYVIAVQVNGKLRDTYEFNTSASEDEIKQI
AINLPKVQKFLEGKEPKKIILVPKKIINIIC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-146 41